UTPA - Cancer Center at UTHSCSA Border Partnership (1 of 2)

UTPA - UTHSCSA 边境合作癌症中心（1 of 2）

基本信息

批准号：
7616292
负责人：
Bimal K Banik
金额：
$ 26.29万
依托单位：
UNIVERSITY OF TEXAS RIO GRANDE VALLEY
依托单位国家：
美国
项目类别：
财政年份：
2008
资助国家：
美国
起止时间：
2008-09-26 至 2012-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/7616292
关键词：
Address Affinity American Amides Amines Antineoplastic Agents Apoptosis Apoptotic Aromatic Compounds Attitude Basic Science Binding Biological Cancer Biology Cancer Burden Cancer Center Cell Death Cell Survival Chrysenes Class Clinical Trials Communities Critiques Decision Making Education Effectiveness Electrons Fostering Genetic screening method Goals Health Sciences Hispanics Human In Vitro Individual Laboratories Latino Lead Learning Malignant Neoplasms Measures Metabolism Methods Mexico Minority Mus Natural Killer Cells Normal tissue morphology Numbers Pan Genus Pathway interactions Pilot Projects Play Population Postdoctoral Fellow Preparation Process Research Research Personnel Research Training Role Side South Texas Students System T-Lymphocyte TdT-Mediated dUTP Nick End Labeling Assay Testing Texas Toxic effect Training Training Programs Translational Research Tumor Cell Line Universities Work Writing alkalinity analog anticancer research base cancer risk cancer therapy caspase-3 health disparity in vivo interest leukemia malignant breast neoplasm programs tumor

项目摘要

DESCRIPTION (provided by applicant): The Latino/Hispanic population is the largest minority in the US and the highest concentration of Latinos is along the US-Mexico Border. To address the specific needs of this population in cancer research and education, a partnership between The University of Texas-Pan American and the Cancer Center at The University of Texas Health Science Center at San Antonio is proposed. The goals of this application are to develop research and training partnerships to increase the cancer research base on the US-Mexico border. The projects proposed will not only develop translational research in basic science but also address cancer related health disparities in the Hispanic border population. The specific goals of the application are: 1. to develop and foster cancer research at UTPA; 2. to foster research dedicated towards reducing the cancer burden of the Hispanic population with emphasis on the US-Mexico border, and 3. to increase the number of cancer researchers coming from South Texas. To accomplish these goals, two pilot projects and a training program are proposed. The first pilot project is a basic science project which will take advantage of the expertise at UTPA to synthesize polycyclic aromatic compounds and expertise at UTHSCSA to test these compounds as anticancer agents. The second pilot project is directed toward understanding the attitudes and decision making processes in genetic testing for increased breast cancer risk. The third project is a summer undergraduate program for UTPA students to work in laboratories and to learn about cancer biology with the goal of increasing the number of students from communities in South Texas interested in cancer research. This multidimensional approach will heighten cancer research and education in the Hispanic/Latino population along the Texas border.

描述（由申请人提供）：拉丁裔/西班牙裔人口是美国最大的少数族裔，拉丁裔人口最集中的地区是美墨边境沿线。为了满足这一人群在癌症研究和教育方面的特殊需求，德克萨斯大学泛美分校和圣安东尼奥德克萨斯大学健康科学中心的癌症中心建立了合作伙伴关系。该应用程序的目标是发展研究和培训合作伙伴关系，以增加美墨边境的癌症研究基础。拟议的项目不仅将发展基础科学的转化研究，还将解决西班牙裔边境人口中与癌症相关的健康差异。该申请的具体目标是： 1. 发展和促进 UTPA 的癌症研究； 2. 促进致力于减少西班牙裔人口癌症负担的研究，重点是美国-墨西哥边境，以及 3. 增加来自德克萨斯州南部的癌症研究人员的数量。为了实现这些目标，提出了两个试点项目和一个培训计划。第一个试点项目是一个基础科学项目，将利用 UTPA 合成多环芳香族化合物的专业知识和 UTHSCSA 的专业知识来测试这些化合物作为抗癌剂。第二个试点项目旨在了解基因检测中乳腺癌风险增加的态度和决策过程。第三个项目是一个暑期本科项目，供 UTPA 学生在实验室工作并学习癌症生物学，目的是增加南德克萨斯社区对癌症研究感兴趣的学生数量。这种多维方法将加强德克萨斯州边境沿线西班牙裔/拉丁裔人口的癌症研究和教育。