Mentoring Multidisciplinary Patient-Oriented Research in Engagement in HIV Care

指导参与艾滋病毒护理的多学科、以患者为导向的研究

• 批准号: 9411533
• 负责人: Elvin H. Geng
• 金额: $ 18.81万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-07-01 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9411533
• 关键词: Acquired Immunodeficiency Syndrome; Address; Advisory Committees; Africa; African; Attention; Caring; Case Management; Clinic; Clinic Visits; Clinical; Communities; Complement; Computerized Medical Record; Country; Data; Databases; Epidemic; Epidemiology; Evaluation; Event; Exhibits; Feedback; Foundations; Funding; HIV; Health; Incidence; Individual; Infectious Diseases Research; International; Intervention; Interview; Investments; K-Series Research Career Programs; Kenya; Lead; Mental disorders; Mentors; Mentorship; Mid-Career Clinical Scientist Award (K24); Midcareer Investigator Award in Patient-Oriented Research; Modeling; Outcome; Parents; Patient Care; Patients; Pattern; Perception; Persons; Play; Population; Postdoctoral Fellow; Provider; Public Health; RNA; Randomized; Research; Research Activity; Research Infrastructure; Research Personnel; Resources; Risk Factors; Role; Sampling; San Francisco; Science; Scientist; Site; Socioeconomic Status; Students; Substance abuse problem; Surveys; System; Time; Training; Training Support; Uganda; United States Health Resources and Services Administration; United States National Institutes of Health; Universities; Viremia; Visit; Work; Zambia; Zimbabwe; base; career; cohort; design; evidence base; experience; follow-up; health care delivery; housing instability; improved; meetings; multidisciplinary; patient oriented research; pre-doctoral; prevent; programs; psychologic; resilience; safety net; senior faculty; shared decision making; skills; standard of care; success; treatment program; virology; ward

Project Summary I seek support from a K24 Award to build a mentoring program in patient oriented research to enhance engagement in HIV treatment globally. At present, I lead robust research activities supported by diverse mechanisms (including NIH R01 & U01, HRSA, and Gates Foundation) with over 1.5 million dollars a year of direct funding. I am leading work in the US as well as four African countries (Uganda, Kenya, Zimbabwe and Zambia), some within established scientific networks (e.g., International Epidemiologic Databases to Evaluate AIDS). This growing research portfolio has created abundant opportunities to mentor trainees, including post-doctoral fellows supported by T32 and D43 mechanisms, pre-doctoral students, and those from international partner organizations (e.g., Makerere University in Kampala). With support from a K24 Award, I would offer a comprehensive but adaptable blueprint for mentorship, with a focus on guiding investigators across two critical thresholds: first, for fellows establishing a research career through obtaining a K23 Career Development Award, and second, sustaining a research career through subsequent R01 level funding. My mentorship model is based both on individual meetings as well as assembly of a team of mentors who can meet diverse technical, professional and personal needs. In addition, within UCSF, I plan to integrate the proposed mentoring with existing resources for training supported by the UCSF CTSI and the Center for AIDS Research. Outside of UCSF, I will introduce mentees into flourishing research consortia in which I am active (e.g., IeDEA and CNICS) as well as into public health implementing organizations (e.g., Center for Infectious Disease Research in Zambia) where they can access multi-site data and develop independent scientific projects and professional relationships. To improve my mentoring, I will form an advisory committee of senior faculty at UCSF who will offer feedback and evaluation on my mentoring using evidence-based metrics of success. At present, I receive eight to ten requests for mentorship each year and have only been able to accept two to three because my effort is fully taken by project specific research roles, clinical duties and administrative obligations. Support from a K24 will allow me to accept up to eight total mentees a year. This would include serving as primary mentor to 1 post-doctoral fellow and secondary mentor to 2-3 fellows and other pre-doctoral residents and students. In particular, a K24 will allow me to dedicate more time to the most intensive mentorship relationships with post doctoral fellows competing for K23 Career Development Awards as well those seeking transition from K23 to R01 level funding and full scientific independence.

项目概要 我寻求 K24 奖的支持，建立一个以患者为导向的研究指导计划， 加强全球艾滋病毒治疗的参与。目前，我领导着稳健的研究活动 得到多种机制的支持（包括 NIH R01 和 U01、HRSA 和盖茨基金会） 每年超过 150 万美元的直接资金。我在美国领导工作 四个非洲国家（乌干达、肯尼亚、津巴布韦和赞比亚），其中一些国家属于既定国家 科学网络（例如，评估艾滋病的国际流行病学数据库）。这 不断增长的研究组合为指导学员创造了丰富的机会，包括 T32、D43机制资助的博士后、博士前学生等 来自国际合作伙伴组织（例如坎帕拉的麦克雷雷大学）。有支持 从 K24 奖中，我将提供一个全面但适应性强的指导蓝图，其中包括： 重点是引导研究人员跨越两个关键门槛：首先，研究员建立一个 通过获得 K23 职业发展奖来促进研究生涯，其次，维持 研究生涯通过随后的 R01 级别资助。我的导师模式基于 单独的会议以及导师团队的集合，他们可以满足不同的技术、 专业和个人需求。此外，在 UCSF 内部，我计划整合拟议的 利用 UCSF CTSI 和中心支持的现有培训资源进行指导 艾滋病研究。在加州大学旧金山分校之外，我将向学员介绍蓬勃发展的研究联盟 我积极参与其中（例如 IeDEA 和 CNICS）以及公共卫生实施 他们可以访问的组织（例如赞比亚传染病研究中心） 多站点数据并开发独立的科学项目和专业关系。到 改善我的指导，我将组建一个由加州大学旧金山分校高级教师组成的咨询委员会，他们将提供 使用基于证据的成功指标对我的指导进行反馈和评估。现在， 我每年都会收到八到十个指导请求，但只能接受其中两个 到三，因为我的努力完全被项目特定的研究角色、临床职责和 行政义务。 K24 的支持将使我能够接受最多八名学员 一年。这将包括担任 1 名博士后研究员的主要导师和 指导 2-3 名研究员和其他博士前住院医师和学生。特别是，K24 将 让我能够将更多的时间投入到与博士后最密切的指导关系上 竞争 K23 职业发展奖的研究员以及寻求从 K23 至 R01 级别的资助和完全的科学独立性。