GENETICS OF CARDIAC DISEASE

心脏病遗传学

• 批准号: 7604797
• 负责人: Elizabeth M McNally
• 金额: $ 0.11万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7604797
• 关键词: Arrhythmia; Cardiology; Cardiomyopathies; Cardiovascular Diseases; Clinic; Computer Retrieval of Information on Scientific Projects Database; DNA; Dilated Cardiomyopathy; Family; Family history of; Family member; Funding; Genetic; Grant; Heart Diseases; Inherited; Institution; Mutation; Recruitment Activity; Research; Research Personnel; Resources; Sampling; Source; Study Subject; United States National Institutes of Health; base

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Subjects with dilated cardiomyopathy and arrhythmias have been recruited to identify the genetic basis for these cardiovascular disorders. Subjects are identified from the Cardiology clinics as well as by referral. Medical and family histories are obtained from study subjects. When possible, family members may be recruited into the study. We have ascertained several large families with inherited forms of cardiomyopathy and arrhythmia. DNA samples from these subjects are being studied for mutations.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 患有扩张型心肌病和心律失常的受试者已被招募来确定这些心血管疾病的遗传基础。受试者是通过心脏病诊所以及转诊来确定的。病史和家族史来自研究对象。如果可能，可以招募家庭成员参与研究。我们已经确定了几个患有遗传性心肌病和心律失常的大家族。正在研究这些受试者的 DNA 样本是否存在突变。