Training Program in Tuberculosis and HIV Research in Ghana

加纳结核病和艾滋病毒研究培训计划

• 批准号: 9324379
• 负责人: Awewura Jacob Kwara
• 金额: $ 29.84万
• 依托单位: UNIVERSITY OF FLORIDA
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-01 至 2020-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9324379
• 关键词: Acquired Immunodeficiency Syndrome; Address; Area; Basic Science; Behavioral Sciences; Caring; Cause of Death; Cessation of life; Clinical Sciences; Communities; Country; Detection; Discipline; Doctor of Philosophy; Educational workshop; Epidemiology; Funding; Ghana; Goals; Grant; HIV; Health Services; Health Services Research; Health system; Human; Interdisciplinary Study; Intervention; Master' s Degree; Mentors; Morbidity - disease rate; Multidrug-Resistant Tuberculosis; Persons; Postdoctoral Fellow; Prevention; Public Health; Publications; Research; Research Personnel; Research Priority; Research Training; Services; Social Sciences; South Africa; Technical Expertise; Training; Training Programs; Tuberculosis; USAID; United States National Institutes of Health; Universities; Work; academic program; co-infection; effective therapy; implementation science; institutional capacity; meetings; mortality; novel diagnostics; post-doctoral training; programs

 DESCRIPTION (provided by applicant): Tuberculosis (TB) is a major cause of morbidity and mortality among people living with human immunodeficiency virus (PLHIV) in Ghana. Despite the availability of effective treatment, TB is the leading cause of death in PLHIV. Over 50% of all HIV deaths in Ghana are attributed to TB. Consequently, TB in PLHIV is a key priority for both the National TB Control Programme (NTP) and National AIDS Control Programme (NACP). The gaps in TB and HIV research in Ghana cross several disciplines including epidemiology, basic, clinical, social, behavioral, and implementation sciences, as well public health including health systems and health services research. Thus, a multidisciplinary research program is necessary to address yet unanswered and emerging questions that could transform TB prevention and care programs. At a planning meeting in Ghana to develop this application, academics, program managers and community stakeholders identified limited human and institutional research capacity as key barriers to address challenges in areas such as: TB prevention, case detection (including multi-drug resistant TB), integration of TB and HIV services, programmatic rollout of new diagnostics and interventions, as well as health services strengthening including financing. This proposal builds on 10 years of collaborative research between Brown and University of Ghana that led to NIH and USAID grant funding, as well as important publications in the field. The long-term goal of this application is to strengthen institutional capacity at the University of Ghana for multidisciplinary research with a focus on addressing TB/HIV research priorities. This goal will be achieved through a mix of research training programs in key disciplines. The specific objectives of the program are: (1) To implement a long-term research training program that will lead to a critical mass of researchers in the focus area of TB/HIV coinfection. Degree and post-doctoral training depending on the needs of the trainee will be undertaken at University of Ghana, Brown or at selected Universities in South Africa. (2) To promote and implement mentored research in basic, clinical, social, and implementation sciences, as well as health services research with a focus on TB/HIV priorities in Ghana. (3) Implement medium-term training to gain key technical expertise, as well as in-country short-term research training workshops in partnership with NTP and NACP leading to enhanced care of persons with TB/HIV coinfection. At the end of the 5-year training period, we expect to train PhD and Masters Degree candidates, postdoctoral fellow and short-term trainees with complimentary expertise who will develop and implement independent high-quality research relevant to TB and HIV control in Ghana. Ultimately, the work of trainees and their research collaborators will establish a center of excellence for TB/HIV research at the University of Ghana.

 描述（由申请人提供）：结核病 (TB) 是加纳人类免疫缺陷病毒 (PLHIV) 感染者发病和死亡的主要原因，尽管有有效的治疗方法，但结核病仍然是导致 PLHIV 感染者死亡的主要原因。占全部的 50% 加纳的艾滋病毒死亡归因于结核病，艾滋病毒感染者中的结核病是国家结核病控制计划（NTP）和国家艾滋病控制计划（NACP）的重点。加纳的结核病和艾滋病毒研究存在多个学科的差距。流行病学、基础科学、临床科学、社会科学、行为科学和实施科学，以及公共卫生，包括卫生系统和卫生服务研究。因此，有必要采取多学科研究计划来解决可能改变结核病预防的尚未解答和新出现的问题。在加纳举行的开发该应用程序的规划会议上，学者、项目经理和社区利益相关者认为，有限的人力和机构研究能力是应对结核病预防、病例检测（包括多种药物）等领域挑战的主要障碍。该提案建立在布朗大学和加纳大学十年合作研究的基础上，该研究获得了美国国立卫生研究院和美国国际开发署的资助。资金，还有作为该领域的重要出版物。该应用程序的长期目标是加强大学的机构能力。 加纳的多学科研究重点是解决结核病/艾滋病毒研究优先事项，该目标将通过关键学科的混合研究培训计划来实现。该计划的具体目标是：（1）实施长期研究培训。该计划将根据受训者的需要，在加纳布朗大学或南部选定的大学进行学位和博士后培训，该计划将在结核病/艾滋病毒双重感染的重点领域培养大量研究人员。非洲。 (2) 促进和实施辅导。基础、临床、社会和实施科学方面的研究，以及以加纳结核病/艾滋病毒优先事项为重点的卫生服务研究 (3) 实施中期培训以获得关键技术专业知识以及国内短期培训。与 NTP 和 NACP 合作举办长期研究培训讲习班，以加强对结核病/艾滋病毒合并感染者的护理。在 5 年培训期结束时，我们预计将培训博士和硕士学位候选人、博士后研究员和短期人员。具有免费专业知识的学员将在加纳开发和实施与结核病和艾滋病毒控制相关的独立高质量研究，最终，学员及其研究合作者的工作将建立一个中心。 加纳大学在结核病/艾滋病毒研究方面表现出色。