Fiber Delivery of CO2 Lasers for Laryngeal Carcinoma

用于喉癌的 CO2 激光器的光纤传输

• 批准号: 6786905
• 负责人: WESLEY A KING
• 金额: $ 14.31万
• 依托单位: OMNIGUIDE, INC.
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-05-07 至 2004-10-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6786905
• 关键词: bioengineering /biomedical engineering; biomedical equipment development; carbon dioxide; fiber optics; larynx; larynx neoplasms; laser therapy; lasers; microsurgery; polymers; surgery; technology /technique development

DESCRIPTION (provided by applicant): The objective of this SBIR proposal is to improve the treatment options for laryngeal carcinoma by developing a fiber enabled CO2 laser system for laryngeal minimally invasive surgery. Current treatments involve radiotherapy, chemotherapy, and surgical procedures either through open surgery or through a laryngoscope. The surgeon has several operating tools at his disposal. These include cold steel surgical instruments, as well as laser beams, which can be used through the laryngoscope. The CO2 laser is the predominant laser tool for these types of surgeries. There is currently no adequate fiber for delivering CO2 laser for these medical procedures. Accordingly, CO2 laser systems utilize rigid lens and mirror systems to deliver the laser beam to the treated tissue. Introduction of a fiber enabled CO2 laser system will enable tangential cutting, easier manipulation of tissue, higher precision, and most importantly, the ability to reach previously inaccessible tissue, for example in the lower airway. While several different fibers have been tried for CO2 laser delivery, including chalcogenide, polycrystalline and hollow-core metal-coated fibers, none of them have been able to fulfill the entire set of specifications for this application. OmniGuide Communications (OGCI) has developed a new approach for the fabrication of photonic bandgap fibers, based on technology it has exclusively licensed and transferred from MIT. In this Project (Phase I and II) OGCI will leverage its unique technology to develop a fiber that will meet the specifications for laryngological surgery. Phase I will focus on the development of a prototype fiber. Phase II will focus on system integration. Our commercial front, OGCI will collaborate with Lumenis, the world leader in medical laser systems. Our academic partners include both MGH and MEEI. The final goal of this Project is to bring a fiber enabled CO2 laser system for laryngology to market.

描述（由申请人提供）：该SBIR提案的目的是通过开发启用纤维的二氧化碳激光系统来改善喉癌的治疗选择，以用于喉微创手术。当前的治疗涉及通过开放手术或通过喉镜进行放疗，化学疗法和外科手术。外科医生可以使用几种操作工具。其中包括可通过喉镜使用的冷钢手术仪器以及激光束。二氧化碳激光器是这些类型手术的主要激光工具。目前尚无足够的纤维来为这些医疗程序提供CO2激光。因此，二氧化碳激光系统利用刚性镜头和镜像系统将激光束传递到处理的组织。引入启用纤维的二氧化碳激光系统将实现切线切割，更容易对组织进行操纵，更高的精度，最重要的是，可以在下部气道中进行以前无法接近的组织。尽管已经尝试了几种不同的纤维进行二氧化碳激光递送，包括硫元化物，多晶和空心核金属涂层纤维，但它们都无法满足此应用程序的整个规格。 Omniguide Communications（OGCI）开发了一种基于技术的技术，用于制造光子带纤维纤维的新方法。在这个项目（第一阶段和第二阶段）中，OGCI将利用其独特的技术来开发符合喉部手术规格的纤维。第一阶段将专注于原型纤维的开发。第二阶段将专注于系统集成。我们的商业阵线OGCI将与医疗激光系统世界领导者Lumenis合作。我们的学术合作伙伴包括MGH和MEEI。该项目的最终目标是将启用纤维的二氧化碳激光系统用于市场。