Social determinants of cardiovascular disease risk over the life course

生命历程中心血管疾病风险的社会决定因素

• 批准号: 10673050
• 负责人: ANA V DIEZ-ROUX
• 金额: $ 24.62万
• 依托单位: DREXEL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-01 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10673050
• 关键词: Americas; Applications Grants; Cardiovascular Diseases; Central America; Central American; Cities; Collaborations; Communities; Country; Data Analytics; Development; Doctor' s Degree; Educational workshop; Elements; Epidemiologic Methods; Faculty; Healthcare Systems; Incidence; Income; Inequity; Information Dissemination; Interdisciplinary Study; Intervention; Journals; Lead; Life Cycle Stages; Life course epidemiology; Longevity; Mentors; Mentorship; Methods; Neighborhoods; Panama; Periodicals; Persons; Phase; Policies; Policy Maker; Postdoctoral Fellow; Prevalence; Public Health; Publications; Research; Research Methodology; Research Personnel; Risk Factors; Site; Students; Training; Training Activity; Training Programs; Translational Research; Translations; Universities; Urbanization; Visit; cardiovascular disorder risk; data management; doctoral student; interdisciplinary approach; mid-career faculty; nutrition; prevent; programs; social; social determinants; social health determinants; social influence; webinar

PROJECT SUMMARY Over the last several decades, cardiovascular disease (CVD) incidence and the prevalence of CVD risk factors have steadily increased in the Central American region, in contrast to other countries of the Americas where CVD is no longer increasing or on the decline. The rise of CVD in the region has occurred in tandem with increases in urbanization and widening social inequities, and poses a growing, untenable burden for its limited public health and health care systems. While research in high income countries highlights interventions on social determinants of health as levers to prevent cardiovascular disease, less is known about the specific, intervenable social determinants that can help prevent CVD in Central America. Training and mentoring of the local workforce in identifying relevant research questions, in the use of appropriate research methods, and in the dissemination of results to the scientific community, the public, and policy makers is critical to identify and develop interventions to prevent CVD in the region. To this end, researchers from Drexel University and the Institute for Nutrition of Central America and Panama (INCAP) have partnered to establish a training program focused on developing the research capabilities of trainees and local capacity building in the conduct of policy- relevant research on the influence of social determinants and place-based factors on CVD risk across the lifespan. Key elements include: (1) a focus on factors at multiple levels (from cities, to neighborhoods, to persons) and over the lifecourse, (2) the use of rigorous state-of-the-art methods; (3) an emphasis on the value of interdisciplinary approaches; and (4) dissemination and translation of research findings into policy actions. The program leverages the SALURBAL Study, a unique multidisciplinary collaboration focused on the region. Training activities will include (1) training of up to 3 PhD students or up to 5 Masters students; (2) support for up to 4 postdoctoral fellows and 11 visiting faculty fellows promoting the development of junior and mid-career faculty; (3) annual workshops and periodic webinars and journal clubs on social determinants of health, CVD and lifecourse epidemiology, and research methods; (4) support for the development of data management and analytical capacity on site; and (5) enhanced south-south collaborations in mentorship and research. As a result of the program we expect to see an increase in the number researchers with Masters or Doctoral degrees at INCAP, an increase in the number of publications and grant proposals submitted by local researchers, larger numbers of mentoring relationships, publications, and grant proposals involving collaborations between INCAP and other countries in the region, greater capacity for data management/analysis at INCAP, and greater engagement of local investigators in CVD research and dissemination activities, including policy translation in the region. We also expect to see a continuation proposal to this training program submitted by INCAP as lead at the end of the this initial phase of the program.

项目概要 过去几十年来，心血管疾病 (CVD) 发病率和 CVD 危险因素的患病率 与美洲其他国家相比，中美洲地区的人口数量稳步增长 CVD 不再增加或减少。该地区 CVD 的兴起与 城市化进程的加快和社会不平等的扩大，给有限的社会带来了越来越大的难以承受的负担 公共卫生和医疗保健系统。虽然高收入国家的研究强调了对 健康的社会决定因素作为预防心血管疾病的杠杆，但对其具体的了解较少， 可干预的社会决定因素有助于预防中美洲的心血管疾病。培训和指导 当地劳动力确定相关研究问题、使用适当的研究方法以及 向科学界、公众和政策制定者传播结果对于确定和 制定干预措施以预防该地区的心血管疾病。为此，德雷塞尔大学和 中美洲和巴拿马营养研究所 (INCAP) 合作建立了一个培训计划 重点发展受训人员的研究能力和地方政策执行能力建设 社会决定因素和地方因素对心血管疾病风险影响的相关研究 寿命。关键要素包括：（1）关注多个层面的因素（从城市到社区，到 人）以及整个生命周期，（2）使用严格的最先进的方法； (3)强调价值 跨学科方法； (4) 将研究成果传播并转化为政策行动。 该计划利用了 SALURBAL 研究，这是一项专注于该地区的独特的多学科合作。 培训活动将包括（1）培训最多3名博士生或最多5名硕士生； (2) 支持 多达 4 名博士后研究员和 11 名访问学者，促进初级和中期职业发展 学院; (3) 关于健康、心血管疾病社会决定因素的年度研讨会和定期网络研讨会和期刊俱乐部 生命全程流行病学和研究方法； (4)支持数据管理和开发 现场分析能力； (5) 加强指导和研究方面的南南合作。作为一个 根据该计划的结果，我们预计拥有硕士或博士学位的研究人员数量将会增加 INCAP 学位、当地提交的出版物和拨款提案数量增加 研究人员、大量的指导关系、出版物和资助提案涉及 INCAP 与该地区其他国家之间的合作，更大的数据能力 INCAP 的管理/分析，以及当地研究人员更多地参与 CVD 研究和 传播活动，包括该地区的政策翻译。我们也期待看到后续 INCAP 在该计划初始阶段结束时作为牵头人提交了对此培训计划的提案。