Continuation of Follow-up of DES-exposed Cohorts

继续对 DES 暴露组进行随访

• 批准号: 7584750
• 金额: $ 26.32万
• 依托单位国家: 美国
• 财政年份: 2005
• 资助国家: 美国
• 起止时间: 2005-09-30 至 2010-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7584750
• 关键词: Continuation; Follow; up; DES; exposed

Our overall objectives are to 1) follow-up the second and third generation cohorts at Dartmouth, 2) lead the five-center third generation study, and 3) lead and contribute to manuscript development. Follow-up activities include tracing cohort members, sending questionnaires, conducting telephone interviews, obtaining written consent for medical record access, retrieving medical records, and submitting data to the coordinating center. We will also lead the third generation study. Broadly, this responsibility includes maintaining the third generation cohort registry, overseeing data collection, and documenting operational decisions. We will develop third generation study-related materials, including the study protocol, questionnaire, pathology abstraction forms, and transmittal forms. Incoming data will be entered into electronic files, double-entered, and verified. Questionnaires and non response forms will be reconciled with other data sources, including the cohort registry and the study centers' progress reports. The computerized data will be edited and cleaned, and analyses files will be created and distributed to other centers. We also propose to continue our role in manuscript development. Currently, the Dartmouth study center leads three papers, covering three generations of the cohorts, and additional papers will be undertaken when the follow-up data are mature. We will also continue to contribute to manuscripts initiated at the other study centers.

我们的整体目标是1）在达特茅斯的第二代和第三代队列的跟进，2）领导五分之一的第三代研究，3）领导并为手稿开发做出了贡献。后续活动包括追踪队列成员，发送问卷调查，进行电话访谈，获得病历访问的书面同意，检索医疗记录以及将数据提交给协调中心。我们还将领导第三代研究。从广义上讲，这项责任包括维护第三代队列注册表，监督数据收集以及记录操作决策。我们将开发与研究相关的第三代材料，包括研究方案，问卷，病理抽象形式和透射形式。传入的数据将输入到电子文件中，并进行双输入并进行了验证。问卷和非响应表将与其他数据源进行调查，包括同类登记册和研究中心的进度报告。计算机数据将进行编辑和清洁，并将创建分析文件并分配给其他中心。我们还建议继续我们在手稿开发中的作用。目前，达特茅斯研究中心（Dartmouth Study Center）领导了三篇论文，涵盖了三代人群，并且在随访数据成熟时将进行其他论文。我们还将继续为在其他研究中心发起的手稿做出贡献。