Improving Minority Health in Rheumatic Diseases

改善少数民族风湿病健康

• 批准号: 9902868
• 负责人: Gary S Gilkeson
• 金额: $ 55.05万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-09-25 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9902868
• 关键词: Address; Adherence; Administrative Supplement; Advocate; Affect; African American; Alabama; Appointment; Autoimmune Diseases; Awareness; Benchmarking; Caucasians; Chronic Disease; Clinical Research; Collaborations; Color; Communities; Diagnostic; Disease; Economics; Education; Education and Outreach; Emergency department visit; Ethnic Origin; Faculty; Female; Fostering; Funding; Future; Genetic; Genetic Diseases; Grant; Grant Review; HIV; Health Services Accessibility; Hearing; Historically Black Colleges and Universities; Hospitalization; Infrastructure; Institution; International; Intervention; Kidney Diseases; Lupus; Medical; Medical center; Mentors; Mentorship; Methodology; Methods; Morbidity - disease rate; Mutation; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Outcome; Pathogenesis; Patients; Pharmaceutical Preparations; Physicians; Pilot Projects; Population; Prevalence; Program Development; Regimen; Research; Research Infrastructure; Research Methodology; Research Personnel; Research Project Grants; Research Support; Resources; Rheumatism; Risk Factors; Sampling; Scleroderma; Series; Services; Site; South Carolina; Systemic Lupus Erythematosus; Techniques; Technology; Teleconferences; Translating; Travel; Universities; Woman; Work; Writing; base; career; career development; child bearing; disparities in morbidity; early screening; ethnic disparity; health disparity; high risk; high risk population; improved; inter-institutional; medication compliance; medication nonadherence; member; minority health; mortality; novel; novel strategies; programs; ranpirnase; response; success; young woman

ABSTRACT Systemic Lupus Erythematosus is a significant chronic disease with morbidity and mortality in primarily young women of color. Our current P30 CCCR grant “Improving Minority Health in Rheumatic Diseases” is composed of three cores, administrative, methodology and patient resource. These cores provide the infrastructure for studies directed at understanding the pathogenesis of lupus and scleroderma as a method to achieve better diagnostics and treatments for these diseases. In this Administrative Supplement to the P30 we are proposing two specific projects focused on decreasing ethnic disparities in lupus to be performed at MUSC and the University of Alabama at Birmingham. The first project is to provide awareness, education and early screening in young African American females through programs and efforts at Historically Black Colleges and Universities in South Carolina and Alabama. The second project is to utilize a patient advocate for high risk African American female lupus patients based on missed appointments, medication non adherence and ER visits at both institutions. The advocate will work with the patients to improve these parameters believing that such navigation in lupus will be as successful as similar efforts in HIV. We also propose an enhancement effort consisting of a pilot project each year for both institutions, a mentoring program for junior investigators in health disparities and cross institutional sharing of expertise. The CCCR program does not include projects, but only cores. We propose to utilize this supplement mechanism to pursue projects we believe will have direct impact on ethnic disparities in lupus.

抽象的 系统性红斑狼疮是一种重要的慢性疾病，其发病率和死亡率在 我们目前的 P30 CCCR 拨款“改善少数族裔的健康”。 风湿病”由三个核心组成：管理、方法和患者资源。 这些核心为旨在了解狼疮发病机制的研究提供了基础设施 和硬皮病作为更好地诊断和治疗这些疾病的方法。 在 P30 的行政补充文件中，我们提出了两个重点关注的具体项目 减少狼疮的种族差异将在 MUSC 和阿拉巴马大学进行 伯明翰的第一个项目是为年轻人提供意识、教育和早期筛查。 非裔美国女性通过历史黑人学院的项目和努力 南卡罗来纳州和阿拉巴马州的大学第二个项目是利用患者倡导者。 基于错过预约、非药物治疗的高风险非裔美国女性狼疮患者 倡导者将与患者合作改善两家机构的依从性和急诊就诊。 这些参数相信，狼疮中的这种导航将与狼疮中的类似努力一样成功。 我们还建议开展一项加强工作，其中包括每年针对这两种疾病开展一个试点项目。 机构，针对健康差异和跨机构的初级研究人员的指导计划 CCCR 计划不包括项目，而仅包括核心知识。 这个补充机制旨在开展我们认为将对少数民族产生直接影响的项目 狼疮的差异。