SEROTONIN FUNCTION IN ANOREXIA NERVOSA

血清素在神经性厌食症中的作用

• 批准号: 7606939
• 负责人: BARBARA L WOLFE
• 金额: $ 17.56万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2007
• 资助国家: 美国
• 起止时间: 2007-04-01 至 2008-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7606939
• 关键词: Anorexia Nervosa; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Neurosecretory Systems; Patients; Research; Research Personnel; Resources; Selective Serotonin Reuptake Inhibitor; Serotonin; Source; Testing; Therapeutic; United States National Institutes of Health; behavior measurement; response

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. This study examines the possible therapeutic implications of precursor augmentation to enhance serotonergic functioning in patients with Anorexia Nervosa (AN). This study tests the hypothesis that in subjects with AN short term augmentation with a serotonin precursor enhances serotonin function in comparison to an SSRI alone as measured by behavioral and neuroendocrine responses.

该子项目是利用该技术的众多研究子项目之一 资源由 NIH/NCRR 资助的中心拨款提供。子项目及 研究者 (PI) 可能已从 NIH 的另一个来源获得主要资金， 因此可以在其他 CRISP 条目中表示。列出的机构是 对于中心来说，它不一定是研究者的机构。 本研究探讨了前体增强疗法对增强神经性厌食症 (AN) 患者血清素能功能的可能治疗意义。这项研究测试了这样的假设：与单独使用 SSRI 相比，短期使用血清素前体增强 AN 的受试者可以增强血清素功能（通过行为和神经内分泌反应进行测量）。