EPITHELIAL ELECTROPHYSIOLOGY CORE

上皮电生理核心

• 批准号: 7610455
• 负责人: DANIEL C MARCUS
• 金额: $ 2.08万
• 依托单位: KANSAS STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-07-01 至 2008-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7610455
• 关键词: Centers of Research Excellence; Computer Retrieval of Information on Scientific Projects Database; Core Facility; Culicidae; Duct (organ) structure; Electrophysiology (science); Epithelial; Epithelium; Equus caballus; Funding; Grant; Hindgut; Institution; Intestines; Ion Transport; Ions; Kidney; Measurement; Membrane Potentials; Mentors; Non-Steroidal Anti-Inflammatory Agents; Polyamines; Regulation; Research; Research Personnel; Resources; Source; Training; United States National Institutes of Health; Vas deferens structure; instrumentation; intestinal epithelium; migration; peptide hormone

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Core D supports the COBRE Epithelial Electrophysiology Core facility. The Core provides the instrumentation, expertise, training and mentoring in epithelial electrophysiology necessary to advance COBRE projects on different epithelia, including: "Transepithelial Ion Transport and Its Regulation" (renal collecting ducts and vas deferens), "Intestinal Epithelial Migration: NSAID, Polyamine-depletion, and Depolarized Membrane Potential" (equine intestinal epithelia) and Transepithelial Ion Transport in Mosquito Hindgut Controlled by Peptide Hormone. These projects are critically dependent on making noninvasive current and nonradioactive ion flux measurements.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目和 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 中心，不一定是研究者的机构。 Core D 支持 COBRE 上皮电生理学核心设施。核心提供上皮电生理学方面必要的仪器、专业知识、培训和指导，以推进针对不同上皮的 COBRE 项目，包括：“跨上皮离子转运及其调节”（肾集合管和输精管）、“肠上皮迁移：NSAID、多胺” -消耗和去极化膜电位”（马肠上皮）和蚊子后肠中的跨上皮离子转运由肽激素控制。这些项目主要依赖于无创电流和非放射性离子通量测量。