Graded Structures for Damage Resistant All-Ceramic Restorations

用于抗损伤全瓷修复体的分级结构

• 批准号: 7676205
• 负责人: Yu Zhang
• 金额: $ 38.08万
• 依托单位: NEW YORK UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-09-01 至 2011-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7676205
• 关键词: Accounting; Aluminum Oxide; Behavior; Biomedical Engineering; Cementation; Ceramics; Cereals; Classification; Clinical; Dental; Dental Porcelain; Dental Prosthesis; Dental crowns; Diet; Eating; Engineering; Environment; Equilibrium; Esthetics; Exhibits; Failure; Fatigue; Figs - dietary; Finite Element Analysis; Fracture; Generations; Glass; Goals; Growth; Health; Heating; Industry; Infiltration; Investigation; Knowledge; Life; Life Style; Literature; Macor; Maps; Morbidity - disease rate; Optics; Orthopedics; Patients; Permeability; Play; Porosity; Property; Prosthesis; Public Health; Radial; Relative (related person); Reporting; Research; Research Personnel; Residual state; Resistance; Role; Science; Silicon Dioxide; Slide; Social Functioning; Staging; Steel; Stress; Structure; Surface; System; Technology; Temperature; Thick; Tooth structure; Water; Work; Zirconium; aluminosilicate; base; biomaterial compatibility; ceramic restoration; cost; design; improved; interest; layered ceramics; loss of function; next generation; premature; programs; response; restorative dentistry; silicon nitride; theories; tungsten carbide (WC); yttria; zirconium oxide

DESCRIPTION (provided by applicant): Ceramics are widely used in dental and orthopedic prostheses because of their aesthetics, inertness, and biocompatibility. However, ceramics are vulnerable to fracture which accounts for millions of dollars annually in replacement costs and can cause significant patient discomfort and loss of productive lifestyle. Our preliminary investigations have established relations between failure modes and crown thickness, surface conditions, properties of the ceramic, and loading conditions. These findings indicate that monolithic glass- ceramic crowns and veneered alumina crowns are vulnerable to both near-contact occlusal damages and cementation internal surfaces radial fractures, while the veneered Y-TZP crowns are prone to veneer fracture owing to the superior strength of zirconia frameworks. These findings are consistent with clinical reports. It is the fracture problem of ceramic prostheses that motivated us to develop a new generation of damage resistant ceramic prostheses utilizing functionally graded materials. Recent theoretical and experimental advances demonstrate unprecedented resistance to contact damage in functionally graded materials that otherwise cannot be realized in conventional homogeneous materials. Our long-term goal is to develop an aesthetic, strong, thin zirconia based functionally graded material for less invasive all-ceramic posterior crowns and bridges, foreshadowing possibilities for orthopedic and other engineering applications. The objective of this proposal is to fabricate and validate the contact and flexural damage resistances of ceramic layer structures with continuous gradation from both top and bottom surfaces. We propose to achieve this objective through two specific aims: 1. Develop and characterize a new glass/zirconia/glass composite with continuous elastic modulus gradation from outer surfaces (low modulus glass-ceramic) to interior (strong, dense, fine-grain zirconia); and 2. Optimize the function-property (aesthetics, damage resistance-microstructure) relation of glass/zirconia/glass subjected to cyclic loading in water. Our preliminary studies have demonstrated that a functionally graded glass/zirconia/glass sandwich structure with improved damage resistance and aesthetics compared to their bulk zirconia counterparts can be produced by infiltrating a low elastic modulus glass-ceramic into the surfaces of a presintered zirconia. Relevance to public health: Knowledge generated from this investigation will guide design of a new generation of functionally graded ceramic dental and orthopedic prostheses with improved lifetime by resistance to contact damage and flexural fatigue, reducing morbidity and costs of replacement to the public.

描述（由申请人提供）：陶瓷由于其美学，惰性和生物相容性而被广泛用于牙科和骨科假体中。但是，陶瓷很容易受到骨折的攻击，该破裂每年占数百万美元的替代成本，并可能导致严重的患者不适和生产生活方式的丧失。我们的初步研究已经建立了故障模式与冠状厚度，表面条件，陶瓷的特性和负载条件之间的关系。这些发现表明，整体玻璃陶瓷冠和贴面氧化铝冠很容易受到近触觉咬合损伤和胶结内部表面径向骨折的影响，而贴面的Y-TZP冠状则容易受到齐罗尼亚框架的优势强度，因此容易出现贴面裂缝。这些发现与临床报告一致。陶瓷假体的断裂问题促使我们利用功能分级的材料开发了新一代的抗损伤陶瓷假体。最新的理论和实验进步表明，在功能分级材料中对接触损害的抗药性是在常规均匀材料中无法实现的。我们的长期目标是开发一种审美，坚固，薄的基于氧化锆的功能分级材料，以减少侵入性的全陶瓷后冠和桥梁，骨科和其他工程应用的预示可能性。该提案的目的是制造和验证陶瓷层结构的接触和弯曲损伤阻力，并从顶部和底部均连续渐变。我们建议通过两个具体目标来实现这一目标：1。开发和表征新的玻璃/锆/玻璃复合材料，并从外表面（低模量玻璃陶瓷）到内部（强，密集，细，细粒氧化锆）具有连续的弹性模量渐变；和2。优化玻璃/氧化锆/玻璃在水中经受环状载荷的玻璃/氧化橄榄球/玻璃的关系（美学，抗抗性 - 微观结构）。我们的初步研究表明，与其散装氧化锆相比，具有改善损伤性和美学的功能分级玻璃/锆/玻璃三明治结构可以通过将低弹性模量玻璃陶瓷浸入到预定Zirconia的表面中来产生。与公共卫生的相关性：这项调查产生的知识将指导新一代具有功能分级的陶瓷牙科和骨科假体的设计，并通过抵抗接触损害和弯曲疲劳，降低发病率和更换公众的成本，从而改善了寿命。