Mentoring Young Minds to Increase Diversity in the Biomedical Research

指导年轻人增加生物医学研究的多样性

基本信息

批准号：
10356136
负责人：
Antonio De Maio
金额：
$ 55.17万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-03-01 至 2024-01-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10356136
关键词：
Address Admission activity Biomedical Research California Communities Complement Data Analyses Data Collection Desire for food Development Doctor of Philosophy Economically Deprived Population Economics Education Enrollment Ethics Ethnic group Experimental Designs Exposure to Faculty Funding Graduate Education Group Meetings Individual Instruction Journals Knowledge Laboratories Laboratory Research Learning Life Measurable Mentors Mentorship Methodology Mind Motivation Participant Peer Review Phase Postdoctoral Fellow Preparation Process Program Development Publications Reading Records Research Research Activity Research Personnel Research Project Grants Safety Schools Science Seasons Students Supervision Teacher Professional Development Techniques Training Underrepresented Populations Universities Work career college disabled students disadvantaged background disadvantaged student education research experience experimental study faculty mentor graduate student interest laboratory experience laboratory experiment lectures meetings member programs role model satisfaction skills social social disadvantage socioeconomics student mentoring student training success undergraduate student university student

项目摘要

PROJECT SUMMARY A diverse educational and scientific community is a vital component for developing a robust work force that can address the technological and social challenges of the U.S. in a new global economy. However, the access of students from disadvantaged social and economic backgrounds to graduate education (Ph.D. level) is still low in comparison with individuals from more privileged socioeconomic groups. This disparity is amplified during academic life, resulting in a lack of faculty diversity at most U.S. universities. To address this problem, the Initiative for Maximizing Student Development (IMSD) program was established in 2008 at the University of California San Diego (UCSD), which focuses on motivating, mentoring, and facilitating the transition of students from disadvantaged economic and social backgrounds and students with disabilities from college to graduate school. The UCSD-IMSD program is composed of two consecutive phases directed at mentoring students from their initial college education to enrolling into a Ph.D. program in biomedical sciences. Phase 1 is directed at introducing freshmen students with no or limited prior research experience to scientific work via fundamental experimental instruction within the Basic Methodology Training Laboratory (BMTL). In this setting, students learn the essential research principles and skills (laboratory safety, basic techniques, data collection, and analysis) that will prepare them to participate in organized research projects. During Phase 2, students participate in hands-on, bench research projects under the mentorship of established, well-funded investigators, where they develop an appetite for science. Students are trained in several aspects of science, including experimental design, execution, data analysis and presentations, increasing their competitiveness as graduate school candidates. In addition, students are motivated to enroll into Ph.D. programs and are assisted during the process.

项目概要多元化的教育和科学界是培养强大劳动力的重要组成部分，解决美国在新的全球经济中面临的技术和社会挑战。然而，访问来自社会和经济背景较差的学生接受研究生教育（博士水平）的比例仍然较低与来自更有特权的社会经济群体的个人相比。这种差距在期间被放大学术生活，导致大多数美国大学缺乏教师多样性。为了解决这个问题，最大化学生发展计划 (IMSD) 项目于 2008 年在University of 加州圣地亚哥 (UCSD)，专注于激励、指导和促进过渡来自经济和社会背景不利的学生以及从大学到大学的残疾学生研究所。 UCSD-IMSD 项目由两个连续的阶段组成，旨在指导学生从最初的大学教育到攻读博士学位。生物医学科学计划。第一阶段旨在向没有或没有有限研究经验的新生介绍科学知识通过基本方法培训实验室内的基本实验指导进行工作（BMTL）。在这种环境下，学生学习基本的研究原理和技能（实验室安全、基本研究原理和技能）技术、数据收集和分析），这将使他们为参与有组织的研究项目做好准备。在第二阶段，学生在导师的指导下参与实践、实验研究项目资金雄厚的知名研究人员，他们对科学产生了兴趣。学生接受培训科学的几个方面，包括实验设计、执行、数据分析和演示，提高他们作为研究生院候选人的竞争力。此外，学生报名的积极性也很高攻读博士学位计划并在此过程中得到协助。

项目成果

期刊论文数量（29）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

ZNF423 patient variants, truncations, and in-frame deletions in mice define an allele-dependent range of midline brain abnormalities.

小鼠中的 ZNF423 患者变异、截短和框内缺失定义了等位基因依赖性中线脑异常范围。

DOI：
发表时间：
2020-09
期刊：
影响因子：
4.5
作者：
Deshpande, Ojas;Lara, Raquel Z;Zhang, Oliver R;Concepcion, Dorothy;Hamilton, Bruce A
通讯作者：
Hamilton, Bruce A

Bacterial Hsp70 (DnaK) and mammalian Hsp70 interact differently with lipid membranes.

细菌 Hsp70 (DnaK) 和哺乳动物 Hsp70 与脂质膜的相互作用不同。

DOI：
发表时间：
2016-07
期刊：
影响因子：
3.8
作者：
Lopez, Victor;Cauvi, David M;Arispe, Nelson;De Maio, Antonio
通讯作者：
De Maio, Antonio

Leptospiral pathogenomics.

钩端螺旋体病原学。

DOI：
发表时间：
2014-04-10
期刊：
影响因子：
0
作者：
Lehmann, Jason S;Matthias, Michael A;Vinetz, Joseph M;Fouts, Derrick E
通讯作者：
Fouts, Derrick E

The RNA-Binding Protein ELAVL1 Regulates GnRH Receptor Expression and the Response to GnRH.

RNA 结合蛋白 ELAVL1 调节 GnRH 受体表达和对 GnRH 的反应。

DOI：
发表时间：
2019
期刊：
影响因子：
4.8
作者：
Terasaka, Tomohiro;Kim, Taeshin;Dave, Hiral;Gangapurkar, Bhakti;Nicholas, Dequina A;Muñoz, Oscar;Terasaka, Eri;Li, Danmei;Lawson, Mark A
通讯作者：
Lawson, Mark A

Tumor necrosis factor expression is ameliorated after exposure to an acidic environment.

暴露于酸性环境后肿瘤坏死因子表达得到改善。

DOI：
10.1016/j.jss.2010.08.005
发表时间：
2012-03
期刊：
The Journal of surgical research
影响因子：
0
作者：
Grabowski J;Vazquez DE;Costantini T;Cauvi DM;Charles W;Bickler S;Talamini MA;Vega VL;Coimbra R;De Maio A
通讯作者：
De Maio A