SCGE Administrative Supplement

SCGE行政补充

• 批准号: 10651526
• 负责人: DENNIS J. HARTIGAN-O'CONNOR
• 金额: $ 18.74万
• 依托单位: UNIVERSITY OF CALIFORNIA AT DAVIS
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-06-27 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10651526
• 关键词: Address; Administrative Supplement; California; Center for Translational Science Activities; Clinical Sciences; Collaborations; Communities; Ensure; Equipment; Evaluation; Fostering; Future; Genome; Infrastructure; Primates; Research; Research Personnel; Resources; Service provision; Technology; Testing; Translations; genome editing; human disease; nonhuman primate; somatic cell gene editing; support tools; synergism; tool

PROJECT SUMMARY / ABSTRACT The Nonhuman Primate Testing Center for Evaluation of Somatic Cell Genome Editing Tools supports studies with nonhuman primates that will advance the genome editing field, and significantly contributes to the future translation of these technologies for the treatment of human disease. The Nonhuman Primate Testing Center includes a robust team and partnerships that capitalize on major strengths including the California National Primate Research Center, Genome Center, and Clinical and Translational Science Center. The Nonhuman Primate Testing Center offers state-of-the-art capabilities for Somatic Cell Genome Editing (SCGE) awardees to conduct high quality research in nonhuman primates. The Testing Center leverages a supportive framework that has demonstrated a long-standing commitment to providing research opportunities and collaborations to investigators nationwide. Through this powerful infrastructure the Testing Center fosters partnerships with SCGE awardees through provision of expertise, resources, and collaborative opportunities that accelerate their research, and ensures synergism across the SCGE Consortium and with ongoing interactions with the Dissemination and Coordinating Center. This supplement provides equipment that addresses the basic functions of the Testing Center and the provision of services to investigators across the SCGE Consortium.

项目概要/摘要 非人类灵长类动物体细胞基因组编辑工具评估测试中心支持研究 与非人类灵长类动物合作将推动基因组编辑领域的发展，并对未来做出重大贡献 将这些技术转化为治疗人类疾病。非人类灵长类动物测试中心 包括强大的团队和合作伙伴关系，充分利用包括加州国家队在内的主要优势 灵长类动物研究中心、基因组中心以及临床和转化科学中心。非人类 灵长类动物测试中心为体细胞基因组编辑 (SCGE) 获奖者提供最先进的能力 对非人类灵长类动物进行高质量的研究。测试中心利用支持框架 这表明了对提供研究机会和合作的长期承诺 全国调查人员。通过这一强大的基础设施，测试中心与以下机构建立了合作伙伴关系： SCGE 获奖者通过提供专业知识、资源和合作机会来加速他们的发展 研究，并确保整个 SCGE 联盟的协同作用以及与 传播和协调中心。本补充提供了解决基本问题的设备 测试中心的职能以及为整个 SCGE 联盟的研究人员提供服务。