EFFECT OF AGING ON CROSS-MODAL SENSORY PROCESSING

衰老对跨模式感觉处理的影响

• 批准号: 7607689
• 负责人: Paul Laurienti
• 金额: $ 0.49万
• 依托单位: WAKE FOREST UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-03-01 至 2008-02-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7607689
• 关键词: Adult; Affect; Age; Aging; Brain imaging; Brain region; Communication; Computer Retrieval of Information on Scientific Projects Database; Elderly; Exhibits; Funding; Grant; Human; Individual; Institution; Knowledge; Life; Life Expectancy; Longevity; Medical; Memory impairment; Modality; Population; Process; Quality of life; Research; Research Personnel; Resources; Science; Sensory; Sensory Process; Source; United States National Institutes of Health; Woman; age effect; age related; behavior test; body system; disability; experience; falls; man; normal aging; sensory system

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Advances in medical science have enabled us to continually increase life expectancy. In just over the past 40 years, the life expectancy of a woman has risen from 70 to nearly 80 years, and the life expectancy of a man has risen farom 65 to over 70 years. Thus, the population is continually aging, and although we have increased the expected life span such that individuals can expect to live more than 70 years, quality of life is an important factor that is often not considered. As humans age, they experience problems associated with both excessive use and disuse of organ systems. In fact, it has been shown that all sensory systems exhibit diminished function with age. Recent studies have also suggested that the integration of information from multiple sensory modalities (cross-modal processing) is affected by normal aging. Interestingly, many of the disabilities associated with aging that may impact the quality of life, such as increased falls, communication disturbances, and memory impairment, may be associated with an alteration of cross-modal processing. Yet, no specific study has been dedicated to evaluating age-related changes in brain regions that integrate sensory information. The studies proposed here will fill this knowledge gap by studying both unimodal and cross-modal processes in young and elderly adults using functional brain imaging and behavioral testing.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 医学的进步使我们能够不断提高预期寿命。 在过去的40年中，女性的预期寿命已从70年增加到近80年，男人的预期寿命已增加了65年的Farom 65岁到70多年。 因此，人口正在不断衰老，尽管我们已经增加了预期的寿命，使个人可以期望生活超过70年，但生活质量是通常不考虑的重要因素。 随着人类的年龄，他们会遇到与过度使用和破坏器官系统有关的问题。 实际上，已经显示所有感觉系统随着年龄的增长而表现出降低的功能。 最近的研究还表明，来自多种感觉方式（跨模式处理）的信息的整合受正常衰老的影响。 有趣的是，许多与衰老相关的残疾可能会影响生活质量，例如增加跌倒，交流障碍和记忆力障碍，可能与跨模式处理的改变有关。 然而，尚无具体研究专门用于评估整合感官信息的大脑区域中与年龄相关的变化。 此处提出的研究将通过使用功能性脑成像和行为测试的年轻和老年人中的单峰和跨模式过程来填补这一知识差距。