Digital clinical hypnosis for chronic pain management

用于慢性疼痛管理的数字临床催眠

• 批准号: 10696872
• 负责人: Mark P Jensen
• 金额: $ 32.46万
• 依托单位: HYPNOSCIENTIFIC, INC.
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-05-16 至 2025-04-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10696872
• 关键词: Absence of pain sensation; Address; Adult; Adverse event; Affect; Agreement; Anxiety; Benchmarking; Businesses; Clinical; Copyright; Data; Development; Effectiveness; Enrollment; Feasibility Studies; Focus Groups; Goals; Guidelines; Health; Health Personnel; Healthcare Systems; Hypnosis; Individual; Institution; Insurance; Knowledge; Marketing; Measures; National Center for Complementary and Integrative Health; Opioid; Outcome; Pain; Pain intensity; Pain management; Persons; Phase; Policies; Provider; Public Health; Randomized; Research; Research Support; Rights; Sampling; Small Business Technology Transfer Research; System; Techniques; Technology; Testing; Therapeutic; Training; United States; Universities; Update; Washington; chronic pain; chronic pain management; commercialization; cost; dashboard; design; digital; digital treatment; efficacy evaluation; empowerment; feasibility testing; handheld mobile device; hypnotic; improved; innovation; interest; novel; pain self-management; programs; prototype; response; side effect; sleep quality; telehealth

Project Summary Chronic pain is a prevalent, disabling problem affecting as many as 116 million adults in the United States. However, there are very few treatment options for chronic pain management, and those that are available are inadequate for the majority of those with this condition. Many also have significant negative side effects or are associated with significant adverse events. A growing body of research supports the short- and long-term benefits of hypnosis treatment for chronic pain. Hypnosis treatment has also been shown to have few negative side effects, while also having additional benefits over and above reductions in pain intensity, including reductions in anxiety and improvements in sleep quality. However, access to hypnosis treatment is limited because few health care providers are trained in its use. HypnoScientific, Inc. was established to increase access to effective hypnosis treatment by developing and making it available online and via mobile devices, i.e., digital hypnosis. To maximize efficacy, HypnoScientific’s products are informed by the findings from a well- established and ongoing research program studying the mechanisms of hypnotic analgesia, including pilot research that has tested a hypnosis digital therapeutic prototype. The first aim of the currently proposed Phase I project is to develop the hypnosis digital therapeutic prototype further by: (1) updating and increasing the number of hypnosis media tracks offered, (2) designing a ruleset for content delivery, (3) developing UI/UX standards to optimize ease of use and efficacy, and (4) developing a content management system consistent with this ruleset, that would allow content to be provided to individuals with chronic pain via an existing telehealth company’s platform. The project’s second aim is to evaluate the feasibility of the technology delivery system developed in Aim 1 in a sample of 50 individuals with chronic pain. These individuals will be randomized to having more access (i.e., 8 full weeks) or less access (i.e., 4 weeks of no access followed by 4 weeks of access) to the therapeutic, and feasibility variables will be collected during and after the trial. The findings from this trial will allow us to determine if the proposed approach for making hypnosis treatment more accessible to the millions of individuals who could benefit from it is viable. The findings will also provide data that will inform the design of a definitive trial testing the technology in a Phase II project.

项目概要 慢性疼痛是一种普遍存在的致残问题，影响着美国多达 1.16 亿成年人。 然而，慢性疼痛管理的治疗方案很少，可用的治疗方案有 对于大多数患有这种疾病的人来说，许多药物还具有显着的副作用。 越来越多的研究支持短期和长期的不良事件。 催眠治疗对慢性疼痛的好处 催眠治疗也被证明几乎没有负面影响。 副作用，同时除了减轻疼痛强度之外还具有其他好处，包括 减少焦虑并改善睡眠质量然而，获得催眠治疗的机会有限。 因为很少有医疗保健提供者接受过其使用方面的培训，因此 HypnoScientific 公司的成立就是为了增加这种技术的使用。 通过开发并通过在线和移动设备提供有效的催眠治疗， 即数字催眠，为了最大限度地提高功效，HypnoScientific 的产品以来自良好的研究结果为基础。 已建立和正在进行的研究催眠镇痛机制的研究计划，包括试点 测试催眠数字治疗原型的研究是当前提出的阶段的第一个目标。 我的项目是通过以下方式进一步开发催眠数字治疗原型：（1）更新和增加 提供的催眠媒体曲目数量，(2) 设计内容交付规则集，(3) 开发 UI/UX 标准以优化易用性和功效，以及 (4) 开发一致的内容管理系统 有了这个规则集，就可以通过现有的方式向患有慢性疼痛的个人提供内容 该项目的第二个目标是评估技术交付的可行性。 目标 1 中开发的系统以 50 名患有慢性疼痛的个体为样本。 随机分配为具有更多访问权限（即，整整 8 周）或较少访问权限（即，4 周没有访问，然后是 4 周） 将在试验期间和试验后收集治疗的可行性变量。 这项试验的结果将使我们能够确定所提议的方法是否可以使催眠治疗更加有效 研究结果还将提供可行的数据，让数以百万计的人能够从中受益。 这将为第二阶段项目中对该技术进行最终试验的设计提供信息。