Endometrial Mosaic Creation Via Visual Motion Tracking

通过视觉运动跟踪创建子宫内膜马赛克

• 批准号: 6832977
• 负责人: Ananth Natarajan
• 金额: $ 20.19万
• 依托单位: INFINITE BIOMEDICAL TECHNOLOGIES, LLC
• 依托单位国家: 美国
• 财政年份: 2004
• 资助国家: 美国
• 起止时间: 2004-09-17 至 2005-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6832977
• 关键词: bioimaging /biomedical imaging; clinical research; computer system design /evaluation; digital imaging; endometrium; endoscopy; human subject; hysterectomy; phantom model; technology /technique development; uterus

DESCRIPTION (provided by applicant): Hysteroscopic imaging is an important diagnostic tool for the evaluation of the uterus. However, manipulation of the scope to serially visualize the entire endometrial cavity is technically challenging and is subject to a steep learning curve. This motivated our company to design the Endometrioscope, which uses an omni-directional tip, dewarping software, and a servomotor to produce a single visual map of the endometrium in an automated fashion. We now propose to investigate the use of visual motion tracking to create a mosaic of the endometrial cavity. This technology will offer three key advantages. First, we will be able to compensate for motion beyond simple linear displacement of the lens (such as rotation, deformation and scaling). Second, the need for a bulky mount and servomotor will be eliminated as the software tracks the free hand movement of the scope. Third, imaging of the uterine horns will become possible as lateral movement of the scope is interpreted by the software. Our Phase I effort involves development of the motion tracking and mosaicing software. We will then evaluate the technology in a phantom target and finally during an ex-vivo study of human uteri obtained immediately following hysterectomy. If successful, we envision a Phase II effort focused on the development and testing of a clinical grade prototype. It is our long-term goal to provide the gynecologist with an office-based tool to visually investigate the endometrium.

描述（由申请人提供）： 宫腔镜成像是评估子宫的重要诊断工具。但是，操纵范围以串行可视化整个子宫内膜腔的序列在技术上具有挑战性，并且会遇到陡峭的学习曲线。这促使我们公司设计了使用Omni方向提示，脱水软件和伺服电机的子宫内膜镜，以自动化的方式生产单个子宫内膜的单一视觉地图。 现在，我们建议研究视觉运动跟踪的使用以创建子宫内膜腔的镶嵌物。该技术将提供三个关键优势。首先，我们将能够补偿透镜简单线性位移之外的运动（例如旋转，变形和缩放）。其次，随着软件跟踪示波器的自由移动，将消除对笨重的安装和伺服电机的需求。第三，随着软件解释示波器的横向运动，子宫角的成像将成为可能。 我们的第一阶段努力涉及运动跟踪和镶嵌软件的开发。然后，我们将在幻影靶标中评估该技术，最后在子宫切除术后立即获得的人子宫的前研究中。 如果成功的话，我们设想了一项重点介绍临床级原型的开发和测试的II期努力。我们的长期目标是为妇科医生提供基于办公室的工具，以视觉研究子宫内膜。