Administrative Core

行政核心

• 批准号: 10327461
• 负责人: Sanjiv J Shah
• 金额: $ 166.45万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-13 至 2026-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10327461
• 关键词: Artificial Intelligence; Award; Biological; Cardiology; Cardiovascular Diseases; Cardiovascular system; Clinical Data; Clinical Investigator; Clinical Trials; Cohort Studies; Collaborations; Complex; Data; Data Analyses; Data Collection; Data Coordinating Center; Data Scientist; EFRAC; Electronic Health Record; Enrollment; Ensure; Equipment; Fellowship Program; Follow-Up Studies; Funding; Genome; Goals; Greenland; Heart; Heart failure; Human Resources; Industry; Infrastructure; Institutes; International; Laboratories; Lead; Leadership; Medicine; Mentors; Modeling; Monitor; Multicenter Studies; National Heart, Lung, and Blood Institute; Observational Study; Patients; Phenotype; Postdoctoral Fellow; Process; Protocols documentation; Records; Research; Research Personnel; Resources; Site; Source; Standardization; Syndrome; Trans-Omics for Precision Medicine; Translations; United States National Institutes of Health; Universities; augmented intelligence; base; clinical center; computer science; data acquisition; data repository; data standards; design; epidemiology study; experience; follow-up; health data; innovation; mHealth; outreach; participant enrollment; phenome; preservation; programs; prospective; skills; skills training; synergism

PROJECT SUMMARY The Northwestern HeartShare Data Translation Center (DTC), leverages processes, personnel, and infrastructure from the Northwestern University (NU) Data Analysis and Coordinating Center (NUDACC), to have the staffing, equipment, and other resources available to ensure that the Administrative and Outreach Core meets its goals of (1) designing, implementing, and integrating the HeartShare program components; (2) coordinating and optimizing the data ascertainment from the electronic health records (EHRs) at the HeartShare Clinical Centers (CCs); (3) ensuring successful enrollment and retention of heart failure (HF) patients and controls for the prospective component of HeartShare; (4) supporting a call center and integrating with the Eureka platform, which will facilitate acquisition of mobile health data and contact with patients; (5) providing consistency and standardization of data acquisition across the CCs and establishing core laboratories; and (6) developing a Research Skills Program, which will be modeled after Northwestern’s innovative Computer Science-X (CS-X) Program, which has successfully bridged the divide between cardiology fellows and post-doctoral data scientists via integration with Northwestern Bluhm Cardiovascular Institute’s Center for Artificial Intelligence in Cardiovascular Medicine Fellowship Program. The HeartShare DTC Administrative and Outreach Core also leverages the resources of the Institute for Augmented Intelligence in Medicine (I.AIM) at Northwestern. The HeartShare Administrative/Outreach Core is designed to complete the following specific aims. (1) To design, implement, and coordinate the HeartShare program components to ensure the successful completion of the retrospective and prospective aspects of the program. We aim to provide guidance to sites and monitor metrics for HFpEF patient enrollment, engagement, and retention; ensure data consistency and standardization across sites; and provide administrative, financial, and scientific leadership of HeartShare. (2) To create a state-of-the- art HeartShare Call Center integrated with the Eureka platform that will facilitate acquisition of mobile health data, outside records, and longitudinal contact with patients, which will be essential for developing a comprehensive HeartShare data repository and will facilitate longitudinal follow-up. (3) To create an innovative Research Skills Program that will provide high-quality mentoring and synergy for early-stage clinical investigators and data scientists using the successful Northwestern CS-X program as a blueprint.

项目概要 西北 HeartShare 数据翻译中心 (DTC) 利用流程、人员和 西北大学 (NU) 数据分析和协调中心 (NUDACC) 的基础设施， 人员配备、设备和其他可用资源，以确保行政和外展核心 实现 (1) 设计、实施和集成 HeartShare 程序组件 (2) 的目标； 协调和优化 HeartShare 电子健康记录 (EHR) 的数据确定 临床中心 (CC)；(3) 确保心力衰竭 (HF) 患者的成功入组和保留 对 HeartShare 的预期组件的控制 (4) 支持呼叫中心并与 Eureka 集成； 平台，这将有利于移动健康数据的获取和与患者的联系；（5）提供一致性； 跨 CC 的数据采集标准化并建立核心实验室；(6) 开发一个 研究技能计划，将以西北大学创新的计算机科学-X (CS-X) 为蓝本 该计划成功弥合了心脏病学研究员和博士后数据科学家之间的鸿沟 通过与西北布鲁姆心血管研究所的人工智能中心整合 HeartShare DTC 管理和外展核心项目也是心血管医学奖学金计划。 利用西北大学医学增强智能研究所 (I.AIM) 的资源。 HeartShare 管理/外展核心旨在完成以下具体目标 (1) 设计、 实施并协调 HeartShare 计划组件，以确保成功完成 我们旨在为网站提供指导并监控指标。 HFpEF 患者登记、参与和保留；确保整个数据的一致性和标准化 (2) 创造一个最先进的状态 art HeartShare 呼叫中心与 Eureka 平台集成，将促进移动医疗的获取 数据、外部记录以及与患者的纵向接触，这对于制定 全面的 HeartShare 数据存储库并将促进纵向跟进 (3) 创建创新。 研究技能计划将为早期临床研究人员提供高质量的指导和协同作用 和数据科学家以成功的西北大学 CS-X 项目为蓝图。