Community-Engaged Research on COVID-19 Testing Among Underserved and/or Vulnerable Populations Phase II

社区参与的针对服务不足和/或弱势群体的 COVID-19 检测研究第二阶段

• 批准号: 10544758
• 负责人: Marianna K Baum
• 金额: $ 110.58万
• 依托单位: FLORIDA INTERNATIONAL UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-01-01 至 2024-11-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10544758
• 关键词: Affect; Antibodies; Antibody Formation; Anxiety; Area; Attitude; Behavior; Belief; Black Populations; Black race; CLIA certified; COVID-19; COVID-19 disparity; COVID-19 pandemic; COVID-19 prevention; COVID-19 risk; COVID-19 stress; COVID-19 testing; COVID-19 vaccine; Caring; Case Fatality Rates; Cessation of life; Church; Clinic; Common Data Element; Communities; Community Outreach; Community Participation; Complex; Contact Tracing; County; Data; Data Analyses; Economics; Effectiveness; Environmental Risk Factor; Epidemic; Event; Faith; Faith leader; Florida; Goals; Health; Health Personnel; Healthcare; Hispanic; Hispanic Populations; Hospitalization; Hour; Incidence; Individual; Inequity; Infection; Infrastructure; Interview; Knowledge; Laboratories; Leadership; Longitudinal Studies; Measurable; Mental Depression; Mental Health; Minority; Minority Groups; Neighborhoods; Nurses; Outcome; Participant; Phase; Physicians; Play; Population; Psyche structure; Public Health; Questionnaires; RADx Underserved Populations; Research; Resources; SARS-CoV-2 infection; SARS-CoV-2 transmission; Serology; Seroprevalences; Site; Social Conditions; Social status; Source; Surveys; Testing; Underserved Population; United States; Vaccination; Vaccines; Variant; Vulnerable Populations; community engaged research; community engagement; community organizations; community partnership; community transmission; data mining; disparity reduction; ethnic minority; experience; fighting; follow-up; health disparity; hispanic community; improved; member; minority communities; minority health; minority healthcare; outreach; pandemic disease; phase 1 study; poor health outcome; racial minority; recruit; resilience; response; social health determinants; social vulnerability; testing uptake; trustworthiness; underserved community; uptake; vaccine acceptance; vaccine access; vaccine trial; vulnerable community

PROJECT SUMMARY The COVID-19 pandemic has caused unprecedented public health and economic consequences globally and in the United States. Long-standing social inequities have been magnified and vulnerable communities have been disproportionately burdened by the pandemic. In Miami-Dade County, Florida, where minority populations experience a high level of social vulnerability, Blacks and Hispanics are overrepresented in COVID-19 related hospitalizations and deaths compared to national rates. Further, Miami-Dade County continues to experience COVID-19 rates well above the state and national levels. Effective vaccines are now available, yet vaccination rates have been persistently lower among U.S. minorities, broadening disparities in COVID-19 outcomes. As such, expanded SARS-CoV-2 testing and vaccine acceptance is critical to mitigating community spread in underserved and vulnerable communities. In this application for Phase II of the RADx-UP project, we will apply the knowledge gained during Phase I to expand community outreach to increase testing and vaccine uptake in minority communities to decrease disparities that contribute to burden of COVID-19 in underserved and vulnerable populations. We propose to continue our RADx-UP community-engaged research by employing new recruitment strategies in conjunction with four community partners to increase reach of testing that include engaging faith leaders and minority health care providers, and placing our mobile testing (and vaccination) unit in church parking areas. We will also conduct a longitudinal study among participants who completed Phase I of the study to assess (a) changes in infection and vaccination status, (b) how the availability of vaccines affects attitudes, beliefs, and behaviors related to testing, (c) changes in SDoH and their impact on COVID-19 testing and vaccine uptake/hesitancy, and (d) the relationship between mental resilience, mental health, and testing and vaccine uptake/hesitancy, and (e) other RADx-UP common data elements. We will also conduct post-infection and post-vaccination studies on antibody production and subsequent infections. For the proposed Phase II application, we have partnered with new community organizations, including Keeping the Faith to Fight COVID-19, an organization of minority health care providers working with Black and Black Hispanic churches, and with the Community Engagement Alliance (CEAL) Against COVID-19 Disparities initiative. We are currently conducting RADx-UP Phase I with established infrastructure and community partnerships to accomplish the aims and enable rapid and measurable impact in access and uptake of SARS- CoV-2 testing by underserved and vulnerable populations. Our community partners have the resources to provide community engagement, public health mitigation, and follow-up care for cases who test positive. Our strategy includes Scientific and Community Advisory Boards; a mobile testing unit; a CLIA-licensed laboratory headed by the PI of this application; data mining and longitudinal approaches for data analyses; and a research team experienced in recruiting and retaining members of the communities targeted in this proposal.

项目概要 COVID-19 大流行在全球范围内造成了前所未有的公共卫生和经济后果 在美国。长期存在的社会不平等现象被放大，弱势群体也受到影响 因疫情而承受了不成比例的负担。在佛罗里达州迈阿密戴德县，少数族裔人口 经历高度社会脆弱性，黑人和西班牙裔在与 COVID-19 相关的群体中所占比例过高 住院人数和死亡人数与全国比率相比。此外，迈阿密戴德县继续经历 COVID-19 的发病率远高于州和国家水平。现在已经有了有效的疫苗，但尚未接种疫苗 美国少数族裔的感染率持续较低，导致 COVID-19 结果的差异扩大。作为 因此，扩大 SARS-CoV-2 检测和疫苗接受对于减轻社区传播至关重要 服务不足和脆弱的社区。在 RADx-UP 项目第二阶段的申请中，我们将申请 在第一阶段中获得的知识，以扩大社区外展，以增加检测和疫苗接种 少数族裔社区减少因服务不足和服务不足而造成的 COVID-19 负担的差异 弱势群体。我们建议继续我们的 RADx-UP 社区参与研究 与四个社区合作伙伴合作的新招募策略，以扩大测试范围，其中包括 让信仰领袖和少数族裔医疗保健提供者参与进来，并放置我们的移动检测（和疫苗接种）单位 在教堂停车场。我们还将对完成第一阶段的参与者进行纵向研究 研究的目的是评估（a）感染和疫苗接种状况的变化，（b）疫苗的可用性如何 影响与测试相关的态度、信念和行为，(c) SDoH 的变化及其对 COVID-19 的影响 测试和疫苗接种/犹豫，以及 (d) 心理弹性、心理健康和 测试和疫苗接种/犹豫，以及 (e) 其他 RADx-UP 通用数据元素。我们还将进行 关于抗体产生和随后感染的感染后和疫苗接种后研究。对于 拟议的第二阶段申请，我们与新的社区组织合作，包括 Keeping the Faith to Fight COVID-19，一个由少数族裔医疗保健提供者组成的组织，与 Black and Black 合作 西班牙裔教会以及社区参与联盟 (CEAL) 反对 COVID-19 差异 倡议。我们目前正在利用已建立的基础设施和社区进行 RADx-UP 第一阶段 伙伴关系，以实现这些目标，并在 SARS 的获取和吸收方面产生快速和可衡量的影响 由服务不足和弱势群体进行 CoV-2 检测。我们的社区合作伙伴拥有资源 为检测呈阳性的病例提供社区参与、公共卫生缓解和后续护理。我们的 战略包括科学和社区咨询委员会；移动测试装置； CLIA 许可的实验室 由本应用程序的 PI 领导；数据挖掘和纵向数据分析方法；和一个 研究团队在招募和留住本提案所针对的社区成员方面经验丰富。

项目成果

Community-Engaged Research: COVID-19 Testing, Infection, and Vaccination among Underserved Minority Communities in Miami, Florida.

社区参与研究：佛罗里达州迈阿密服务不足的少数族裔社区的 COVID-19 检测、感染和疫苗接种。

• 发表时间: 2024-01-24
• 影响因子: 7.8
• 作者: Martin, Haley R;Brown, David R;Fluney, Eileen;Trepka, Mary Jo;Marty, Aileen M;Roldan, Eneida O;Liu, Qingyun;Barbieri, Manuel A;Baum, Marianna K
• 通讯作者: Baum, Marianna K

Detection of SARS-CoV-2 in high-efficiency particulate air (HEPA) filters of low-cost air purifiers in community-based organizations.

在社区组织的低成本空气净化器的高​​效颗粒空气 (HEPA) 过滤器中检测 SARS-CoV-2。

• 发表时间: 2023-10-14
• 影响因子: 3
• 作者: Clarke, Rachel D;Garba, Nana Aisha;Barbieri, Manuel A;Acuna, Leonardo;Baum, Marianna;Rodriguez, Maribel Saad;Frias, Hansel;Saldarriaga, Paulina;Stefano, Troy;Mathee, Kalai;Narasimhan, Giri;R Brown, David
• 通讯作者: R Brown, David

Disability and COVID-19: Challenges, testing, vaccination, and postponement and avoidance of medical care among minoritized communities.

残疾和 COVID-19：少数群体社区中的挑战、检测、疫苗接种以及推迟和避免医疗护理。

• 发表时间: 2024-04
• 作者: Martin, Haley R;Hu, Nan;Liu, Qingyun;Bastida Rodriguez, Jose A;Gieseken, Stephanie;Johnson, Angelique;Enrione, Evelyn;Trepka, Mary Jo;Brown, David R;Marty, Aileen M;Sales Martinez, Sabrina;Campa, Adriana;Roldan, Eneida O;Hernandez Suarez, Yol
• 通讯作者: Hernandez Suarez, Yol