Expanding HIV testing among Ugandan adults who utilize traditional healers

在使用传统治疗师的乌干达成年人中扩大艾滋病毒检测范围

基本信息

批准号：
9349310
负责人：
Radhika Lu Sundararajan
金额：
$ 18.76万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN DIEGO
依托单位国家：
美国
项目类别：
财政年份：
2017
资助国家：
美国
起止时间：
2017-07-05 至 2021-06-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9349310
关键词：
AIDS/HIV problem Accounting Acquired Immunodeficiency Syndrome Adult Africa South of the Sahara African Applications Grants Applied Research Area Attitude Award Bedside Testings Birth Capital Caring Characteristics Cities Client Collaborations Communities Community Health Control Groups Country Cross-Sectional Studies Data Demographic Factors Development Early Diagnosis Educational workshop Epidemic Epidemiology Foundations Goals HIV HIV Infections HIV antiretroviral HIV diagnosis HIV risk Health Care Costs Health behavior Healthcare Human immunodeficiency virus test Incidence Infection Instruction Intervention Intervention Studies Interview K-Series Research Career Programs Knowledge Link Location Longitudinal cohort Mentored Patient-Oriented Research Career Development Award Mentors Mentorship Methods Modeling Morbidity - disease rate NIH Office of AIDS Research National Institute of Mental Health Outcome Study Patients Physicians Play Population Positioning Attribute Predictive Factor Prevalence Provider Public Health Randomized Reading Research Research Design Research Methodology Research Personnel Research Priority Research Training Resources Role Rural Sampling Science Services Shapes Site Surveys Technology Testing Training Training Activity Uganda United States National Institutes of Health Universities Visit Work antiretroviral therapy base behavior test biomedical facility care seeking career data format design experience healing healthcare community improved innovation mortality novel patient oriented point of care preference prevention service primary outcome prospective responsible research conduct secondary outcome sexually active skills social stigma spiritual healing theories transmission process

项目摘要

PROJECT SUMMARY The purpose of the proposed Mentored Patient-Oriented Career Development Award (K23) is to provide the candidate with training and research experiences that will promote her development to independent researcher as an HIV interventionist, specializing in expanding HIV care to communities who utilize Traditional Healers rather than biomedical facilities. The proposed training will provide her with the opportunity to develop knowledge and skills in: 1) quantitative methods needed to analyze cross-sectional, longitudinal and cohort data; 2) mixed-methods approaches to studying HIV and modeling HIV-related health behavior; and 3) theory, design and implementation of socio-structural interventions. Training activities will include didactic coursework and specific workshops, directed readings and one-on-one tutorials with mentors, and instruction in the responsible conduct of research. The candidate will receive mentorship from a Training Team comprised of globally renowned experts in the fields of HIV epidemiology, mixed methods research, and socio-structural intervention implementation in low-resource settings. Her applied research training will take place in Mbarara, Uganda in collaboration with Mbarara University of Science and Technology. Mbarara District is a rural region, approximately 275 kilometers southwest of the capital city of Kampala, with an HIV prevalence of nearly twice the national average (12%). Prior research in Mbarara has demonstrated the importance of Traditional Healers in providing healthcare for communities in this area, but little is known about Traditional Healer practices or rates of HIV testing (or HIV infection) among their clients. Specific aims of this study are to: 1) identify key socio-structural factors that frame HIV testing behaviors among Ugandan adults who utilize Traditional Healers; 2) investigate acceptability of providing point-of-care HIV testing at Traditional Healer practice locations; and 3) develop and pilot a prospective HIV testing intervention among Traditional Healer patients to promote earlier diagnosis. Results will generate effect estimates for parameters needed to inform power calculations for a subsequent, large-scale cluster-randomized HIV testing intervention at Traditional Healer practice locations, and will position the candidate to develop an R01 application for submission to NIMH at the end of the award period. The proposed work represents a high priority research topic designated by the NIH Office of AIDS Research to “reduce incidence of HIV/AIDS … [by] developing, testing, and implementing strategies to improve HIV testing and entry into prevention services”.

项目概要拟议的以患者为导向的职业发展奖（K23）的目的是提供具有培训和研究经验的候选人将促进她发展为独立研究员作为艾滋病毒干预专家，专门致力于将艾滋病毒护理扩展到利用传统治疗师的社区而不是生物医学设施，拟议的培训将为她提供发展的机会。知识和技能：1）分析横断面、纵向和队列所需的定量方法数据；2) 研究艾滋病毒和模拟艾滋病毒相关健康行为的混合方法；社会结构干预措施的设计和实施将包括教学课程。以及特定的研讨会、定向阅读和导师一对一的辅导，以及候选人将接受由以下人员组成的培训团队的指导。 HIV流行病学、混合方法研究和社会结构领域的全球知名专家她的应用研究培训将在资源匮乏地区的姆巴拉拉进行。乌干达与姆巴拉拉科技大学合作，姆巴拉拉区是一个农村地区，位于首都坎帕拉西南约 275 公里处，艾滋病毒感染率是其近两倍姆巴拉拉之前的研究已经证明了传统治疗师的重要性（12%）。为该地区的社区提供医疗保健，但人们对传统治疗师的做法或了解甚少本研究的具体目的是：1) 确定关键因素。影响使用传统方法的乌干达成年人艾滋病毒检测行为的社会结构因素 2) 调查在传统治疗师实践中提供护理点艾滋病毒检测的可接受性地点；3) 在传统治疗者患者中制定和试点前瞻性艾滋病毒检测干预措施促进早期诊断。结果将产生影响功率所需参数的估计。传统治疗师随后进行的大规模集群随机艾滋病毒检测干预的计算实践地点，并将帮助候选人开发 R01 申请，提交给 NIMH 拟议的工作代表了 NIH 指定的高度优先研究课题。艾滋病研究办公室“减少艾滋病毒/艾滋病的发病率……[通过]制定、测试和实施 “改善艾滋病毒检测和进入预防服务的策略”。