LONG-TERM RHIGF-I TREATMENT IN CHILDREN WITH SHORT STATURE DUE TO GHIS

因 GHIS 导致身材矮小的儿童的长期 RHIGF-I 治疗

• 批准号: 7625499
• 负责人: LOUIS E UNDERWOOD
• 金额: $ 1.13万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7625499
• 关键词: Child; Computer Retrieval of Information on Scientific Projects Database; Daily; Funding; Grant; Growth; Human; Injection of therapeutic agent; Institution; Insulin-Like Growth Factor I; Laron Syndrome; Names; Pharmaceutical Preparations; Purpose; Recombinants; Research; Research Personnel; Resources; Safety; Source; Testing; Time; United States National Institutes of Health; improved; research study

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this research study is to evaluate the safety and efficacy of an experimental drug named recombinant human insulin-like growth factor I (rhIGF-I) for the treatment of short stature. The purpose of the study is to see if injections of rhIGF-I two times daily will cause improved growth in children with growth hormone insensitivity syndrome, and to test the long-term safety of rhIGF-I.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究的目的是评估一种名为重组人胰岛素样生长因子 I (rhIGF-I) 的实验药物治疗身材矮小的安全性和有效性。该研究的目的是观察每天两次注射rhIGF-I是否会改善患有生长激素不敏感综合征的儿童的生长，并测试rhIGF-I的长期安全性。