Data Resource Core

数据资源核心

• 批准号: 10513122
• 负责人: Adam Cain Resnick
• 金额: $ 124.03万
• 依托单位: CHILDREN'S HOSP OF PHILADELPHIA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-26 至 2025-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10513122
• 关键词: Address; Adoption; Artificial Intelligence; Automation; Automobile Driving; Big Data; Childhood; Clinical; Clinical Data; Communities; Computer software; Data; Data Analyses; Data Scientist; Data Set; Databases; Development; Disease; Family member; Fast Healthcare Interoperability Resources; Feedback; Foundations; Future; Genes; Genetic Predisposition to Disease; Growth; Infrastructure; Language; Leadership; Machine Learning; Maintenance; Malignant Childhood Neoplasm; Malignant Neoplasms; Metadata; Monitor; Patients; Pattern; Research; Research Personnel; Resources; Secure; Services; Structural Congenital Anomalies; Sustainable Development; Techniques; Technology; Time; Trust; United States National Institutes of Health; Variant; Work; analytical tool; base; cloud based; cloud platform; cohort; cost; data access; data interoperability; data management; data portal; data resource; database of Genotypes and Phenotypes; empowered; genetic variant; genomic data; improved; innovation; interoperability; light weight; open data; open source; programs; support tools; tool; virtual

PROJECT SUMMARY The Kids First Data Resource Core (DRC) provides the community facing portal, cloud-based workspace (CAVATICA), and analytic tools that support analysis and scientific discovery utilizing Kids First Data as provisioned by the Kids First Data Coordinating Core (DCC). The aims of this project expand and improve upon the existing Kids First Data Portal Core to provide a wider scope of data resources to the community to support analysis and scientific discovery. The Kids First Portal provides researchers, clinicians, data scientists, patients, and their family members with a fully functional database to explore, build virtual cohorts, and analyze clinical and genomic data. As part of this project, the portal will be expanded to include advanced cohort building and search capabilities, including genes and variants as well as new analytic capabilities. The portal and CAVATICA will have new integrations, such as the variant workbench and deployment of lightweight scientific applications to better empower a wide range of users. The DRC will also work towards understanding new and emerging opportunities to support artificial intelligence and machine learning (AI/ML) techniques and workflows. To enable the broadest use of Kids First data, the DRC is committed to interoperability and will leverage standards such as GA4GH DRS, NIH Research Auth Service, Common Workflow Language, FHIR and other emerging standards across the NIH data landscape.

项目概要 Kids First 数据资源核心 (DRC) 提供面向社区的门户、基于云的工作区 (CAVATICA) 以及支持利用 Kids First Data 进行分析和科学发现的分析工具 由 Kids First 数据协调核心 (DCC) 提供。该项目的目标扩展并改进 现有的 Kids First 数据门户核心为社区提供更广泛的数据资源以支持 分析和科学发现。 Kids First Portal 为研究人员、临床医生、数据科学家、患者、 及其家庭成员使用功能齐全的数据库来探索、建立虚拟队列并分析临床 和基因组数据。作为该项目的一部分，该门户将进行扩展，以包括高级队列建设和 搜索能力，包括基因和变异以及新的分析能力。门户网站和 CAVATICA 将有新的集成，例如变体工作台和轻量级科学应用程序的部署 更好地赋能广大用户。刚果民主共和国还将努力了解新的和正在出现的 支持人工智能和机器学习 (AI/ML) 技术和工作流程的机会。启用 为了最广泛地使用“儿童优先”数据，DRC 致力于互操作性，并将利用以下标准： GA4GH DRS、NIH 研究授权服务、通用工作流程语言、FHIR 和其他新兴标准 整个 NIH 数据格局。