2023 Cancer Genetics and Epigenetics GRC & GRS

2023 癌症遗传学和表观遗传学 GRC

基本信息

批准号：
10683603
负责人：
Ting Wang
金额：
$ 1.6万
依托单位：
GORDON RESEARCH CONFERENCES
依托单位国家：
美国
项目类别：
财政年份：
2023
资助国家：
美国
起止时间：
2023-05-17 至 2023-11-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10683603
关键词：
3-Dimensional Address Biological Assay CRISPR screen Cancer Control Cells Chromatin Chromatin Structure Clustered Regularly Interspaced Short Palindromic Repeats Collaborations Complement Computer Analysis Computing Methodologies DNA Transposable Elements Data Development Emerging Technologies Engineering Epigenetic Process Future Generations Gene Expression Gene Expression Profile Gene Expression Regulation Genetic Genetic Heterogeneity Genome Genomics Goals Immune response Immunotherapy Individual Inter-tumoral heterogeneity Knowledge Lead Learning Malignant Neoplasms Modernization Molecular Mutation Pathway interactions Play Precision therapeutics Predisposition RNA Research Research Personnel Role Sampling Scientist Surveys Systems Analysis Tail Technology Tumor Biology Untranslated RNA Work cancer diagnosis cancer genetics cancer genome cancer genomics cancer heterogeneity cancer therapy design driver mutation drug discovery epigenetic therapy epigenome epitranscriptome experimental study genome-wide genomic data inhibitor insight meetings novel novel therapeutic intervention posters precision oncology single cell technology symposium targeted treatment tool tumor

项目摘要

SUMMARY The 2023 Conference on Cancer Genetics and Epigenetics will highlight the new development, challenges and opportunities in precision cancer medicine. The conference will focus on emerging technologies and analytical computational methods deciphering mechanistic insights from the studies of individual cancer genome and epigenome leading to drug discoveries and novel precision therapeutics. Heterogeneity of cancer and evolutionary trajectory of cancer will be explored in the context of genetics, epigenetics as well as genome topology, enabled by modern technologies including single cell genomics and CRISPR-based genome and epigenome engineering tools amenable to studies in tumor samples. An emphasis will be put on the emerging roles of non-coding genome and epi-transcriptome in cancer, and how they inform novel therapeutic strategies. Challenges in designing future generation cancer genomics studies and integrating large cancer genomics data will be addressed. This meeting should appeal to a wide range of cancer researchers, molecular biologists, and bioinformaticians seeking to apply the latest genetics and epigenetics discoveries to their work to cancer. In addition to an outstanding set of invited speakers there will be several interactive poster sessions, one minute "poster preview" talks and several talks selected for platform presentation from the submitted abstracts.

概括 2023年癌症遗传学和表观遗传学会议将重点关注癌症遗传学和表观遗传学的新发展、挑战和精准癌症医学的机会。会议将重点关注新兴技术和分析计算方法从个体癌症基因组的研究中破译机制见解表观基因组导致药物发现和新型精准疗法。癌症的异质性和将在遗传学、表观遗传学和基因组的背景下探索癌症的进化轨迹拓扑结构，由单细胞基因组学和基于 CRISPR 的基因组等现代技术实现适用于肿瘤样本研究的表观基因组工程工具。重点将放在新兴非编码基因组和表观转录组在癌症中的作用，以及它们如何为新的治疗策略提供信息。设计下一代癌症基因组学研究和整合大型癌症基因组学数据的挑战将得到解决。这次会议应该会吸引广泛的癌症研究人员、分子生物学家和生物信息学家寻求将最新的遗传学和表观遗传学发现应用于癌症研究。在除了一组杰出的受邀演讲者之外，还将有几场互动海报会议，一分钟 “海报预览”演讲以及从提交的摘要中选择用于平台演示的几场演讲。