Diabetic cardiomyopathy and diastolic dysfunction: molecular mechanisms

糖尿病心肌病与舒张功能障碍：分子机制

• 批准号: 7637289
• 负责人: FRANCISCO VILLARREAL
• 金额: $ 26.11万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN DIEGO
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7637289
• 关键词: Address; Angiotensin II; Angiotensin II Receptor; Animal Model; Animals; Antibodies; Biochemical; Calcium; Cardiac; Cardiac Myocytes; Cardiovascular Diseases; Caring; Collagen; Collagen Type I; Condition; Deposition; Development; Diabetes Mellitus; Fibrillar Collagen; Fibroblasts; Fibrosis; Functional disorder; General Population; Glucose; Green Fluorescent Proteins; Heart failure; Hyperglycemia; Impairment; Incidence; Insulin Resistance; Lead; Left; Link; Measurement; Mediating; Minority; Modeling; Molecular; Mus; Non-Insulin-Dependent Diabetes Mellitus; Obesity; Patients; Phase; Physiological; Population; Production; Property; Publishing; Purpose; Rate; Relaxation; Secondary to; Testing; Time; Transgenes; Transgenic Animals; Transgenic Mice; Ventricular; Viral Vector; Work; base; crosslink; db/db mouse; design; diabetic cardiomyopathy; glycation; improved; mouse model; phospholamban; promoter; receptor; release of sequestered calcium ion into cytoplasm; reuptake; sarcoplasmic reticulum calcium ATPase; time use; transgene expression