CORE--GENERAL LABORATORY SUPPORT FACILITIES

核心——一般实验室支持设施

• 批准号: 7634547
• 负责人: LUKA MILAS
• 金额: $ 29.18万
• 依托单位: UNIVERSITY OF TX MD ANDERSON CAN CTR
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7634547
• 关键词: Breeding; Companions; Custom; Data; Histology; Human; Immunohistochemistry; Laboratories; Logistics; Mus; Production; Protocols documentation; Radiation; Radiation Oncology; Research; Virus; design; dosimetry; germ free condition; in vivo; irradiation; laboratory facility; research study; tumor xenograft

The General Laboratory facility Core will breed and maintain all Ncr nu/nu mice in the Department of Experimental Radiation Oncology specific pathogen free (virus negative) mouse colony for all in vivo experiments. This core will also provide for the production of routine histology/immunohistochemistry of human tumor xenografts. Lastly, it will provide for the design and manufacture of custom jigs for irradiation of mice and perform dosimetry for all proposed radiation experiments.

通用实验室设施核心将为所有体内实验的实验辐射肿瘤学特定病原体（病毒阴性）小鼠菌落繁殖并维持所有NCR NU/NU小鼠。该核心还将提供人类肿瘤异种移植物的常规组织学/免疫组织化学的产生。最后，它将提供定制夹具的设计和制造，以辐射小鼠，并为所有提出的辐射实验进行剂量测定法。