Leveraging mHealth to Increase Health Equity among Black Individuals with Opioid Use Disorder and Commonly Occurring Mental Health Disorders

利用移动医疗提高患有阿片类药物使用障碍和常见心理健康障碍的黑人的健康公平

• 批准号: 10722105
• 负责人: Hannah Szlyk
• 金额: $ 18.05万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2023
• 资助国家: 美国
• 起止时间: 2023-08-15 至 2028-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10722105
• 关键词: Achievement; Address; Adherence; Anxiety; Applied Skills; Area; Attitude; Award; Black American; Black Populations; Black race; Caring; Cessation of life; Cities; Client; Clinical; Clinical Trials; Control Groups; Data; Development; Discrimination; Economics; Elements; Environment; Evidence based treatment; Exposure to; Face; Feedback; Focus Groups; Fostering; Foundations; Future; Goals; Health education; Healthcare; Inequity; Intervention; Interview; Life; Location; Mental Depression; Mental Health; Mental disorders; Mentored Research Scientist Development Award; Mentors; Mentorship; Methodology; Methods; Minority Groups; Missouri; Opioid; Outcome; Overdose; Participant; Persons; Pharmaceutical Preparations; Population; Prevention strategy; Provider; Public Health; Race; Randomized; Randomized, Controlled Trials; Recovery; Recovery Support; Reporting; Research; Research Activity; Research Methodology; Research Personnel; Research Project Grants; Resources; Risk Factors; Scientist; Structural Racism; Structure; Telephone; Testing; Text Messaging; Therapeutic Intervention; Training; Training Activity; United States; United States Dept. of Health and Human Services; United States National Institutes of Health; United States Substance Abuse and Mental Health Services Administration; Universities; Washington; acronyms; addiction; barrier to care; career; career development; clinical care; community based care; cost effective intervention; depressive symptoms; design; digital; digital treatment; experience; health care availability; health equity; health equity promotion; high risk; implementation facilitators; implementation science; implementation strategy; improved; innovation; mHealth; medical schools; medication for opioid use disorder; meetings; metropolitan; mortality; motivational enhancement therapy; opioid epidemic; opioid mortality; opioid overdose; opioid policy; opioid use disorder; overdose prevention; overdose risk; peer; peer support; prevent; primary outcome; psychoeducation; psychoeducational; response; secondary outcome; skill acquisition; skills; sobriety; social factors; social stigma; structural determinants; substance use; substance use treatment; success; symposium; tool; treatment adherence; uptake; usability; user centered design

Project Summary The overarching goal of this Research Scientist Development Award (K01) is to provide Dr. Hannah Szlyk with the training and research activities needed to become an independent researcher who develops, tests, and implements cutting-edge digital therapeutic interventions that can promote health equity in recovery from opioid use disorder (OUD) plus commonly occurring mental disorders (COMD). This application outlines an integrated training and research plan that will provide Dr. Szlyk with the skills needed to achieve her career goal. Under the mentorship of experts in clinical trials, health equity, implementation science, user-centered design, and OUD research, Dr. Szlyk’s training will focus on the following key areas: (1) clinical trial methodology (Dr. Esther Lu; (2) implementation science and user-centered design (Drs. Patricia Cavazos-Rehg and Emily C. Williams); and (3) health equity in addictions and mental health (Dr. Darrell Hudson). Training in these three areas will be achieved through didactic and applied activities, participation in national conferences and institutes, and mentoring meetings. Dr. Szlyk will apply the skills acquired during the training activities to conduct a research project to appropriately adapt and test an mHealth intervention for Black Americans with OUD plus COMD. Rates of opioid-related deaths continue to rise among Black Americans in the United States. These deaths are often concentrated in medium-sized metropolitan cities, like St. Louis, Missouri, where this research is set. Yet, few interventions are developed to fit the unique needs of Black clients; none address their heightened overdose risk often compounded by COMD which decreases likelihood for recovery success. Also, Black individuals experience significant barriers to life saving OUD treatments, like medication for OUD (MOUD), because of structural racism. To address this gap, the K01 research project will integrate public health critical race praxis, implementation science, and user-centered design strategies to appropriately adapt an mHealth intervention for Black Americans with OUD plus COMD. The central hypothesis is that adaptations to the mHealth intervention will improve engagement and usability among Black participants, improve adherence to MOUD, and impact decreases in COMD. This research will address key gaps in treatment by 1) adapting an mHealth intervention for Black individuals with OUD plus COMD; 2) identifying barriers and facilitators to implementing an mHealth intervention among stakeholders who serve Blacks with OUD plus COMD; 3) examining the preliminary efficacy of an adapted mHealth intervention. These data will inform the design of a larger RCT for a future R01 application. Dr. Szlyk’s training and proposed research will be carried out in the outstanding intellectual environment of Washington University School of Medicine, which will provide her with a multitude of resources to meet her goals.

项目摘要 该研究科学家发展奖（K01）的总体目标是向汉娜·史兹利克（Hannah Szlyk）博士提供 培训和研究活动需要成为一名独立研究人员，他开发，测试和 实施尖端的数字治疗干预措施，可以促进从 Opioid使用障碍（OUD）加上常见的精神障碍（COMD）。此应用程序概述了 综合培训和研究计划将为Szlyk博士提供实现职业所需的技能 目标。在临床试验，健康公平，实施科学方面的专家的心态下，以用户为中心 设计和OUD研究，Szlyk博士的培训将重点放在以下关键领域：（1）临床试验 方法论（Esther Lu博士；（2）实施科学和以用户为中心的设计（Dr.Patricia Cavazos-Rehg 和艾米丽·C·威廉姆斯（Emily C. Williams））； （3）成瘾和心理健康中的健康公平（Darrell Hudson博士）。训练 在这三个领域将通过教学和应用活动来实现，参与国家 会议和机构以及心理会议。 Szlyk博士将应用培训期间获得的技能 进行研究项目以适当适应和测试黑色的MHealth干预的活动 美国人有Oud Plus Comd。在黑人美国人中，与阿片类药物有关的死亡率继续上升 美国。这些死亡通常集中在中型大都市，例如圣路易斯， 密苏里州，这项研究的设定。然而，很少有干预措施适合黑色的独特需求 客户；没有人解决他们加重的过量风险通常会因COMD而加重，而COMD的可能性下降了 为了恢复成功。此外，黑人人遇到了挽救救生的障碍，例如 由于结构性种族主义，OUD的药物（MOUD）。为了解决这一差距，K01研究项目将 综合公共卫生关键种族实践，实施科学和以用户为中心的设计策略 适当地适应了与Oud Plus Comd的黑人美国人的MHealth干预措施。中央 假设是对MHealth干预的适应将改善黑人的参与度和可用性 参与者，提高对MOUD的依从性，并在COMD中的影响下降。这项研究将解决关键 通过1）适应Oud Plus Comd的黑人的MHealth干预措施的差距； 2） 确定障碍和促进者在服务的利益相关者之间实施MHealth干预措施 黑人与oud plus comd; 3）检查改编的MHealth干预措施的初步效率。 这些数据将为未来R01应用程序的较大RCT的设计提供信息。 Szlyk博士的培训和 拟议的研究将在华盛顿大学的杰出知识环境中进行 医学院将为她提供大量资源来实现她的目标。