HORMONE DYNAMICS AND BONE MINERAL DENSITY IN ANOREXIA NERVOSA VS HA (SEE 0630)

神经性厌食症与 HA 的激素动态和骨矿物质密度（见 0630）

• 批准号: 7731269
• 负责人: ANNE KLIBANSKI
• 金额: $ 3.89万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-04-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7731269
• 关键词: Amenorrhea; Anorexia Nervosa; Body Composition; Bone Density; Computer Retrieval of Information on Scientific Projects Database; Disease; Funding; Grant; Hormonal; Hormonal Change; Hormones; Hypothalamic structure; Institution; Malnutrition; Research; Research Personnel; Resources; Source; United States National Institutes of Health; Woman; bone loss; hypercortisolemia

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Anorexia nervosa (AN) and hypothalamic amenorrhea (HA) are hypoestrogenic states accompanied by bone loss. The bone loss that occurs in AN is more severe than in HA, implicating an additional effect of nutritional deficiencies. Hormonal abnormalities, including hypercortisolemia, are seen in both disorders. In this study we will compare bone density, hormonal changes, and body composition in women with AN compared to women with HA and healthy controls.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 神经性厌食症（AN）和下丘脑闭经（HA）是伴有骨质流失的低雌激素状态。 AN 中发生的骨质流失比 HA 中更严重，这意味着营养缺乏的额外影响。这两种疾病均可见激素异常，包括皮质醇血症。在这项研究中，我们将比较 AN 女性与 HA 女性和健康对照女性的骨密度、荷尔蒙变化和身体成分。