MINORITY-BASED COMMUNITY ONCOLOGY PROGRAM

基于少数民族的社区肿瘤学计划

• 批准号: 10680599
• 负责人: Balazs Halmos
• 金额: $ 92.94万
• 依托单位: MONTEFIORE MEDICAL CENTER (BRONX, NY)
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-08-01 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10680599
• 关键词: Academic Medical Centers; Address; Adjuvant; Adjuvant Study; Advanced Malignant Neoplasm; Aftercare; Albert Einstein Cancer Center; American College of Radiology Imaging Network; Anal carcinoma; Area; Biological Markers; Black race; Breast Cancer Detection; Cancer Center; Cancer Control; Cancer Patient; Clinical; Clinical Research; Collection; Committee Members; Communities; Community Clinical Oncology Program; County; Coupled; Diagnosis; Doctor of Philosophy; Eastern Cooperative Oncology Group; Ethnic Origin; Evaluation; Faculty; Foundations; Funding; Goals; Health system; Hematopoietic Neoplasms; Hispanic; Home; Infrastructure; Institution; Language; Leadership; Malignant Neoplasms; Measurement; Medical center; Medicine; Mentored Clinical Scientist Development Program; Mentors; Methodology; Methods; Minority; Minority Groups; Minority Participation; Mission; Morbidity - disease rate; NCI-Designated Cancer Center; Neuropathy; New York; Nivolumab; Outcome; Outcomes Research; Patient Care; Patients; Pilot Projects; Prevention; Protocols documentation; Recording of previous events; Research; Research Personnel; Resources; Role; Science; Site; System; Therapeutic; Therapeutic Trials; Training; Training Programs; Training Support; Training and Education; Translational Research; Underrepresented Minority; United States; Urban Community; anticancer research; base; biomarker validation; black women; cancer care; cancer clinical trial; cancer health disparity; cancer imaging; cancer prevention; cancer therapy; care delivery; career; college; experience; federal poverty level; financial toxicity; health care delivery; health related quality of life; innovation; institutional capacity; malignant breast neoplasm; member; minority engagement; minority patient; minority subjects; mortality; novel; oncology program; patient engagement; population based; postgraduate education; precision medicine; programs; prospective; screening; success; taxane; team-based care; treatment trial; trial design; trial planning; underserved community; underserved minority

The overall goals of the Montefiore-Einstein minority-based NCORP community site are to advance the diagnosis, prevention, and management of early and advanced cancer by participating in NCORP trials as a minority/underserved community site, and contributing scientifically and administratively to the NCORP research bases. This will be accomplished by leveraging the strengths of the Montefiore Health System (MHS), including Montefiore Medical Center (MMC), which brings strengths in integrated patient care and innovative health care delivery systems in an academic medical center serving a largely minority population, and the Albert Einstein College of Medicine and Cancer Center (Einstein), which brings strength in training and education, and in baslc, translational, and clinical research through its NCI- designated cancer center. The MMC-Einstein program also brings critical leadership to the NCORP Research Bases, including ECOG-ACRIN, Alliance, and NRG, including leadership roles at the level of the group chair's office, scientific committee chair (or co-chair), and protocol chair (or co-chair). Our plans build upon our long-standing involvement in all aspects of cancer research as a main member of ECOG for 45 years and an NCI-designated cancer center for 48 years, and a strong history of minority accrual to cancer treatment trials (about 65%of all patients). MMC serves the Bronx, an urban community of 1.47 million residents, of whom 89% are minorities and 29% live below the federal poverty level. In the prior funding period we had a strong track record scientific contributions to the NCORP research bases, and met our accrual targets with exceptionally strong minority participation. In the next funding period, we will continue our strong leadership in cancer therapeutics (EA2165), expand the spectrum of our activities to include new programs in cancer imaging and screening (TMIST), cancer control/prevention (EAZ171), and cancer care delivery research (CCDR). The MMC-Einstein NCORP program is led by faculty with experience in cancer therapeutics and biomarker research (J. Sparano, MD), precision medicine and immunoncology (B. Halmos, MD), and CCDR and cancer prevention/control (B. Rapkin, PhD), and is supported by a cadre of other investigators with a broad range of expertise, some of whom benefited from NCI- funded K12 training program in clinical cancer research.

以 Montefiore-Einstein 少数族裔为基础的 NCORP 社区网站的总体目标是推动 通过参与 NCORP 来诊断、预防和管理早期和晚期癌症 作为少数群体/服务不足的社区站点进行试验，并在科学和行政上为 NCORP 研究基地。这将通过利用 Montefiore Health 的优势来实现 系统 (MHS)，包括 Montefiore 医疗中心 (MMC)，它带来了综合患者的优势 学术医疗中心的护理和创新医疗保健提供系统，主要服务于 少数族裔人口，以及阿尔伯特·爱因斯坦医学和癌症中心（爱因斯坦）学院， 通过其 NCI- 在培训和教育以及 baslc、转化和临床研究方面带来实力 指定癌症中心。 MMC-爱因斯坦项目还为 NCORP 带来了关键的领导力 研究基地，包括 ECOG-ACRIN、Alliance 和 NRG，包括在 小组主席办公室、科学委员会主席（或联合主席）和礼宾主席（或联合主席）。我们的计划 以我们作为主要成员长期参与癌症研究的各个方面为基础 ECOG 已有 45 年历史，NCI 指定癌症中心已有 48 年历史，并且拥有悠久的少数民族历史 癌症治疗试验的累积（约占所有患者的 65%）。 MMC 为布朗克斯 (Bronx) 提供服务，这是一个城市社区 147 万居民，其中 89% 是少数族裔，29% 生活在联邦贫困线以下。在 在之前的资助期间，我们对 NCORP 研究基地做出了良好的科学贡献，并且 通过异常强烈的少数族裔参与，实现了我们的权责发生制目标。在下一个资助期内，我们将 继续我们在癌症治疗领域的强大领导地位 (EA2165)，扩大我们的活动范围 包括癌症成像和筛查 (TMIST)、癌症控制/预防 (EAZ171) 和 癌症护理提供研究（CCDR）。 MMC-Einstein NCORP 项目由具有以下资格的教师领导： 在癌症治疗和生物标志物研究（J. Sparano，医学博士）、精准医学和 免疫肿瘤学（B. Halmos，医学博士），以及 CCDR 和癌症预防/控制（B. Rapkin，博士），并且 得到了一批具有广泛专业知识的其他研究人员的支持，其中一些人受益于 NCI- 资助临床癌症研究的 K12 培训计划。

项目成果

Systematic Patient Navigation Strategies to Scale Breast Cancer Disparity Reduction by Improved Cancer Prevention and Care Delivery Processes.

系统性患者导航策略通过改进癌症预防和护理服务流程来缩小乳腺癌差异。

• 发表时间: 2020-12
• 影响因子: 4
• 作者: Simon, Melissa A;Trosman, Julia R;Rapkin, Bruce;Rittner, Sarah S;Adetoro, Elizabeth;Kirschner, Marcie C;O'Brian, Catherine A;Tom, Laura S;Weldon, Christine B
• 通讯作者: Weldon, Christine B

Understanding Racial Disparities in Gastrointestinal Cancer Outcomes: Lack of Surgery Contributes to Lower Survival in African American Patients.

了解胃肠癌结果的种族差异：缺乏手术导致非洲裔美国患者的生存率较低。

• 发表时间: 2021-03
• 作者: Bliton, John N;Parides, Michael;Muscarella, Peter;Papalezova, Katia T;In, Haejin
• 通讯作者: In, Haejin

Reducing Disparities in Cancer Screening and Prevention through Community-Based Participatory Research Partnerships with Local Libraries: A Comprehensive Dynamic Trial.

通过与当地图书馆基于社区的参与性研究伙伴关系减少癌症筛查和预防方面的差异：一项综合动态试验。

• 发表时间: 2017-09
• 影响因子: 3.1
• 作者: Rapkin, Bruce D;Weiss, Elisa;Lounsbury, David;Michel, Tamara;Gordon, Alexis;Erb;Sabino;Carpenter, Alison;Schwartz, Carolyn E;Bulone, Linda;Kemeny, Margaret
• 通讯作者: Kemeny, Margaret

Clinical Utility of 18F-FDG PET/CT in Staging Localized Breast Cancer Before Initiating Preoperative Systemic Therapy.

18F-FDG PET/CT 在开始术前全身治疗前对局限性乳腺癌进行分期的临床应用。

• 发表时间: 2020-09
• 作者: Ko, Heidi;Baghdadi, Yaser;Love, Charito;Sparano, Joseph A
• 通讯作者: Sparano, Joseph A

Expanding Criteria for Prognostic Stage IA in Hormone Receptor-Positive Breast Cancer.

扩大激素受体阳性乳腺癌 IA 期预后标准。

• 发表时间: 2021-11-29
• 作者: Kantor, Olga;King, Tari A;Shak, Steven;Russell, Christy A;Giuliano, Armando E;Hortobagyi, Gabriel N;Burstein, Harold J;Winer, Eric P;Dey, Tanujit;Sparano, Joseph A;Mittendorf, Elizabeth A
• 通讯作者: Mittendorf, Elizabeth A