Lymphatic Conference

淋巴会议

• 批准号: 9261242
• 负责人: GUILLERMO C OLIVER
• 金额: $ 2万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2017
• 资助国家: 美国
• 起止时间: 2017-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9261242
• 关键词: Animal Model; Area; Basic Science; Biology; Biomedical Engineering; Cardiovascular Diseases; Chicago; Clinical; Clinical Research; Clinical Trials; Collaborations; Defect; Development; Disease; Epigenetic Process; Experimental Models; Fostering; Functional disorder; Generations; Glaucoma; Growth; Health; Heart Diseases; Homeostasis; Hypertension; Illinois; Imaging Device; Immunologic Surveillance; Inflammation; Lipids; Liquid substance; Lymphatic; Lymphatic Diseases; Lymphatic vessel; Lymphedema; Malignant Neoplasms; Metabolism; Modeling; Nanotechnology; Obesity; Paper; Participant; Pathologic; Patients; Physicians; Play; Postdoctoral Fellow; Public Health; Publishing; Regulation; Research; Research Personnel; Role; Scientist; Series; Sodium Chloride; Stem cells; Students; Surface; Therapeutic; Time; Vision; Work; absorption; career; comparative; experience; graduate student; insight; interest; medical schools; meetings; nano; nervous system disorder; novel; posters; programs; symposium; tool

Project Summary This application is to request partial support of the inaugural NAVBO-LE&RN Lymphatic Conference that will take place at Northwestern Medical School in Chicago, Illinois on June 8-11, 2017. Research in lymphatic biology has experienced a dramatic growth within the last 10 years. This can be seen through the increase in the number of investigators, thanks to the emergence of a new generation of researchers, as well as through the increase in the number of investigators who, although working in other topics, have incorporated lymphatic-related questions into their interests. This growth is due, in part, to the identification of critical regulators of lymphatic growth and the availability of animal models, and to a better understanding of the functional roles of the lymphatic vasculature in health and disease. Lymphatic function has been primarily associated with lipid absorption, fluid/macromolecular homeostasis, and immune surveillance, and lymphatic vessel dysfunction has been associated with pathologic conditions such as lymphedema. However, recent work identified novel functional roles of the lymphatic vasculature in metabolism, obesity, inflammation, the regulation of salt storage in hypertension, heart disease, glaucoma and possibly even in some neurological disorders. Therefore, there is a dramatically increasing need for researchers working in a broad spectrum of normal and pathological lymphatic conditions. Along with the growth of the field and recognition of the public health importance of lymphatic diseases, there is a need for more frequent forums to exchange scientific progress and ideas in related topics that could bring together developmental biologists, cancer researchers, physiologists, biomedical engineers, cardiologists, neuroscientists and physicians. Such forums will help to promote the current progress in the identification and better characterization of lymphatic related disorders. Until now, the main lymphatic research conference was the one organized by the GRC every two years since 2004. Although a comparatively young GRC conference, attendance at the meeting has grown steadily since its inception and the number of applications for the last one in 2016, exceeded by 25 the maximum number of allowed participants (200). Accordingly, it has become apparent that there is a need to add a second major biennial lymphatic conference that can alternate with the established GRC. Therefore, this initial Lymphatic Conference will set the tone for those that will follow, as we expect that this series will also become a tradition in years to come. As seen in the proposed program, the selected speakers not only cover many of the major research topics, but will also put a special emphasis on the novel functional areas of lymphatic research, such as metabolism, neurological disorders, vision and cardiovascular diseases. It will also bring together basic and clinical scientists, as we will dedicate two sessions to discuss a variety of lymphatic-related pathological disorders. To make this conference broader and to foster interactions with researchers in other topics, an entire session will be devoted to emerging areas, such as stem cells, epigenetics and nanotechnology.

项目概要 本申请旨在请求首届 NAVBO-LE&RN 淋巴会议的部分支持，该会议将 于 2017 年 6 月 8 日至 11 日在伊利诺伊州芝加哥西北医学院举行。淋巴生物学研究 在过去 10 年里经历了巨大的增长。从数量的增加就可以看出 得益于新一代研究人员的出现以及研究人员数量的增加 虽然从事其他主题但纳入了淋巴相关问题的研究人员数量 进入他们的利益。这种增长部分归因于淋巴管生长的关键调节因子的识别和 动物模型的可用性，以及更好地了解淋巴管系统的功能作用 在健康和疾病方面。淋巴功能主要与脂质吸收有关， 液体/大分子稳态、免疫监视和淋巴管功能障碍已被 与淋巴水肿等病理状况有关。然而，最近的工作发现了新的功能 淋巴管系统在新陈代谢、肥胖、炎症、盐储存调节中的作用 高血压、心脏病、青光眼，甚至可能导致某些神经系统疾病。因此，有一个 对研究广泛的正常和病理淋巴管的研究人员的需求急剧增加 状况。随着该领域的发展和人们对淋巴对公共卫生重要性的认识 疾病，需要更频繁的论坛来交流相关主题的科学进展和想法 可以将发育生物学家、癌症研究人员、生理学家、生物医学工程师聚集在一起， 心脏病专家、神经科学家和医生。此类论坛将有助于推动当前的进展 识别和更好地表征淋巴相关疾病。迄今为止，主要针对淋巴管的研究 该会议是GRC自2004年以来每两年举办一次的会议。 GRC会议自创办以来，参会人数稳步增长 2016 年最后一届的申请数量超过了允许参加人数上限（200 人）的 25 人。 因此，很明显有必要增加第二次两年一次的大型淋巴会议 可以与已建立的GRC交替。因此，这次最初的淋巴会议将为 我们预计该系列也将成为未来几年的传统。正如在 拟议的计划中，选定的演讲者不仅涵盖了许多主要研究主题，而且还将提出 特别强调淋巴研究的新功能领域，例如新陈代谢、神经系统 疾病、视力和心血管疾病。它还将汇集基础科学家和临床科学家，正如我们将 两次会议专门讨论各种与淋巴相关的病理性疾病。为了举办这次会议 为了更广泛地促进与其他主题的研究人员的互动，整个会议将专门讨论新兴领域 领域，如干细胞、表观遗传学和纳米技术。