Preventing Drug Abuse among Hispanic Adolescents

防止西班牙裔青少年滥用药物

• 批准号: 8220111
• 负责人: STEVEN Paul SCHINKE
• 金额: $ 70.42万
• 依托单位: COLUMBIA UNIV NEW YORK MORNINGSIDE
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-15 至 2017-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8220111
• 关键词: 13 year old; 18 year old; Acculturation; Address; Adolescence; Adolescent; Alcohols; Americas; Artificial Intelligence; Award; Back; Behavior; Behavioral; CD-ROM; Child; Cigarette; Clinical; Clinical Research; Clinical Sciences; Cognitive; Communities; Competence; Computers; Data; Data Collection; Dominican; Drug abuse; Drug usage; Emotional; Enrollment; Environment; Epidemiology; Face; Family; Feedback; Friends; Future; Goals; Health Services Research; Hispanics; Home environment; Household; Human; Immigration; Institutes; Internet; Intervention; Learning; Marijuana; Measurement; Measures; Mediator of activation protein; Monitor; Outcome; Outcome Study; Participant; Personal Computers; Play; Prevention approach; Prevention program; Puerto Rican; Randomized Clinical Trials; Recruitment Activity; Research; Research Design; Resources; Risk; Risk Factors; Sampling; School-Age Population; Schools; Science; Sex Characteristics; Speed; Stress; Testing; Time; Training; Translational Research; United States; Universities; Work; Youth; adolescent drug use; arm; base; computerized; drug abuse prevention; follow-up; high risk; intervention effect; intervention program; member; novel strategies; post intervention; prevent; programs; response; simulation; skills; social cognitive theory; social networking website; theories; trend

DESCRIPTION (provided by applicant): This resubmitted application addresses the weaknesses identified in its initial review. Prepared in response to PAS-09-001, Drug Abuse Epidemiology and Services Research in Cooperation with the Clinical and Translational Science Awards Consortium (R01), the application lays plans to develop, test, and disseminate an interactive program to delay the onset of drug use and to prevent harmful use and abuse among Hispanic youths. Study participants will come from Northern Manhattan, home to a large population of Hispanic families from Dominican, Puerto Rican, and other backgrounds. Grounded in bicultural competence and social learning theories, the prevention program will equip youths with cognitive and behavioral skills to address ethnic-specific and pan-ethnic risk and protective factors associated with drug use among Hispanic adolescents. Youths will access the program's 10 initial sessions and annual booster sessions via personal computer. Through a human simulation interaction platform, the program will employ artificial intelligence, graphic portrayals of emotional states, and a branched learning environment in which youths can acquire, try out, receive feedback on, and master new interpersonal skills. Cultural content woven into every programmatic session, together with sessions expressly dedicated to issues of acculturation, Hispanic traditions, and bicultural stress will give the program thematic coherence and enhance its attraction and value. The study design is a randomized clinical trial. Enrolled 11-, 12-, and 13-year-old youths will complete baseline measures, intervention-arm youths will receive the initial prevention program, and all youths will complete post-intervention and 12-, 24-, and 36-month follow-up measures. Intervention-arm youths will additionally receive pairs of booster sessions after they complete 12- and 24-month follow-up measurements. Hypothesis testing analyses will examine 30-day drug use rates between arms and across follow-up measurement occasions. In addition, we will analyze intervention effects on mediator variables associated with drug use risk and protective factors. We also will assess the extent to which changes on mediator variables explain drug use differences. And, we will examine gender differences, and, to the extent possible, immigration status and ethnic background differences in study outcomes. At the conclusion of the trial, and assuming that longitudinal findings support the tested prevention approach, we will revise the program to increase its appeal for Hispanic youth across America, and we will disseminate the revised program through a variety of online resources. Throughout, we will monitor program dissemination. PUBLIC HEALTH RELEVANCE: This study will longitudinally test a computerized drug abuse prevention program for Hispanic adolescents. The culturally-tailored prevention program aims to strengthen and sustain protective factors while equipping youths with the necessary information and skills to reduce risk factors associated with cigarettes, alcohol, marijuana, and other harmful drug use.

描述（由申请人提供）：此重新提交的应用程序解决了其初始审查中确定的弱点。该申请与临床和转化科学奖联盟（R01）合作，根据PAS-09-001的响应，滥用药物滥用流行病学和服务研究，该申请计划制定计划，以开发，测试和传播互动计划，以延迟毒品使用的发作，并在西班牙裔青年中预防和防止有害的使用和虐待。研究参与者将来自曼哈顿北部，那里是来自多米尼加，波多黎各人和其他背景的大量西班牙裔家庭的所在地。预防计划以双文化能力和社会学习理论为基础，将使年轻人具有认知和行为能力，以应对西班牙裔青少年中与药物使用相关的民族特异性和泛种族风险和保护因素。年轻人将通过个人计算机访问该计划的10个初次会议和年度助推器会议。通过人类的模拟互动平台，该计划将采用人工智能，情感状态的图形刻画以及年轻人可以在其中获取，尝试，接收反馈并掌握新的新际交往能力的分支学习环境。文化内容融入了每个程序性会议，并明确致力于适应，西班牙裔传统和双文化压力的会议，这将赋予该计划的主题连贯性并增强其吸引力和价值。研究设计是一项随机临床试验。注册的11岁，12岁和13岁的年轻人将完成基线措施，干预武器青​​年将获得初步的预防计划，所有年轻人将完成干预后以及12-、24-和36个月的随访措施。干预武器青​​年在完成12个月和24个月的随访测量后，还将获得助推器的成对。假设测试分析将检查手臂之间以及随访测量场合之间的30天药物使用率。此外，我们将分析对与药物使用风险和保护因素相关的调解人变量的干预影响。我们还将评估介体变量的变化解释药物使用差异的程度。而且，我们将研究性别差异，并在可能的范围内，在研究结果中的移民身份和种族背景差异。在审判结束时，假设纵向发现支持测试的预防方法，我们将修改该计划，以增加对整个美国西班牙裔青年的吸引力，我们将通过各种在线资源来传播修订后的计划。在整个过程中，我们将监视程序传播。 公共卫生相关性：这项研究将纵向测试西班牙裔青少年的计算机预防药物滥用计划。经过文化的预防计划旨在加强和维持保护因素，同时为年轻人提供必要的信息和技能，以减少与香烟，酒精，大麻和其他有害药物使用相关的危险因素。