Research Training for Physician-Scientists in Gastrointestinal Oncology

胃肠肿瘤学医师科学家研究培训

• 批准号: 9307746
• 负责人: George Miller
• 金额: $ 26.07万
• 依托单位: NEW YORK UNIVERSITY SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9307746
• 关键词: Physicians; Research Training; Scientist; gastrointestinal; oncology

 DESCRIPTION (provided by applicant): This application seeks to establish a new NIH-funded T32 program to train the next generation of physician- scientists in gastrointestinal oncology. We believe that physician-scientists armed with rigorous research training are necessary to discover and translate new advances in gastrointestinal oncology as well as to investigate critical issues facing delivery of cancer care to patients. Our trainees will be drawn from NYU's renowned clinical fellowship programs in Medical Oncology or Gastroenterology or top-notch residency programs in Radiation Oncology or Surgery. Recruiting individuals from underrepresented minority groups will be paramount. Trainees will take a 2 year hiatus from clinical activities to engage in intensive full-time training in GI cancer research. Our proposed program will have 2 distinct tracks: (i) a Basic/Translational Science track aimed at individuals who wish to direct their own basic science laboratory in GI oncology or individuals who want to lead translational research programs that comfortably interface between the pre-clinical laboratory and clinical investigation and (ii) a Population Sciences tract for trainees who seek careers as cutting edge GI cancer clinical trialists or in the diverse fields of population science such as cancer epidemiology, comparative effectiveness, disparities, or outcomes research. The two tracks will be united through a weekly 2-hour core curriculum covering essential topics in GI cancer and critical lessons for cancer physicians embarking on independent investigative careers. The track-specific program for our Basic/Translational Science track will consist of two years of individualized mentored research in faculty laboratories, enhanced by a strong parallel didactic program in cancer biology. The Population Sciences track will be centered on a rigorous Masters-level curriculum that teaches clinical trial design, epidemiology, comparative-effectiveness, and outcomes research methodologies along with a mentored research project based in population sciences. Thus, physician-trainees will train intensively in basic or translational GI oncology or population sciences and thereby acquire the necessary skills to head a basic or translational laboratory, lead innovative clinical trials, and/or develop a population science program. We plan to enroll 3 new post-doctoral candidates annualy for a steady-state of 6 trainees at any given time. Our program will be led by a cadre of mentors with significant accomplishments and impeccable reputations in cancer research and stellar training records. The program will be supported by the rich Multidisciplinary GI Cancer Program at NYU which is a significant institutional strength that currently houses ~35 clinical trials in GI oncolgy. The aim of the fellowship will be to graduate physician-scientists armed with the capacity and credentials to lead their own research programs and eventually become leaders and role models in investigative GI oncology. We expect that all our graduates will finish their training armed with well-developed K-level grants to bring to their first academic appointment and we expect this program will become the paradigm for training physician-investigators in GI cancer research.

 描述（由申请人提供）：本申请旨在建立一个由 NIH 资助的新 T32 计划，以培训胃肠道肿瘤学领域的下一代医师科学家。我们认为，需要接受严格的研究培训的医师科学家才能发现和转化新的技术。我们的学员将来自纽约大学著名的医学肿瘤学或胃肠病学临床研究项目。或放射肿瘤学或外科领域的一流住院医师计划 招募来自代表性不足的少数群体的人员将至关重要。 2 个不同的轨道：(i) 基础/转化科学轨道，针对希望指导自己的胃肠道肿瘤学基础科学实验室的个人，或希望领导能够在临床前研究和临床前研究之间轻松衔接的转化研究项目的个人实验室和临床调查和（ii）人口科学手册，供那些寻求成为尖端胃肠道癌症临床试验员或人口科学不同领域（如癌症流行病学、比较有效性、差异或结果研究）的学员使用。这两个方向将。通过每周 2 小时的核心课程，涵盖胃肠道癌症的基本主题以及为从事独立研究职业的癌症医生提供的重要课程，我们的基础/转化科学轨道的具体计划将包括两年的个性化指导研究。在教师实验室，人口科学课程将以严格的硕士水平课程为中心，教授临床试验设计、流行病学、比较有效性和结果研究方法以及指导研究。因此，实习医生将接受基础或转化胃肠道肿瘤学或人口科学方面的强化培训，从而获得领导基础或转化实验室、领导创新临床试验和/或开发人群所需的技能。我们计划每年招收 3 名新的博士后候选人，以保持 6 名学员的稳定状态。我们的项目将由一批在癌症研究和培训记录方面取得重大成就和无可挑剔声誉的导师领导。该项目将得到纽约大学丰富的多学科胃肠道癌症项目的支持，该项目是一个重要的机构优势，目前拥有约 35 项胃肠道肿瘤学临床试验。该奖学金的目的是培养具备这种能力的医师科学家。和证书来领导自己的研究项目，并最终成为研究性胃肠道肿瘤学的领导者和榜样。我们期望我们所有的毕业生都将在完善的 K 级补助金的帮助下完成他们的培训，以完成他们的第一个学术任命，我们希望这一点。计划将成为培训胃肠道癌症研究医师研究人员的范例。