HD2A Research Adoption Support Center (RASC)

HD2A 研究采用支持中心 (RASC)

• 批准号: 10708980
• 负责人: WILLIAM C BECKER
• 金额: $ 312.38万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-30 至 2027-08-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10708980
• 关键词: Address; Adoption; Attitude; Awareness; Case Study; Catalogs; Collaborations; Communities; Complex; Consensus; Data; Development; Dimensions; Dissemination and Implementation; Economics; Ensure; Epidemic; Equity; Evaluation; Evidence based intervention; Evidence based practice; Faculty; Goals; Harm Reduction; Health; Human; Intervention; Intervention Studies; Investments; Knowledge; Leadership; Learning; Life; Measurement; Measures; Methodology; Methods; Modeling; Monitor; National Institute of Drug Abuse; Opiate Addiction; Opioid; Outcome; Pain; Pain management; Persons; Policies; Prevention; Prevention strategy; Public Health; Publications; Qualifying; Records; Research; Research Design; Research Personnel; Research Project Grants; Resources; Scientist; Services; Site; Specific qualifier value; Standardization; Stimulant; Substance Use Disorder; System; Technical Expertise; Terminology; Theoretical model; Thinking; Translating; Translational Research; United States National Institutes of Health; addiction; community living; data harmonization; data infrastructure; design; dissemination science; evidence base; experience; formative assessment; health care availability; implementation evaluation; implementation research; implementation science; implementation strategy; implementation study; implementation tool; improved; innovation; knowledge base; online resource; opioid epidemic; opioid mortality; opioid use disorder; overdose death; overdose prevention; prevent; program dissemination; programs; provider intervention; real world application; research study; resource guides; response; service delivery; social capital; social stigma; stem; substance use; substance use prevention; symposium; translational barrier

OVERALL: PROJECT SUMMARY/ABSTRACT In response to the National Institutes of Health RFA-DA-22-050, we herein propose a HEAL Data2Action Research Adoption Support Center (RASC). The main purpose of the RASC is to stem the tide of overdose death in the US by leading a scientifically-driven support endeavor designed to effectively translate evidence- based interventions for substance use disorders and pain. Presently, overdose death escalates. Dissemination and implementation (D&I) science is the methodological bridge to both the scientific and public health gaps. Yet D&I science is understudied and underutilized in response to the opioid epidemic. Emblematic of heightened awareness for D&I scientific potential, the HEAL D2A Program will be launched. The program features 10-12 Innovation Projects, and, in addition to the RASC, two additional centers: Modeling and Economic Resource Center and Data Infrastructure Support Center. The RASC will optimize and elevate the D&I capability of the overall HD2A program. In this OVERALL component, we document how the RASC is organized into four synergistic and dynamic cores: Administrative, Substance Use Implementation Support Core, Pain Implementation Support Core, and a Research & Evaluation Core. Three overarching specific aims are strategically ordered across the RASC and all its cores follows: To ASSESS the current state of the HD2A Innovation Projects on D&I research capability, and develop an empirically-based catalog of evidence-based and emerging interventions for substance use disorders and pain; to ASSIST on how Innovation Projects can improve D&I methods and measures through on demand technical assistance and the use of an innovative Implementation Support Plan, and to develop SUD and Pain Intervention D&I Resource Guides; and lastly, to ADVANCE the HD2A Innovation Projects toward greater potential for scalability and sustainment. The RASC is led by 4 MPIs with demonstrated track records of D&I research and practice in the fields of substance use and pain interventions: McGovern (Stanford), S. Becker (Brown), W. Becker (Yale) and Brown (Northwestern). The MPIs are joined by complementary expert core co-directors, and have assembled an unmatched roster of highly-qualified leaders in these fields—carefully selected, organized and ready to provide the necessary implementation support across the HD2A program. This RASC meets all the specified requirements as outlined in the RFA. What distinguishes this RASC is our bold ambition to enhance not only the D&I capability of the HEAL HD2A program, but to influence the field far beyond the confines of the HD2A initiative. We intend to elevate the D&I paradigm of substance use and pain intervention research, and thereby ensure ubiquitous and equitable access to proven interventions by the people and communities who need them the most.

总体：项目摘要/摘要 为了回应美国国立卫生研究院RFA-DA-22-050，我们在这里提议heal data2Action 研究收养支持中心（RASC）。 RASC的主要目的是阻止过量的潮流 通过领导科学驱动的支持努力，旨在有效地转化证据 - 基于药物使用障碍和疼痛的干预措施。目前，过量死亡升级。传播 实施（D＆I）科学是通往科学和公共卫生差距的方法论上的桥梁。 然而，D＆I科学因反应阿片类药物流行而被理解和利用不足。象征 将提高对D＆I科学潜力的意识，HEAL D2A计划将启动。该程序 具有10-12个创新项目，除了RASC之外，还具有两个其他中心：建模和 经济资源中心和数据基础设施支持中心。 RASC将优化并提升 D＆I整体HD2A计划的功能。在这个整体组件中，我们记录了RASC的方式 组织成四个协同和动态的核心：行政，药物使用实施支持 核心，疼痛实施支持核心以及研究与评估核心。三个总体特定目标 在整个RASC及其所有核心上进行战略性订购：评估HD2A的当前状态 关于D＆I研究能力的创新项目，并开发了基于循证的基于经验的目录 以及新兴的物质使用障碍和疼痛的干预措施；协助创新项目如何 通过按需按需技术帮助改善D＆I方法和措施，并使用创新 实施支持计划，并制定SUD和疼痛干预D＆I资源指南；最后，要 推进HD2A创新计划，以更大的潜力可伸缩和维持。 rasc是 由4个MPI领导，在使用物质使用和 疼痛干预：麦戈文（斯坦福），S。Becker（Brown），W。Becker（Yale）和Brown（Northwestern）。这 MPI由完善的专家核心联合指导加入，并组装了无与伦比的名册 这些领域的高度合格的领导者 - 精心选择，有组织并准备提供必要的 HD2A计划的实施支持。此RASC符合所有指定的要求 在RFA中概述。这种RASC的区别是我们大胆的野心，不仅可以增强D＆I能力 在HEL HD2A计划中，但是要影响远远超出HD2A计划的范围的领域。我们打算 提升药物使用和疼痛干预研究的D＆I范式，从而确保无处不在 公平地证明最需要他们的人和社区的干预措施。