UTMB Clinical and Translational Science Award

UTMB 临床和转化科学奖

• 批准号: 9270638
• 负责人: MARK R HELLMICH
• 金额: $ 26.18万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2020-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9270638
• 关键词: Academic Training; Address; Assessment tool; Award; Basic Science; Behavior Therapy; Clinical; Clinical Research; Clinical Sciences; Clinical Trials; Communication; Competence; Devices; Diagnostic; Discipline; Disease; Doctor of Philosophy; Educational Curriculum; Enrollment; Entrepreneurship; Ethical Issues; Faculty; Fellowship; Funding; Future; Goals; Health; Human; Human Subject Research; Hybrids; Industry; Intervention; Knowledge; Laboratories; Leadership; Letters; Mediation; Medical Students; Mentors; Methods; Modeling; Pharmaceutical Preparations; Positioning Attribute; Postdoctoral Fellow; Program Evaluation; Recruitment Activity; Research; Research Activity; Research Design; Research Infrastructure; Research Project Grants; Research Training; Resources; Rotation; Schools; Science; Student recruitment; Students; TNFSF15 gene; Technical Expertise; Testing; Therapeutic; Training; Training Programs; Training Support; Translational Research; Underrepresented Minority; Work; Workforce Development; base; conflict resolution; graduate student; improved; innovation; multidisciplinary; pre-doctoral; programs; science education; skills; success

ABSTRACT This TL1 Training Core, in support of the UTMB CTSA U54 application, will provide “predoctoral students (3 trainees/year) with a deep orientation to translational science, and postdoctoral fellows (3 scholars/year) with advanced research training aligned with the CTSA's goals of advancing therapeutics (drugs, devices, diagnostics and preventatives), clinical interventions, and behavioral modifications to improve human health.” Existing curricula and training programs at UTMB, as elsewhere, excel at developing discipline-specific knowledge and technical skills, but are less effective at developing the core skills and competencies essential for the effective and efficient practice of team-based translational science; these are: team management, shared leadership, conflict resolution and negotiations, interprofessional communication, entrepreneurship, and the regulatory and ethical issues associated with human subjects research and clinical trials. To address this gap, we will build on our CTSA hub's successful application of a hybrid industry “work team”-academic approach to translational research using a Multidisciplinary Translational Team (MTT) model. We will also use a training model that is based on our successful implementation of a competency-driven curriculum for a new translational PhD program. We will recruit from a sufficiently large pool of trainees in any of our 13 biomedical graduate programs, including a large proportion of underrepresented minorities, which is mirrored by a diverse faculty. Of key importance, the GSBS and the UTMB Provost initiated and fund financial supplements for students recruited as Presidential Scholars to encourage the enrollment of outstanding graduate students. Potential trainees will be advised to pursue laboratory rotations with MTT-based faculty. Once a mentoring team is selected, students and their mentors will apply for training positions (predoctoral fellowship) in the TL1 Training Core. Postdoctoral scholars will be specifically recruited to the program by MTT-based mentors (Program Faculty). Among others, three particularly innovative components of the required curriculum include: 1) the Interprofessional Translational Research Design Course, which includes medical students and PhD students working in teams; 2) the Clinical Encounters Program, which addresses the need for trainees and scholars to be educated in the human health- and disease-related aspects of their research; and 3) dissertation/postdoctoral research projects co-mentored by both scientific and clinical experts. Lastly, our training program's evaluations will use relevant, validated assessment tools such as the Teamwork Competency Test and others. Primary financial resources, space, and staff are committed by UTMB to provide oversight, key core resources, integrative programs and seminars for this Training Core. The Graduate School of Basic Sciences also provides financial and infrastructure support for the Training Core. Lastly, the supporting letter from the UTMB Provost enumerates the current and future commitments to the ITS, which assure the success of this oversight entity for our innovative training program.

抽象的 该 TL1 培训核心支持 UTMB CTSA U54 申请，将提供“博士前学生（3 学员/年）对转化科学有深入的了解，博士后研究员（3名学者/年） 高级研究培训与 CTSA 推进治疗学（药物、设备、 诊断和预防）、临床干预和行为改变，以改善人类健康。” 与其他地方一样，UTMB 现有的课程和培训计划擅长开发特定学科 知识和技术技能，但在发展必要的核心技能和能力方面效果较差 为了有效和高效地实践基于团队的转化科学； 共同领导、冲突解决和谈判、跨专业沟通、创业精神和 与人体研究和临床试验相关的监管和伦理问题。 差距，我们将在 CTSA 中心成功应用混合行业“工作团队”-学术的基础上继续发展 我们还将使用多学科转化团队（MTT）模型进行转化研究。 一种基于我们成功实施能力驱动课程的培训模式 我们将从 13 个生物医学项目中的任何一个中招募足够多的学员。 研究生课程，其中包括很大一部分代表性不足的少数族裔，这反映在多样化的 至关重要的是，GSBS 和 UTMB 教务长发起并资助了教师的财政补贴。 招收学生为总统学者，鼓励优秀研究生招生。 一旦接受指导，潜在的学员将被建议与 MTT 教师一起进行实验室轮换。 团队选定后，学生及其导师将申请 TL1 的培训职位（博士前奖学金） 培训核心。博士后学者将由基于 MTT 的导师专门招募到该项目。 （项目教师）。除其他外，所需课程的三个特别创新的组成部分包括： 1）跨专业转化研究设计课程，包括医学生和博士生 学生团队合作；2) 临床遭遇项目，满足学员的需求； 学者接受人类健康和疾病相关研究方面的教育；3) 由科学和临床专家共同指导的论文/博士后研究项目。 培训计划的评估将使用相关的、经过验证的评估工具，例如团队合作 UTMB 承诺提供能力测试和其他主要财务资源、空间和人员。 该培训核心的监督、关键核心资源、综合计划和研讨会。 基础科学学院还为培训核心提供财政和基础设施支持。 UTMB 教务长的支持信列举了当前和未来对 ITS 的承诺，其中 确保这个监督实体对我们的创新培训计划取得成功。