Developmental Research Program

发展研究计划

• 批准号: 7507424
• 负责人: MICHAEL G BRATTAIN
• 金额: $ 4.94万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7507424
• 关键词: Achievement; Address; Advisory Committees; Award; Basic Science; Budgets; Conflict (Psychology); Consultations; Development; Diagnostic; Early Diagnosis; Elements; Faculty; Funding; Goals; Grant; Human; Institution; Intervention; Malignant neoplasm of pancreas; Medical center; Nebraska; Nursing Faculty; Pancreatic carcinoma; Pilot Projects; Prevention; Principal Investigator; Process; Reproduction spores; Request for Proposals; Research; Research Personnel; Research Project Grants; Scientist; Staging; Study Section; Therapeutic; Time; Translational Research; UNMC Eppley Cancer Center; Universities; Wages; anticancer research; base; innovation; member; novel; programs; success

The principal goal of the Developmental Research Program is to fund promising early stage projects that address important translational objectives in prevention, early detection, and therapy of pancreatic carcinoma. Our principal intent for Developmental Research Program is to bring novel translational research projects to the SPORE program. Key elements that determine priority in this program are innovation, novelty, and potential for success in translational pancreatic cancer research. All Developmental Funds will be awarded by competition based on submission of a NIH-style pilot project application. There is a requirement for clear evidence that the proposed project shows potential of developing into a larger research project that will involve human intervention for pancreatic cancer (diagnostic or therapeutic). We will have available a minimum of $175,000 a year ($100,000 from the SPORE grant and $75,000 a year in matching funds from the UNMC/Eppley Cancer Center), which will be used to fund 2 projects. We will accept applications from single investigators for focused projects with budgets of up to $87,500 or larger collaborative projects involving two or more investigators with budgets of up to $175,000. Proposals are received and processed by the Administrative Core. Once a year, a request for proposals (RFP) is developed by the Principal Investigator and distributed to all faculty at the University of Nebraska Medical Center, Creighton University, the University of Nebraska at Omaha, the University of Nebraska at Lincoln, University of Nebraska at Kearny, collaborating faculty at other institutions, and faculty members at other Institutions who have contacted us or have been identified by the SPORE Scientific Council, Internal Advisory Board, or External Advisory Committee as potential collaborators on existing projects or developers of important new SPORE projects related to pancreatic cancer. Two types of applications will be solicited. Applications from single investigators for focused projects with budgets of up to $87,500 per year, or larger collaborative translational projects involving two or more investigators with budgets of up to $175,000 per year. Applications are reviewed by a study section comprised of the Internal Advisory Board, members of the SPORE program who are not in conflict, selected scientists and clinicians from the UNMC Eppley Cancer Center. Final selection of the funded applications is made by the External Advisory Board, who acts as a Advisory Council, in consultation with Dr. Brattain and Dr. Grem, who are the administrative leaders of the Developmental Research Program. Funded projects must have a set of quantifiable milestones for achievement that represent acceptable progress by the end of the first year.

发展研究计划的主要目标是为有希望的早期项目提供资金 解决胰腺预防，早期检测和治疗方面的重要翻译目标 癌。我们的发展研究计划的主要意图是带来新颖的翻译研究 孢子计划的项目。确定此计划优先级的关键要素是创新， 新颖性，以及在翻译胰腺癌研究中取得成功的潜力。所有发展资金将 根据提交NIH风格的试点项目申请的竞争授予。有一个 明确的证据的要求表明，拟议的项目表明了发展为更大的研究的潜力 将涉及胰腺癌干预的项目（诊断或治疗性）。我们将有 每年至少可获得$ 175,000（从孢子赠款中获得100,000美元，每年$ 75,000 UNMC/Eppley癌症中心的资金），该中心将用于2个项目。我们会接受的 单个调查人员的申请针对重点项目的预算高达87,500美元或更高 合作项目涉及两个或更多的调查人员，预算高达17.5万美元。建议是 由行政核心接收和处理。每年一次，提案请求（RFP）是 由首席研究员开发，并分发给内布拉斯加大学医学大学的所有教师 中心，克雷顿大学，内布拉斯加州大学奥马哈大学，内布拉斯加州林肯大学， 内布拉斯加州大学科尔尼大学，其他机构合作，其他教师 与我们联系或已被孢子科学委员会确定的机构，内部 顾问委员会或外部咨询委员会作为现有项目或开发人员的潜在合作者 重要的新孢子项目与胰腺癌有关。将征求两种类型的应用程序。 单个调查人员的申请针对每年高达87,500美元或更大的预算的重点项目的申请 协作翻译项目涉及两个或更多的调查人员，预算最高为$ 175,000 年。申请由由内部顾问委员会组成的研究部分审查 没有冲突的孢子计划，来自UNMC Eppley癌症的科学家和临床医生 中心。最终选择资助的申请是由外部顾问委员会做出的，他充当 咨询委员会在与Brattain博士和Grem博士协商时，他们是行政领导人 发展研究计划。资助的项目必须具有一组可量化的里程碑 成就代表了第一年结束时可接受的进度。