HIV/AIDS Research and Training in Northern Thailand

泰国北部的艾滋病毒/艾滋病研究和培训

• 批准号: 6666715
• 负责人: THIRA SIRISANTHANA
• 金额: $ 4.95万
• 依托单位: CHIANG MAI UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-30 至 2004-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6666715
• 关键词: AIDS; AIDS education /prevention; HIV infections; health science research support; human immunodeficiency virus 1; southeast Asia; training

DESCRIPTION: Thailand has been successful in preventing the transmission of HIV in commercial sex settings. Despite the decline in HIV incidence, the burden of HIV infection will be a major problem for the coming generation. There are more than 750,000 persons living with HIV/AIDS in Thailand. Transmission in IDUs is still a significant problem, and transmission between spouses and via casual sex is on the rise. Less than 1% of persons living with HIV/AIDS in Thailand are on antiretroviral treatment. The cost of antiretroviral drugs is coming down, and there is a need to train physicians to be familiar with antiretroviral therapy. There is a need to find the best strategy to manage opportunistic infections in the era of antiretroviral therapy. In addition, there is a need to study the molecular epidemiology of HIV-1 in preparation for vaccine trials. The aim of this project is to plan the development of a regional capacity to initiate and sustain an ongoing research effort as well as the development of a regional training center in the prevention and care of HIV/AIDS. Three CIPRA cores namely administrative, laboratory, and training core will be established. The investigators will plan to submit an application for the next level of CIPRA support. It will include research in molecular epidemiology, care of opportunistic infection in the era of antiretroviral treatment, and antiretroviral therapy in children among others. It will also address other behavioral and biomedical (including vaccine) intervention in the prevention and care of HIV/AIDS that are relevant to the country's problems.

描述：泰国已成功地预防了商业性行为场所中艾滋病毒的传播。尽管艾滋病毒发病率下降，但艾滋病毒感染负担将成为下一代的主要问题。泰国有超过 750,000 名艾滋病毒/艾滋病感染者。注射吸毒者中的传播仍然是一个重大问题，配偶之间和通过随意性行为传播的情况正在上升。在泰国，只有不到 1% 的艾滋病毒/艾滋病感染者正在接受抗逆转录病毒治疗。抗逆转录病毒药物的成本正在下降，需要培训医生熟悉抗逆转录病毒治疗。在抗逆转录病毒治疗时代，需要找到管理机会性感染的最佳策略。此外，还需要研究HIV-1的分子流行病学，为疫苗试验做准备。该项目的目的是规划发展区域能力，以启动和维持正在进行的研究工作，并发展预防和护理艾滋病毒/艾滋病的区域培训中心。将建立三个CIPRA核心，即行政、实验室和培训核心。研究人员将计划提交下一级 CIPRA 支持的申请。它将包括分子流行病学研究、抗逆转录病毒治疗时代机会性感染的护理以及儿童抗逆转录病毒治疗等。它还将讨论与该国问题相关的艾滋病毒/艾滋病预防和护理方面的其他行为和生物医学（包括疫苗）干预措施。