BIOTECHNOGY: PATHWAYS TO DISEASE PREVENTION AND THERAPY (BPDPT)

生物技术：疾病预防和治疗途径 (BPDPT)

• 批准号: 7959138
• 负责人: CARL B GOODMAN
• 金额: $ 41.05万
• 依托单位: FLORIDA AGRICULTURAL AND MECHANICAL UNIV
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-06-01 至 2010-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7959138
• 关键词: Biomedical Research; Biotechnology; Cessation of life; Collaborations; Comet Assay; Computer Retrieval of Information on Scientific Projects Database; Core Facility; DNA; DNA Damage; DNA Repair; Development; Environment; Equipment; Faculty; Florida; Flow Cytometry; Fostering; Funding; Genomics; Goals; Grant; Human Resources; Institution; Mission; Molecular Biology; Pathway interactions; Pharmacologic Substance; Postdoctoral Fellow; Prevention therapy; Protein Analysis; Proteomics; RNA analysis; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Retirement; Science; Scientist; Services; Source; Structure; Technical Expertise; Technology; Time; Training; United States National Institutes of Health; Universities; Western Blotting; abstracting; disorder prevention; experience; gel electrophoresis; professor; skills

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Changes: Due to the untimely death of Dr. Ronald Thomas (BPDPT Activity Leader) and the retirement of Dr. Ann Heiman (Faculty Advisor for Flow Cytometry Facility), the BPDPT has experienced a change in its organization. Dr. Carl Goodman, Professor, Basic Pharmaceutical Sciences, serves as the BPDPT Core Leader. He is a very experienced researcher with outstanding managerial skills, has assumed the responsibilities as Activity Leader for the BPDPT Core. The BPDPT Biotechnology Core has reorganized the research structure with the appropriate personnel: Genomics Coordinator: Dr. Carl Goodman Proteomics Coordinator: Dr. Nazarius Lamango & Dr. Selina Darling-Reed Flow Cytometry Coordinator: Dr. Ebenezer Oriaku & Dr. Selina Darling-Reed DNA Damage and Repair Coordinator: Dr. Barack Abonyo. Faculty Research Scientist: Dr. Selina Darling-Reed Research Associates: Drs. Ramesh Badisa and Equar Taka and will provide the service in Flow Cytometry and Proteomics application in Pharmaceutical Sciences. ABSTRACT The Biotechnology: Pathways to Disease Prevention and Therapy (BPDPT) is an expansion of the previously funded molecular biology research activity. Its' continuing mission is to provide the university biomedical research investigators with contemporary molecular biology technology and technical expertise. This will strengthen the research infrastructure at Florida A & M University. The long-term goal of this effort is to establish Informational and technical resources that will result in increased molecular biology expertise of the research faculty, continual investigator collaborations, and foster new biomedical research collaborative ventures. Development of the BPDPT will also increase new faculty recruitment opportunities at Florida A & M University. To complete these goals the following specific aims have been identified: 1) Establish the equipment infrastructure needed for molecular biology research; 2) Develop a University wide collaborative environment for biomedical research investigators; 3) Facilitate avenues by which Faculty can receive molecular biology training; and 4) Increase the number of investigators involved in molecular biology research. Currently we have established traditional molecular biology technology including real-time PCR; western blot analysis; protein, DNA, & RNA analysis via gel electrophoresis; DNA damage analysis via the COMET assay, and flow cytometry. In the proposed activity we plan to expand the molecular biology expertise to include proteomics and genomics. Ultimately, we plan to expand the molecular biology research activity to a full functioning self-sustaining core facility. Overall, the BPDPT will serve to establish beneficial resources that will result in increased molecular biology expertise of the research Faculty, continual investigator collaborations, and foster new biomedical research collaborative ventures and strengthens the research infrastructure at Florida A & M University. Supported by NIH/NCRR/RCMI G12RR03020.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 更改： 由于Ronald Thomas博士（BPDPT活动负责人）和Ann Heiman博士（流式细胞仪设施的教职顾问）的退休，BPDPT的组织发生了变化。 基础制药科学教授卡尔·古德曼（Carl Goodman）博士是BPDPT核心领导者。 他是一位经验丰富的研究人员，具有出色的管理技能，他担任了BPDPT核心的活动领导者的责任。 BPDPT生物技术核心已与适当的人员重组研究结构： 基因组学协调员：卡尔·古德曼博士 蛋白质组学协调员：Nazarius Lamango博士和Selina Darling-Reed博士 流式细胞仪协调员：Ebenezer Oriaku博士和Selina Darling-Reed博士 DNA损坏和维修协调员：Barack Abonyo博士。 教师研究科学家：Selina Darling-Reed博士 研究伙伴：Drs。 Ramesh Badisa和Equar Taka，将在药物科学中提供流式细胞仪和蛋白质组学应用中的服务。 抽象的 生物技术：预防疾病和治疗途径（BPDPT）是先前资助的分子生物学研究活动的扩展。它的持续任务是为大学生物医学研究人员提供当代分子生物学技术和技术专长。这将加强佛罗里达农工大学的研究基础设施。这项工作的长期目标是建立信息和技术资源，从而导致研究教师，持续研究者合作的分子生物学专业知识，并培养新的生物医学研究合作企业。 BPDPT的发展还将增加佛罗里达州A＆M大学的新教师招聘机会。为了完成这些目标，已经确定了以下特定目标：1）建立分子生物学研究所需的设备基础设施； 2）为生物医学研究研究人员开发大学广泛的协作环境； 3）促进教师可以接受分子生物学培训的途径； 4）增加参与分子生物学研究的研究者的数量。目前，我们已经建立了包括实时PCR在内的传统分子生物学技术； Western印迹分析；蛋白质，DNA和RNA分析通过凝胶电泳分析；通过彗星测定和流式细胞仪进行DNA损伤分析。在提出的活动中，我们计划将分子生物学专业知识扩展到包括蛋白质组学和基因组学。 最终，我们计划将分子生物学研究活动扩展到一个完整的自我维持核心设施。 总体而言，BPDPT将有助于建立有益的资源，从而导致研究教师的分子生物学专业知识，持续的研究者合作，并促进新的生物医学研究合作企业，并加强佛罗里达A＆M大学的研究基础设施。由NIH/NCRR/RCMI G12RR03020支持。