MULTI-ECHO WATER-FAT SEPARATION

多回波水脂分离

• 批准号: 7601920
• 负责人: WENXIAO LU
• 金额: $ 1.73万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-06-01 至 2008-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7601920
• 关键词: Address; Chemicals; Computer Retrieval of Information on Scientific Projects Database; Fatty acid glycerol esters; Funding; Grant; Image; Imaging Techniques; Institution; Maps; Methods; Morphologic artifacts; Motion; Purpose; Research; Research Personnel; Resolution; Resources; Scanning; Source; Standards of Weights and Measures; Techniques; United States National Institutes of Health; Water; Work; improved; novel; time use

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Purpose: This project aims to enable fast and efficient scanning with robust water-fat separation using multi-echo sequences. To achieve this aim, requires a combination of robust field-map estimation and imaging techniques that work with novel multi-echo sequences. Methods: We have developed a multi-resolution field map estimation method that directly locates possible field map values at a coarse resolution and then progressively refines field map estimation to full resolution. To improve imaging efficiency and reduce motion induced artifacts, we have implemented a bipolar multi-echo sequence that acquires images at different echo times using alternating readout gradients to maximize scan efficiency. For practical use, the problems caused by the alternating readout gradients, including k-space echo misalignment, field-inhomogeneity induced misregistration, and chemical-shift induced misregistration must be addressed. Summary: The developed techniques and sequences offer many advantages such as high SNR efficiency, reduced echo-spacing compared to standard multi-echo sequences, reduced motion induced artifacts, and reliable field-map estimation and water-fat separation.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 目的：该项目旨在使用多回波序列通过强大的水脂分离来快速有效扫描。为了实现这一目标，需要结合与新型多回波序列一起使用的鲁棒场映射估计和成像技术。 方法：我们已经开发了一种多分辨率字段映射估计方法，该方法将可能的字段映射值直接以粗分辨率定位，然后逐步将现场图估计估计到完整分辨率。为了提高成像效率并降低运动引起的伪影，我们实施了双极多回波序列 使用交替的读取梯度在不同的回声时间获取图像，以最大程度地提高扫描效率。 为了实际使用，必须解决由K-Space Echo未对准，现场接触性诱导的误导和化学班次诱导的误导率在内的交替读数梯度引起的问题。 摘要：与标准的多回波序列相比，开发的技术和序列具有许多优势，例如高SNR效率，回声间距的降低，运动诱导的伪像减少以及可靠的现场映射估计和水脂肪分离。