Improving Mind/Body Health and Functioning with Integrative Exercise

通过综合运动改善身心健康和功能

• 批准号: 10775686
• 负责人: Thomas C Neylan
• 金额: --
• 依托单位: VETERANS AFFAIRS MED CTR SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-10-01 至 2023-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10775686
• 关键词: Aerobic Exercise; Afghanistan; Anxiety; Awareness; Breathing; Cardiovascular Diseases; Caring; Chronic Post Traumatic Stress Disorder; Cognition; Control Groups; Department of Defense; Diagnosis; Enrollment; Exercise; Exercise Therapy; Frequencies; Funding; Goals; Health; Health Services Accessibility; Health education; Hippocampus; Hour; Human Resources; Intervention; Iraq; Marines; Measures; Mediating; Medical center; Mental Depression; Mental Health; Mental Health Services; Mental disorders; Moods; Neurons; Outcome; Participant; Perception; Pilot Projects; Post-Traumatic Stress Disorders; Quality of life; Randomized; Recovery; Rehabilitation therapy; Reporting; Research Personnel; San Francisco; Sleeplessness; Soldier; Symptoms; Techniques; Testing; Training; Treadmill Tests; Treatment Protocols; United States Department of Veterans Affairs; Vasodilation; Veterans; Waiting Lists; World Health Organization; brachial artery; brief screening; cardiovascular fitness; cardiovascular health; combat veteran; efficacy study; evidence base; exercise capacity; exercise intervention; health care delivery; improved; innovation; mind/body; mindfulness; neurogenesis; new growth; physical conditioning; psychologic; rehabilitation strategy; response; seal; sleep quality; social stigma; strength training; treadmill; treatment effect

Despite the considerable efforts of the VA to improve awareness of mental health problems and access to care, many returning veterans still report substantial barriers to seeking traditional mental health care. There is a large body of evidence demonstrating that aerobic exercise effectively improves many outcomes relevant to Posttraumatic Stress Disorder (PTSD) including; anxiety, depression, insomnia, cognition, and cardiovascular disease. In addition, there is a rapidly growing evidence base showing that aerobic exercise produces an increase in the growth of new neurons (e.g., neurogenesis) and increases the volume of the hippocampus which underscores the potential value of exercise for producing broad benefits to psychological health. Recognizing the promise that exercise might hold for attracting more veterans into care and improving overall health in veterans with PTSD, a team of investigators at the San Francisco Veterans Administration Medical Center (SFVAMC) with funding from the Department of Defense developed a treatment protocol and completed a pilot study of Integrative Exercise (Aerobic exercise and Breath Training 3 weekly sessions over 12 weeks) versus a waitlist control condition. Promising results from this trial have led us to the next step which is to conduct a definitive efficacy study of Integrative Exercise versus an active health education control condition: Illness Management and Recovery (IMR). The control condition will be matched on contact hours with treatment personnel. The goal of this revised proposal is to test if Integrative Exercise improves overall quality of life, PTSD symptoms, sleep quality, and measures of cardiovascular health in combat Veterans with chronic PTSD relative to the IMR condition. Another goal is to test if improvements in quality of life are predicted by improvements in cardiovascular fitness as measured by exercise capacity on treadmill testing. Finally, the proposal will test if Integrative Exercise versus IMR will produce greater improvements in additional health outcomes, including mood, subjective sleep quality, and PTSD symptoms.

尽管弗吉尼亚州为提高心理健康问题的认识和进入 护理，许多返回的退伍军人仍然报告寻求传统精神卫生保健的重大障碍。有 大量证据表明有氧运动有效地改善了与 创伤后应激障碍（PTSD），包括；焦虑，抑郁，失眠，认知和心血管 疾病。此外，还有一个迅速增长的证据基础，表明有氧运动会产生 增加新神经元的生长（例如神经发生）并增加海马体积 这突显了锻炼对为心理健康带来广泛利益的潜在价值。 认识到锻炼可能会有可能吸引更多退伍军人照顾和改善整体的承诺 旧金山退伍军人管理局的调查员团队与PTSD的退伍军人健康 中心（SFVAMC）在国防部的资金中开发了一项治疗方案， 完成了一项综合锻炼的试点研究（有氧运动和呼气训练3每周一次会议 12周）与候补名单控制条件相比。这项试验的有希望的结果使我们达到了下一步 是对综合运动与积极的健康教育控制进行确定的功效研究 条件：疾病管理和康复（IMR）。控制条件将在接触时间匹配 与治疗人员。该修订的建议的目的是测试综合练习是否整体改善 战斗退伍军人的生活质量，PTSD症状，睡眠质量和心血管健康的度量 慢性PTSD相对于IMR条件。另一个目标是测试生活质量的改善是 通过在跑步机测试中的运动能力来衡量的心血管健康的改善预测。 最后，该提案将测试综合练习与IMR是否会在其他方面产生更大的改进 健康结果，包括情绪，主观睡眠质量和PTSD症状。