FLOW CYTOMETRIC EVALUATION OF POLYFUNCTIONAL CMV-SPECIFIC T LYMPHOCYTES

多功能 CMV 特异性 T 淋巴细胞的流式细胞术评估

• 批准号: 7715469
• 负责人: Amitinder Kaur
• 金额: $ 12.98万
• 依托单位: HARVARD MEDICAL SCHOOL
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-06-05 至 2009-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7715469
• 关键词: Acquired Immunodeficiency Syndrome; Animals; CD8-Positive T-Lymphocytes; Computer Retrieval of Information on Scientific Projects Database; Cytomegalovirus; Epitopes; Evaluation; Funding; Grant; Institution; Interferon Type II; Lymphocyte; Macaca mulatta; Property; Research; Research Personnel; Resources; Source; United States National Institutes of Health; cytotoxicity

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The functional properties of rhesus cytomegalovirus (rhCMV)-specific CD8+ T lymphocytes with regards to cytotoxicity and interferon (IFN)-gamma secretion were investigated in six asymptomatic CMV-seropositive rhesus macaques. CD8+ T lymphocytes recognizing ten rhCMV epitopes, one of which was identical in three animals, were analyzed. AIDS related.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 在六种无症状的CMV-近原状疾病中，研究了有关细胞毒性和干扰素（IFN） - 甘马分泌的恒河猴巨细胞病毒（RHCMV）特异性CD8+ T淋巴细胞的功能特性。 分析了识别十种RHCMV表位的CD8+ T淋巴细胞，其中一种在三只动物中是相同的。 与艾滋病有关。