SAGITTAL SYNOSTOSIS: 3D PHOTOGRAPHY PROJECT

矢状连接：3D 摄影项目

• 批准号: 7603537
• 负责人: ANNE V HING
• 金额: $ 0.04万
• 依托单位: UNIVERSITY OF WASHINGTON
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7603537
• 关键词: Complex; Computer Retrieval of Information on Scientific Projects Database; Condition; Data; Development; Diagnosis; Environmental Risk Factor; Family; Family member; Forehead; Funding; Future; Genetic; Grant; Head; Individual; Institution; Measures; Methods; Photography; Pilot Projects; Relative (related person); Reporting; Research; Research Personnel; Research Proposals; Resources; Scaphycephaly; Shapes; Source; Time; United States National Institutes of Health

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This pilot study is being done to determine the best method of characterizing head shape differences observed in individuals with sagittal synostosis and their relatives. Data collected and analyzed in this study will be used as preliminary data in a larger research proposal to identify causes of sagittal synostosis. Sagittal synostosis results in scaphocephaly, a long narrow head shape with a prominent forehead and narrow bulging occiput. In a few families, additional relatives have been diagnosed with sagittal synostosis. Some families have reported family members with long narrow heads or large foreheads, who have not been diagnosed with sagittal synostosis. We propose that sagittal synostosis is a complex condition due to genetic and environmental factors. At this time causes of sagittal synostosis are largely unexplained. Development of a reproducible and accurate three-dimensional measure of head shape will be important for future studies to identify genetic causes of sagittal synostosis.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项试验研究是为了确定表征在矢状突触及其亲属的个体中观察到的头部形状差异的最佳方法。在这项研究中收集和分析的数据将用作较大的研究建议中的初步数据，以识别矢状突触的原因。 矢状突触导致肩caph骨，这是长长的狭窄头形，额头突出和狭窄的枕骨。在一些家庭中，其他亲戚被诊断出患有矢状突触。 一些家庭报告说，尚未被诊断为矢状突触的家庭成员的头部长狭窄或额头很大。 我们建议，由于遗传和环境因素，矢状突触是一种复杂的状况。目前，矢状突触的原因在很大程度上无法解释。可再现和准确的三维头形测量的发展对于未来的研究，以确定矢状突触的遗传原因很重要。