Pilot Projects Program

试点项目计划

• 批准号: 10630581
• 负责人: DAVID E STEC
• 金额: $ 38.75万
• 依托单位: UNIVERSITY OF MISSISSIPPI MED CTR
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-07-15 至 2028-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10630581
• 关键词: Affect; American Heart Association; Appointment; Area; Basic Science; Book Chapters; Cardiorenal syndrome; Cardiovascular Diseases; Categories; Centers of Research Excellence; Clinical Research; Clinical Sciences; Communities; Conflict of Interest; Data; Development; Discipline; Education; Eligibility Determination; Equity; Evaluation; Exposure to; Extramural Activities; Faculty; Financial Support; Funding; Goals; Grant; Grant Review; Health; Individual; International; Journals; Medical center; Mentors; Metabolic Diseases; Mississippi; Paper; Phase; Pilot Projects; Population Research; Program Research Project Grants; Publishing; Research; Research Infrastructure; Research Personnel; Research Project Grants; Research Proposals; Resources; Review Committee; Scientist; Series; Services; Study Section; Testing; United States; United States National Institutes of Health; Universities; base; career; ethnic diversity; experience; gender diversity; improved; innovation; meetings; member; mid-career faculty; multidisciplinary; next generation; novel; programs; satisfaction; success; translational potential

PILOT PROJECTS PROGRAM SUMMARY/ABSTRACT The Cardiorenal and Metabolic Diseases Research Center (CMDRC) at the University of Mississippi Medical Center (UMMC) developed a highly successful Pilot Projects Program (PPP) during Phases 1 and 2 of COBRE support. Over the past 9 years, the CMDRC PPP has provided funding, mentoring, core services, and enhanced research infrastructure for 24 pilot grant investigators. The success of this program is highlighted by ~$26.92 million dollars in extramural funding obtained by previous PPP awardees as well as 459 papers published in leading journals in the field, 15 book chapters and 286 presentations at international and national meetings. To amplify the research base developed in Phases 1 and 2, the Phase 3 PPP will continue to support innovative research in the areas of cardiorenal and metabolic diseases. The PPP has four specific aims to achieve these goals: 1) To enhance the PPP developed during Phases 1 and 2, with continued emphasis on soliciting and identifying a diverse group of promising investigators whose research focuses on cardiorenal and metabolic diseases for mentoring and funding to expand the critical mass of extramurally funded CMDRC investigators; 2) To provide rigorous ongoing evaluation of the progress of individual PPP awardees and the overall PPP to maximize the impact on the investigators mentored and funded through this program; 3) To facilitate formation of new collaborative, multidisciplinary teams of investigators whose complementary expertise catalyzes the development of translational projects that result in competitive, cutting- edge multi-PI proposals for extramural funding; 4) To increase the critical mass of investigators in cardiorenal and metabolic diseases research at UMMC and to provide mentoring and funding to increase their competiveness for conducting extramurally funded basic, clinical and population research. Thus, the PPP in Phase 3 will continue to provide mentoring as well as financial and developmental support for innovative cardiorenal and metabolic diseases projects to further increase the number and diversity of funded CMDRC researchers.

试点项目计划 摘要/摘要 密西西比大学医学院心肾和代谢疾病研究中心 (CMDRC) 中心 (UMMC) 在 COBRE 第一阶段和第二阶段制定了非常成功的试点项目计划 (PPP) 支持。在过去的 9 年里，CMDRC PPP 提供了资金、指导、核心服务和 加强 24 名试点资助调查员的研究基础设施。该计划的成功体现在 历届 PPP 获奖者以及 459 篇论文获得约 2692 万美元的外部资金 在该领域的领先期刊上发表，15 个书籍章节和 286 次国际和国内演讲 会议。为了扩大第一阶段和第二阶段开发的研究基础，第三阶段PPP将继续 支持心肾和代谢疾病领域的创新研究。 PPP有四个具体内容 旨在实现以下目标： 1) 加强第一阶段和第二阶段开发的 PPP，并持续 强调招募和确定一群有前途的研究人员，他们的研究重点是 心肾和代谢疾病的指导和资助，以扩大壁外的临界质量 资助 CMDRC 调查员； 2) 对个别 PPP 的进展提供严格的持续评估 获奖者和整个 PPP 最大限度地提高对通过此项目指导和资助的研究人员的影响 程序; 3) 促进新的协作性、多学科研究团队的形成，其 互补的专业知识促进转化项目的发展，从而产生具有竞争力的、前沿的 外部资金的边缘多PI提案； 4) 增加心肾研究人员的临界数量 UMMC 和代谢疾病研究，并提供指导和资金以提高他们的能力 进行校外资助的基础、临床和人群研究的竞争力。因此，PPP 在 第三阶段将继续为创新型企业提供指导以及财务和发展支持 心肾和代谢疾病项目进一步增加资助的CMDRC的数量和多样性 研究人员。