Administrative Core
行政核心
基本信息
- 批准号:10540725
- 负责人:
- 金额:$ 6.42万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2018
- 资助国家:美国
- 起止时间:2018-12-06 至 2024-11-30
- 项目状态:已结题
- 来源:
- 关键词:AccountingAchievementAffinityAgreementAnti-Idiotypic AntibodiesAntibodiesAntigensB-Cell Antigen ReceptorB-LymphocytesBudgetsCollaborationsCommunicationDataDedicationsDevelopmentEnsureEvolutionExpenditureFrequenciesFundingGenerationsGoalsGrantHIV-1HumanIACUCImmune systemImmunizationIndividualInfrastructureInstitutionKnock-in MouseLeadershipLegalMonitorMusParticipantPoliciesPolicy CompliancePreparationPrincipal InvestigatorProgress ReportsProtocols documentationPublicationsQuality ControlReagentRegulationRegulatory AffairsReportingResearchResearch ActivityResearch PersonnelResearch Project GrantsResolutionResourcesSchemeScientific EvaluationSiteStructureStructure of germinal center of lymph nodeTestingUnited States National Institutes of Healthcohesiondesignexperimental studyin vivointer-institutionalmaterial transfer agreementmeetingsneutralizing antibodyprogramsreceptorrecruitrepositorysuccesstool
项目摘要
PROJECT SUMMARY / ABSTRACT
The Administrative Core (Core A) will support the scientific and programmatic activities of our HIVRAD
Program and provide the necessary infrastructure for the Program to achieve its overall research objectives
and milestones in the most efficient and effective manner. Core A has the following specific aims: (1) to provide
scientific leadership and coordination of the HIVRAD’s activities, assuring achievement of our scientific goals
while maximizing scientific collaboration; (2) to optimize communication among the participating scientific
investigators; and between Project Leaders, the Scientific Advisory Board, and the NIH Program Officer; and
(3) to provide fiscal oversight, administrative support, and ensure regulatory and grant policy compliance. Core
A will be led by the Principal Investigator, Dr. Leonidas Stamatatos, who will manage, oversee and coordinate
the efforts of each participant in the Program, with the assistance of the Project Manager. A group of external
Scientific Advisors will be formed to oversee the scientific activities of the HIVRAD and provide advice and
support. This Core will oversee and integrate the execution of the research Projects and Scientific Core. Core
A oversees all aspects of this Program including scientific issues, regulatory affairs, finance, communication,
coordination and administration of each of the Cores and Projects. This Core will ensure that expenditures and
projections are commensurate with the goals of the overall project; monitor the fiscal and functional aspects of
all subcontracts; and coordinate with the Offices of Sponsored Research at participating Institutions for the
disbursement, expenditure and accounting of grant funds. This Core will coordinate the preparation and
submission of scientific and financial reports, facilitate the establishment of regulatory protocols and ensure
regulatory compliance. Communications will be facilitated utilizing a variety of tools, including a dedicated,
external SharePoint site, which will serve as a centralized repository for Program data, regulatory compliance
documents, inter-institutional and material transfer agreements and relevant publications, abstracts and
presentations.
项目概要/摘要
行政核心(核心 A)将支持我们的 HIVRAD 的科学和计划活动
为该计划制定计划并提供必要的基础设施,以实现其总体研究目标
核心 A 具有以下具体目标: (1) 提供
HIVRAD 活动的科学领导和协调,确保实现我们的科学目标
(2) 优化参与科研人员之间的交流
研究人员、项目负责人、科学顾问委员会和 NIH 项目官员之间;
(3) 提供财政监督、行政支持,并确保监管和补助政策的合规性。
A 将由首席研究员 Leonidas Stamatatos 博士领导,他将管理、监督和协调
在一组外部项目经理的协助下,该计划的工作。
将成立科学顾问来监督 HIVRAD 的科学活动并提供建议和
该核心将监督和整合研究项目和科学核心的执行。
A 监督该计划的各个方面,包括科学问题、监管事务、财务、沟通、
每个核心和项目的协调和管理 该核心将确保支出和
预测与整个项目的目标相一致;监测财政和职能方面的情况;
所有分包合同;并与参与机构的赞助研究办公室进行协调
该核心将协调赠款资金的支付、支出和会计。
提交科学和财务报告,促进制定监管协议并确保
将利用各种工具促进通信,包括专用的、
外部 SharePoint 站点,将作为计划数据、法规遵从性的集中存储库
文件、机构间和材料转让协议以及相关出版物、摘要和
演示文稿。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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Leonidas Stamatatos其他文献
Leonidas Stamatatos的其他文献
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{{ truncateString('Leonidas Stamatatos', 18)}}的其他基金
Guiding the maturation of anti-CD4-BS bnAbs through sequential heterologous Env immunization
通过序贯异源 Env 免疫指导抗 CD4-BS bnAb 的成熟
- 批准号:
10849963 - 财政年份:2023
- 资助金额:
$ 6.42万 - 项目类别:
Self-amplifying mRNA-based vaccines to elicit VRC01-class bnAbs
基于 mRNA 的自我扩增疫苗可引发 VRC01 级 bnAb
- 批准号:
10589641 - 财政年份:2023
- 资助金额:
$ 6.42万 - 项目类别:
Expansion and targeted maturation of germline HIV-1 bNAb-associated BCRs
种系 HIV-1 bNAb 相关 BCR 的扩增和靶向成熟
- 批准号:
10540724 - 财政年份:2018
- 资助金额:
$ 6.42万 - 项目类别:
Expansion and targeted maturation of germline HIV-1 bNAb-associated BCRs
种系 HIV-1 bNAb 相关 BCR 的扩增和靶向成熟
- 批准号:
10593443 - 财政年份:2018
- 资助金额:
$ 6.42万 - 项目类别:
Development of prime-boost immunization schemes to elicit VRC01-class bNAbs in polyclonal human BCR backgrounds
开发初免-加强免疫方案以在多克隆人 BCR 背景中引发 VRC01 类 bNAb
- 批准号:
10540729 - 财政年份:2018
- 资助金额:
$ 6.42万 - 项目类别:
Expansion and targeted maturation of germline HIV-1 bNAb-associated BCRs
种系 HIV-1 bNAb 相关 BCR 的扩增和靶向成熟
- 批准号:
10300438 - 财政年份:2018
- 资助金额:
$ 6.42万 - 项目类别:
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