Research Experiences in Childhood Heart, Lung, and Blood Science - REaCH LABS

儿童心脏、肺和血液科学的研究经验 - REaCH LABS

• 批准号: 10681038
• 负责人: Deena Chisolm
• 金额: $ 16.51万
• 依托单位: RESEARCH INST NATIONWIDE CHILDREN'S HOSP
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10681038
• 关键词: Admission activity; Adult; African American; Age; Area; Biomedical Research; Blood; Budgets; Cause of Death; Child; Child health equity; Childhood; Chronic; Clinical; Congenital Abnormality; Development; Discipline of Nursing; Ecosystem; Educational Curriculum; Educational workshop; Eligibility Determination; Ethnic Origin; Exposure to; Faculty; Funding; Growth; Health; Health Sciences; Heart; Heart Diseases; Hematological Disease; Infant; Internships; Interview; Leadership; Lung; Lung diseases; Measures; Medical; Medical Students; Medicine; Mentors; Mentorship; Minority; Morbidity - disease rate; National Heart, Lung, and Blood Institute; Ohio; Organizational Affiliation; Outcome; Participant; Patient Recruitments; Pediatric Hospitals; Pediatric Research; Population; Population Scientist Supplement (R25); Postbaccalaureate; Postdoctoral Fellow; Process; Publications; Qualifying; Race; Readiness; Research; Research Personnel; Research Priority; Research Project Grants; Respiratory Disease; Respiratory Tract Infections; STEM career; Science; Structure; Students; Training; Underrepresented Students; United States National Institutes of Health; Universities; Youth; career; cohort; demographics; design; experience; follow-up; graduate school; graduate student; health disparity; health equity promotion; high school; interest; medical schools; meetings; member; mortality; neonate; next generation; novel; peer; peer coaching; programs; recruit; role model; skills; socioeconomics; student participation; success; summer research; undergraduate student

Abstract Disease of the heart, lungs and blood are associated with substantial morbidity and mortality in pediatric populations. Children make up 22% of the U.S. population, yet the NIH’s $4 billion pediatric research portfolio makes up only 10% of the annual NIH research budget. The Nationwide Children’s Hospital Research Experiences in Childhood Heart, Lung and Blood Sciences (REaCH-LABS) is designed to provide meaningful summer opportunities for undergraduate students from backgrounds underrepresented in medicine (URiM) in scientific areas of interest to NHLBI. Each annual cohort will include 5 new participants who are eligible for up to two years in the program (yielding a total of 10 participating students each year). Our exceptional research mentorship faculty, representing diversity in both science and demographics, is comprised of over 20 PIs with current or past NHLBI funding or other relevant federal funding. Participants will be situated within a dynamic ecosystem of pipeline programs at Nationwide Children’s Hospital spanning high school research internships thoughT32-funded post-doctoral programs. The curriculum will include 1) an immersive summer research experience in a research team conducting NHLBI priority research; 2) assignment of a near-peer (medical or graduate student) mentor to support readiness for transition to graduate or medical school; 3) weekly Heart of the Matter research seminars providing exposure to active research projects and clinical careers; and 4) weekly professional development workshops focused on medical school applications, MCATs, interviewing and other relevant topics. Research team experiences will include meaningful mentored projects that build skills and produce a product suitable for presentation at the close of the internship. Highly qualified internal and external review boards will provide guidance on implementation and outcomes and a structured approach to follow-up will tracking of long-term program outcomes. To maximize our pool of well-qualified URiM candidates, this project includes a novel partnership with the Student National Medical Association (SNMA), the nation’s largest organization supporting African American medical students, and its undergraduate affiliate organization, the Minority Association of Pre-Health Students (MAPS). SNMA leadership and members will engage in project oversight, participant recruitment, near-peer mentoring, and panel presentations, serving as both contributors and role models. REaCH-LABS is committed to recruiting, engaging, and supporting URiM participants in a structure that supports their oft-times unique needs in a way that smooths their path to a biomedical research career. Our program design will generate well-qualified graduates who add to the diversity of researchers and research questions, promoting health equity for children and the adults that they will become.

抽象的 心脏、肺和血液疾病与儿科的高发病率和死亡率相关 儿童占美国人口的 22%，但 NIH 的儿科研究组合已达 40 亿美元。 仅占 NIH 年度研究预算的 10%。 儿童心、肺和血液科学经验 (REACH-LABS) 旨在提供有意义的 为医学界（URiM）背景不足的本科生提供暑期机会 NHLBI 感兴趣的科学领域每个年度队列将包括 5 名符合资格的新参与者。 该项目为期两年（每年共有 10 名学生参与）。 导师制代表了科学和人口统计学方面的多样性，由 20 多名 PI 组成， 当前或过去的 NHLBI 资金或其他相关联邦资金将处于动态范围内。 全国儿童医院涵盖高中研究实习的管道项目生态系统 thoughT32 资助的博士后项目将包括 1) 沉浸式暑期研究。 在研究团队中进行 NHLBI 优先研究的经验；2) 分配近同行（医学或 研究生）导师，支持为研究生或医学院的过渡做好准备 3）每周的核心； Matter 研究研讨会提供活跃的研究项目和临床职业的机会；4) 每周一次的专业发展研讨会，重点关注医学院申请、MCAT、面试和 其他相关主题的研究团队经验将包括培养技能的有意义的指导项目。 并制作出适合在实习结束时进行演示的产品。 外部审查委员会将提供有关实施和结果的指导以及结构化方法 后续工作将跟踪长期计划成果，以最大限度地扩大我们合格的 URiM 库。 候选人，该项目包括与学生全国医学协会（SNMA）的新颖合作伙伴关系， 全国最大的支持非裔美国医学生的组织及其本科生附属机构 组织、健康前学生少数民族协会 (MAPS) 领导层和成员将。 参与项目监督、参与者招募、同行指导和小组演示，作为 REaCH-LABS 致力于招募、参与和支持 URiM。 参与者的结构能够支持他们经常的独特需求，从而为他们提供顺利的道路 我们的项目设计将培养高素质的毕业生，增加多样性。 研究人员和研究问题，促进儿童和成人的健康公平 变得。

项目成果

Prevalence of Duffy null and its impact on hydroxyurea in young children with sickle cell disease in the United States.

美国镰状细胞病幼儿中达菲无效的患病率及其对羟基脲的影响。

• 发表时间: 2024-06
• 影响因子: 3.2
• 作者: Oladipupo, Fathia;Stanek, Joseph;Walden, Joseph;Young, Jennifer;Rose, Melissa J;Nicol, Kathleen;Villella, Anthony;Creary, Susan
• 通讯作者: Creary, Susan