Preventing High-Risk Sexual Behaviors in Young Heterosexual Latino Couples

预防年轻异性恋拉丁裔夫妇的高风险性行为

• 批准号: 7685707
• 负责人: DAVID PEREZ-JIMENEZ
• 金额: $ 29.55万
• 依托单位: UNIVERSITY OF PUERTO RICO RIO PIEDRAS
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-05-08 至 2011-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7685707
• 关键词: Address; Anus; Awareness; Behavioral; Communication; Couples; Feedback; Focus Groups; Frequencies; Gender; Gender Role; Goals; HIV; HIV Infections; HIV/STD; Happiness; Heterosexuals; Hour; Individual; Infection; Intervention; Knowledge; Latino; Life; Maintenance; Male Condoms; Measures; Modeling; Motivation; Outcome; Participant; Patient Self-Report; Phase; Pilot Projects; Prevention; Preventive Intervention; Problem Solving; Production; Puerto Rico; Randomized; Randomized Controlled Trials; Recommendation; Regression Analysis; Research; Risk; Risk Reduction; Sex Behavior; Sexual Partners; Sexuality; Social support; Staging; Testing; Training; Treatment Efficacy; Unsafe Sex; Vagina; base; behavior change; comparison group; condoms; design; efficacy testing; follow-up; high risk sexual behavior; improved; prevent; primary outcome; public health relevance; risk perception; safer sex; secondary outcome; skills; therapy design; transmission process

DESCRIPTION (provided by applicant): We propose a randomized controlled trial to adapt, implement and evaluate an intervention to prevent HIV/STI in young heterosexual Latino couples. The intervention consists of five three-hour sessions held once a week. We will use a group format to deliver the intervention with the couples. This was a successful strategy used in our previous study. The study is designed to test the impact of the modified intervention in: (1) increasing male condom use, (2) decreasing unsafe sex behaviors, (3) reducing the number of sexual partners; and (4) increasing mutual monogamy. The couples will be randomized to one of the following two conditions: (1) an HIV/STI risk reduction intervention; or (2) a life skills intervention, as control condition. The study will be carried out in two phases. Phase 1 will consist of the adaptation of an intervention designed and implemented by the PI research team. For the adaptation of the intervention we will use the ADAPT-ITT model which consists of eight phases: (1) assessment; (2) decision; (3) adaptation; (4) production; (5) topical experts; (6) integration; (7) training; and (8) testing. During this phase we will conduct focus groups, "theater testing" and a pilot of the intervention. These activities will help to explore crucial feedback and recommendations about the content of the intervention that need to be modified, according to participant's recommendations. During Phase 2 we will implement the modified intervention with 75 young heterosexual Latino couples (150 individuals) at-risk of HIV/STI infection. At this stage hierarchical modeling and mixed-effects regression analysis will be conducted to determine if the intervention accomplished the expected main outcome in increasing male condom use and decreasing unsafe sex behaviors. This project is of great relevance for public health because: (a) it will be the first known prevention intervention designed and implemented with young heterosexual Latino couples; (b) it will address previous methodological limitations by using a rigorous RCT design to test the efficacy of the intervention in increasing self-reported condom use over a 3-month follow-up period among 75 Latino couples; (c) it will test the efficacy of using a group format for the implementation of the intervention with couples; (d) it will employ a sequential approach in which couples will benefit from gender-specific sessions as well as mixed-gender sessions; and (e) it is the only known intervention with Latino couples that is based on the Information-Motivation-Behavioral Skills model of behavior change.

描述（由申请人提供）：我们提出了一项随机对照试验，以适应，实施和评估一项干预措施，以防止年轻的异性恋拉丁裔夫妇中的艾滋病毒/性传播感染。干预措施包括每周举行的五个三个小时的课程。我们将使用小组格式与夫妻进行干预。这是我们先前研究中使用的成功策略。该研究旨在测试：（1）增加男性避孕套的影响，（2）减少不安全的性行为，（3）减少性伴侣的数量； （4）增加一夫一妻制。夫妻将被随机分为以下两个条件之一：（1）HIV/STI风险降低干预；或（2）生活技能干预，作为控制条件。该研究将分为两个阶段。第1阶段将包括适应PI研究团队设计和实施的干预措施。为了适应干预措施，我们将使用由八个阶段组成的适应模型：（1）评估； （2）决定； （3）改编； （4）生产； （5）局部专家； （6）集成； （7）培训； （8）测试。在此阶段，我们将进行焦点小组，“戏剧测试”和干预措施。根据参与者的建议，这些活动将有助于探索至关重要的反馈和有关需要修改的干预措施的建议。在第2阶段，我们将与75名年轻异性恋拉丁裔夫妇（150个人）在HIV/STI感染中实施改良的干预措施。在此阶段，将进行分层建模和混合效应回归分析，以确定干预措施是否在增加男性避孕套的使用和减少不安全的性行为方面达到了预期的主要结果。该项目与公共卫生非常相关，因为：（a）它将是第一个由年轻的异性恋拉丁裔夫妇设计和实施的已知预防干预措施； （b）它将通过使用严格的RCT设计来解决以前的方法论局限性，以测试干预措施在75对拉丁裔夫妇中3个月的随访期内增加自我报告的避孕套使用的功效； （c）它将测试使用组格式与夫妻进行干预的功效； （d）它将采用一种顺序方法，其中夫妻将从性别特定的会议和混合性别会议中受益； （e）这是基于行为改变的信息动机行为技能模型的唯一已知的与拉丁裔夫妇的干预措施。