Surgical Oncology Research Training Program

肿瘤外科研究培训计划

• 批准号: 10767059
• 负责人: HERBERT CHEN
• 金额: $ 51.29万
• 依托单位: UNIVERSITY OF ALABAMA AT BIRMINGHAM
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-07-16 至 2028-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10767059
• 关键词: Research Training; Surgical Oncology; Training Programs

PROJECT SUMMARY Cancer remains one of the most common causes of death in the United States, second only to cardiovascular disease. Great need exists for continued research to prevent cancer and improve outcomes. Surgeon-scientists are uniquely positioned to translate research findings associated with surgical diseases to the bedside and operating room. Despite their unique expertise and effectiveness in research, the role of the surgeon-scientist has historically been threatened for the last few decades. Surgeon-scientists are submitting fewer career development awards and have lower success rates in obtaining NIH funding. There has been only small growth in the percentage of surgeons funded by NIH in the past 10 years, but surgical oncologists represent the largest group of surgeon subspecialists receiving NIH grants. It is critical that we continue to expand this pool of investigators and develop surgeon-scientists in the field of oncology. The overall program goal of the Surgical Oncology Research Training Program at the University of Alabama at Birmingham (UAB) is to provide surgical residents who are strongly motivated toward a career in surgical oncology with a comprehensive, mentored research and training experience that prepares them for successful careers as surgeon-scientists. The program provides surgeon-scientists who intend to enter a career in academic surgery, particularly in surgical oncology, with the opportunity for basic, translational, and health services research training in a mentored, multidisciplinary, collaborative environment. The program leverages the extensive resources of the UAB Department of Surgery, UAB O’Neal Comprehensive Cancer Center (CCC), the UAB Heersink School of Medicine’s Center for Clinical and Translational Science (CCTS), the Office of Postdoctoral Education (OPE), and an abundance of health services and disparities research programs and centers. The program includes a pool of outstanding extramurally funded trainers from a variety of cancer-related disciplines. Seven trainees have completed the program; 1 has obtained a faculty position with NCI funding, and 6 are continuing their clinical training in environments that will facilitate their continued success in developing independent academic careers. An additional 4 are currently appointed. Several have obtained additional degrees to advance their scientific knowledge, and several have been successful in obtaining additional funding to support their fellowship training or further career development. While this is a new program, it has already been successful in developing its first NIH-funded surgeon-scientist. It has also attracted a diverse group of trainees, including 27% African American and 82% female. Trainees have demonstrated excellent productivity as evidenced by publications and national presentations. These early markers of success are clear indicators of the program’s future ability to produce extramurally funded surgeon-scientists in the field of surgical oncology.

项目摘要 癌症仍然是美国最常见的死亡原因之一，第二 心血管疾病。迫切需要继续研究以预防癌症和改善预后。 外科医生科学家在将与外科疾病相关的研究结果转化为独特的位置 床边和手术室。尽管在研究中具有独特的专业知识和有效性，但 在过去的几十年中，外科医生科学家历来受到威胁。外科医生科学家正在提交 在获得NIH资金方面的职业发展奖项较少，成功率较低。有 在过去的10年中，由NIH资助的外科医生的百分比只有很小的增长，但是手术肿瘤学家 代表获得NIH赠款的最大外科医生专科医生。我们继续继续 扩大研究人员的库，并在肿瘤学领域发展外科医生科学家。 大学外科肿瘤学研究培训计划的总体计划目标 伯明翰（UAB）的阿拉巴马州将为外科居民提供强烈动机的外科居民 手术肿瘤学具有全面的，修补的研究和培训经验，为他们做好准备 作为外科医生科学家的成功职业。该计划提供了打算输入的外科医生科学家 学术手术的职业，尤其是手术肿瘤学，有机会进行基本，翻译和 卫生服务研究培训当然是多学科的协作环境。该程序 利用UAB手术部，UAB O’Neal综合癌症的大量资源 中心（CCC），UAB Heersink医学院临床与转化科学中心（CCTS）， 博士后教育办公室（OPE）以及大量的卫生服务和差异研究 程序和中心。该计划包括来自各种各样的资助培训师 与癌症有关的学科。七名学员已经完成了该计划； 1已获得教师职位 NCI资金和6个正在继续在环境中进行临床培训，这将有助于他们继续 成功发展独立的学术职业。目前已任命另外4个。有几个 获得了额外的学位来提高他们的科学知识，其中有几位成功 获得额外的资金来支持他们的奖学金培训或进一步的职业发展。虽然这是一个 新计划，它已经成功地开发了其第一个由NIH资助的外科医生科学家。它有 还吸引了一群潜水员的学员，其中包括27％的非裔美国人和82％的女性。学员 出版物和国家演讲证明了出色的生产力。 这些成功的早期标记是该计划未来生产能力的明确指标 外科肿瘤学领域的外科医生科学家。

项目成果

EZH2 inhibition decreases neuroblastoma proliferation and in vivo tumor growth.

• DOI: 10.1371/journal.pone.0246244
• 发表时间: 2021
• 期刊: PloS one
• 影响因子: 3.7
• 作者: Bownes LV;Williams AP;Marayati R;Stafman LL;Markert H;Quinn CH;Wadhwani N;Aye JM;Stewart JE;Yoon KJ;Mroczek-Musulman E;Beierle EA
• 通讯作者: Beierle EA

Participant perspectives on a department of surgery faculty mentoring program.

参与者对外科教员指导计划的看法。

• DOI: 10.1016/j.amjsurg.2022.10.060
• 发表时间: 2023
• 期刊: American journal of surgery
• 影响因子: 3
• 作者: Gillis,Andrea;Zmijewski,Polina;Corey,Britney;Fazendin,Jessica;Chen,Herbert;Lindeman,Brenessa;Hendershot,Kimberly;Dream,Sophie
• 通讯作者: Dream,Sophie

The association of social vulnerability with colorectal enhanced recovery program failure.

社会脆弱性与结直肠加速康复计划失败的关联。

• DOI: 10.1016/j.sopen.2023.03.007
• 发表时间: 2023
• 期刊: Surgery open science
• 影响因子: 1.4
• 作者: Smith,BurkelyP;Hollis,RobertH;Shao,ConnieC;Gleason,Lauren;Wood,Lauren;McLeod,MarshallC;Kay,DanielleI;Oates,GabrielaR;Pisu,Maria;Chu,DanielI
• 通讯作者: Chu,DanielI

There's no such thing as a free lunch: Outcomes of concurrent parathyroidectomy and thyroidectomy among CESQIP surgeons.

• DOI: 10.1016/j.amjsurg.2022.05.025
• 发表时间: 2022-11
• 期刊: AMERICAN JOURNAL OF SURGERY
• 影响因子: 3
• 作者: Gillis, Andrea;Chen, Herbert
• 通讯作者: Chen, Herbert

Multidisciplinary clinics for colorectal cancer may not provide more efficient coordination of care.

• DOI: 10.1016/j.amjsurg.2021.11.027
• 发表时间: 2022-06
• 期刊: AMERICAN JOURNAL OF SURGERY
• 影响因子: 3
• 作者: Bajpai, Swara;Wood, Lauren;Cannon, Jamie A.;Chu, Daniel I.;Hollis, Robert H.;Gunnells, Drew J.;Hardiman, Karin M.;Kennedy, Gregory D.;Morris, Melanie S.
• 通讯作者: Morris, Melanie S.