Planning for a National Non-Communicable Disease Center of Research Excellence

规划国家非传染性疾病卓越研究中心

• 批准号: 9193832
• 负责人: Dirk P Dittmer
• 金额: $ 26.48万
• 依托单位: UNIV OF NORTH CAROLINA CHAPEL HILL
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-09-01 至 2018-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9193832
• 关键词: Achievement; Address; Africa South of the Sahara; Area; Attention; Basic Science; Biometry; Burn Trauma; California; Cardiovascular Diseases; Centers of Research Excellence; Clinic; Clinical; Clinical Trials Cooperative Group; Collaborations; Communicable Diseases; Communities; Comprehensive Cancer Center; Consensus; Core Facility; Country; Development; Disease; Educational process of instructing; Ensure; Environment; Faculty; Funding; Goals; Government; Grant; HIV; Health; Health Policy; Hospitals; Human Resources; Hygiene; Income; Information Systems; Injury; Institution; International; Investments; Kenya; Laboratories; Leadership; Letters; London; Los Angeles; Malawi; Malignant Neoplasms; Measurable; Measures; Medicine; Modeling; Movement; Needs Assessment; North Carolina; Operative Surgical Procedures; Outcome; Output; Ownership; Pathology; Patients; Pediatric Hospitals; Principal Investigator; Procedures; Public Health; Publications; Recording of previous events; Research; Research Activity; Research Infrastructure; Research Personnel; Research Support; Resources; Schools; South Africa; Teaching Hospitals; Training; Training Programs; Translating; Tropical Medicine; Trust; United States National Institutes of Health; Universities; University Hospitals; Zambia; abstracting; anticancer research; base; burden of illness; clinical investigation; college; low and middle-income countries; programs; research facility; response; success; ward

Project Summary Abstract This application is in response to RFA-CA15-007. It comprises a two-year planning period to develop a Malawi Center of Research Excellence for non-communicable diseases (NCDs), focused on cancer, injury, and cardiovascular disease (CVD). These three areas of concentration are of major public health importance with immense unmet need. They have been prioritized by our partner institutions in this application: the Malawi College of Medicine (COM) and Ministry of Health (MOH). Following the intent of the RFA the University of North Carolina (UNC) will serve as the high-income country partner institution for the application, based on its decades-long program in Malawi, long history of collaboration with COM and MOH, and deep involvement in cancer research activities specifically within Malawi. The planning grant will seek to engage US and International partners with significant NCD programs in Malawi, such as UCLA and Baylor College of Medicine, and others. This is a multiple principal investigators application with highly complementary expertise: Satish Gopal (UNC/COM; cancer; clinical investigation); Nyengo Mkandawire (COM; injury; clinical investigation); Mwapatsa Mipando (COM; cardiovascular disease; basic science); Dirk Dittmer (UNC; cancer; basic science). In addition, senior investigators and leadership from government and other supported research programs will participate as key personnel and consultants during the planning period, which leverages an impressive pool of faculty within and outside Malawi. The planning is to develop a center will include administrative, developmental, clinical, laboratory, biostatistics, and implementation cores and which may serve as a resource for the region, e.g. in pathology and surgery training. Partners will be invited during the planning period to contribute to a national plan for each of these, based on existing resources and activities across institutions, as well as new resources and activities that are collectively prioritized. Sustainability of the proposed center and its impact will be ensured by strong ownership from collaborating Malawian partners, including support by the highest levels of COM and MOH. We seek to establish active linkages of collaborating partners within Malawi to international institutions and research networks outside Malawi will allow the center to leverage these external relationships to achieve regional importance in sub-Saharan Africa. Finally, by catalyzing a broad national movement to address a rapidly growing NCD burden, the center will deliver measurable benefits to the people of Malawi.

项目概要 摘要 此申请是为了响应 RFA-CA15-007。它包括一个为期两年的规划期，以开发马拉维 非传染性疾病 (NCD) 卓越研究中心，重点研究癌症、损伤和 心血管疾病（CVD）。这三个重点领域对公共卫生具有重要意义 巨大的未满足的需求。我们的合作机构在此申请中优先考虑了它们：马拉维 医学院 (COM) 和卫生部 (MOH)。遵循 RFA 的意图，大学 北卡罗来纳州 (UNC) 将作为该申请的高收入国家合作机构，基于其 在马拉维开展了长达数十年的项目，与 COM 和 MOH 有着悠久的合作历史，并深入参与 特别是在马拉维境内的癌症研究活动。规划拨款将寻求让美国和 与马拉维重要的非传染性疾病项目合作的国际合作伙伴，例如加州大学洛杉矶分校和贝勒医学院， 和其他人。这是一个多位主要研究者的应用程序，具有高度互补的专业知识：Satish Gopal（UNC/COM；癌症；临床研究）； Nyengo Mkandawire（COM；伤害；临床调查）； Mwapatsa Mipando（COM；心血管疾病；基础科学）； Dirk Dittmer（北卡罗来纳大学；癌症；基础科学）。 此外，来自政府和其他支持的研究项目的高级研究人员和领导将 在规划期间作为关键人员和顾问参与，这利用了令人印象深刻的人才库 马拉维境内外的教师。规划是建立一个中心，包括行政、 发育、临床、实验室、生物统计学和实施核心，可作为资源 对于该地区，例如病理学和外科培训。规划期间将邀请合作伙伴 根据各机构的现有资源和活动，为每一项国家计划做出贡献， 以及集体优先的新资源和活动。拟议中心的可持续性和 马拉维合作伙伴的强有力的自主权将确保其影响力，包括来自 COM 和 MOH 水平最高。我们寻求在马拉维境内建立积极的合作伙伴联系 马拉维以外的国际机构和研究网络将使该中心能够利用这些 外部关系，以实现撒哈拉以南非洲的区域重要性。最后，通过广泛的催化 为了解决快速增长的非传染性疾病负担的全国运动，该中心将为 马拉维人民。