Roles of Myotubularin PI 3-phosphatases in Demyelinating Peripheral Neuropathy

肌管蛋白 PI 3-磷酸酶在脱髓鞘性周围神经病中的作用

• 批准号: 8119057
• 负责人: FRED L ROBINSON
• 金额: $ 23.99万
• 依托单位: OREGON HEALTH & SCIENCE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-09-30 至 2012-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8119057
• 关键词: Affect; Award; Biochemical; Biological; Biology; California; Cell physiology; Cells; Charcot-Marie-Tooth Disease; Collection; Complex; Defect; Development; Disease; Electron Microscopy; Electrophysiology (science); Endocytosis; Etiology; Family; Genes; Goals; Grant; Health Sciences; Histology; Homeostasis; Inherited; Intervention; Laboratories; Lead; Limb structure; Membrane Protein Traffic; Mentors; Metabolism; Methods; Modeling; Motor; Mus; Muscle; Mutate; Mutation; Myelin Sheath; Nerve; Nervous system structure; Neurology; Neurons; Neurosciences Research; Oregon; Pathology; Pathway interactions; Patients; Peripheral Nerves; Peripheral Nervous System Diseases; Phase; Phosphatidylinositols; Phosphoric Monoester Hydrolases; Post-Translational Protein Processing; Process; Proteins; Research Personnel; Role; Schwann Cells; Sensory; Signal Transduction; Testing; Therapeutic; Tooth Diseases; Training; Transmembrane Transport; United States; Universities; Work; career; design; disease-causing mutation; insight; member; mouse model; muscle degeneration; myelination; myotubularin; nervous system disorder; phosphatidylinositol 3,5-diphosphate; phosphatidylinositol 3-phosphate; therapy design; trafficking