PHASE II STUDY OF TIRAPAZAMINE (NSC-13018)/CISPLATIN/ETOPOSIDE IN LUNG CANCER

替拉扎明 (NSC-13018)/顺铂/依托泊苷治疗肺癌的 II 期研究

• 批准号: 7607167
• 负责人: Carey Wexler Sherman
• 金额: $ 0.05万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-08-01 至 2008-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607167
• 关键词: Cancer Center; Cancer Patient; Cisplatin/Etoposide/Tirapazamine; Computer Retrieval of Information on Scientific Projects Database; Enrollment; Funding; Future; Grant; Institution; Malignant neoplasm of lung; Nature; Patients; Phase II Clinical Trials; Purpose; Radiation therapy; Reporting; Research; Research Personnel; Resources; Sampling; Services; Site; Source; Specimen; Specimen Handling; Standards of Weights and Measures; Tissues; United States National Institutes of Health; cisplatin/etoposide protocol; lung small cell carcinoma; research study; tirapazamine

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The purpose of this study is to find out what the effects, good and bad, the combination of tirapazamine, cisplatin, and etoposide with radiation therapy followed the combintation of cisplatin and etoposide has on patients with small cell lung cancer. Tirapazamine is an experimental agent. The investigationsl nature of this study is the addition of tirapazamine to standard chemotherpay and radiotherapy. In addition to this treatment, the investigators will take part in establishing a lung cancer specimen bank, which will store tissues from lung cancer patient to use in current and future scientific research studies. This study is being conducted at the Hollings Cancer Center, and are asking for GCRC lab services that cannot be provided through MUSC, which is storage and sample processing for specimens requiring a refrigerated centrifuge. 04/2006 There are no reports of subject enrolled at this site for this study. Recruitment is ongoing.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 这项研究的目的是找出tirapazamine，cisplatin和epoposide与放射治疗的影响，好与坏，遵循顺铂和依托泊苷对小细胞肺癌患者的结合之后。 提拉帕舍胺是一种实验剂。 这项研究的研究性质是在标准化疗和放射疗法中添加Tirapazamine。 除这种治疗方法外，研究人员还将参与建立肺癌标本库，该库将存储来自肺癌患者的组织以在当前和未来的科学研究中使用。 这项研究是在Hollings癌症中心进行的，并要求通过MUSC提供的GCRC实验室服务，这是需要冷藏离心机的样品的存储和样品处理。 04/2006本网站上没有关于本研究的受试者的报道。 招聘正在进行。