PROTEIN REQUIREMENT IN SICKLE CELL ANEMIA

镰状细胞贫血症的蛋白质需求

• 批准号: 7605656
• 负责人: MACIEJ S BUCHOWSKI
• 金额: $ 0.67万
• 依托单位: VANDERBILT UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2006
• 资助国家: 美国
• 起止时间: 2006-12-01 至 2007-09-16
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7605656
• 关键词: Adolescent; Computer Retrieval of Information on Scientific Projects Database; Funding; Grant; Institution; Leucine; Proteins; Research; Research Personnel; Resources; Sickle Cell Anemia; Source; United States National Institutes of Health; oxidation; protein degradation

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. The central hypothesis is that increased whole-body protein turnover causes increased requirements for protein in adolescents with SCA. The specific aim is to determine how much protein is needed in growing SCA adolescents using breakpoint analysis of variables derived from leucine oxidation and whole-body protein turnover.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 中心假设是，增加的全身蛋白质更新会导致SCA青少年对蛋白质的需求增加。具体的目的是使用亮氨酸氧化和全身蛋白质更换的变量的断点分析来确定种植SCA青少年需要多少蛋白质。