ASTHMA GUIDELINES COMPLIANCE--CLINICAL/COST EFFECTIVENES

哮喘指南合规性——临床/成本效益

• 批准号: 6612716
• 负责人: ANNE L FUHLBRIGGE
• 金额: $ 13.39万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 财政年份: 1999
• 资助国家: 美国
• 起止时间: 1999-07-01 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6612716
• 关键词: asthma; clinical research; emergency care; health care cost /financing; health care service evaluation; health services research tag; hospital utilization; human data; human therapy evaluation; outcomes research; patient care management; quality of life; respiratory disease /disorder therapy; respiratory disorder chemotherapy; statistics /biometry; therapy compliance

This proposal is designed to provide the opportunity for the Principal Investigator (PI) to gain knowledge and skills in medical outcomes, economics and cost effectiveness evaluation under the supervision of an advisory committee comprising a highly qualified sponsor and co-investigators. The PI has exceptional clinical training and has completed a two-year fellowship in respiratory epidemiology at the Channing Laboratory. In addition she has obtained an M.S. in Clinical Epidemiology at the Harvard School of Public Health. This award in combination with the PI's background provides an excellent potential for development of a successful independent research career. The overall scientific goal of this proposal is to determine whether individuals with asthma management that conforms with recommendations published within the National Asthma Education and Prevention Program (NAEPP) Guidelines for the Diagnosis and Management of Asthma, results in an improved clinical outcome and is cost effective relative to individuals whose management does not conform. We propose to use the extensive information available on a cohort of adult and pediatric asthma patients assembled at Harvard Pilgrim Health Care (HPHC) in a retrospective cohort study design. We hypothesize that individuals with asthma pharmacotherapy and non- pharmacologic management (outpatient follow-up and specialist referral, asthma education, peak flow utilization, environmental measures) that conforms with the NAEPP Guidelines will have decreased health care utilization, improved Health Related Quality of Life (HRQL) and will be cost effective when compared with individuals whose management does not conform. This proposal is vital to the care of more than 14 million asthmatics in the United States. The NAEPP urges that evaluation of the guidelines be given "high priority," and that evaluation should consider not only evidence of efficacy but effectiveness, costs, and cost effectiveness of the therapeutic recommendations put forth.

该建议旨在为首席研究员（PI）提供机会，以在咨询委员会的监督下评估医学成果，经济学和成本效益评估，该咨询委员会由高素质的赞助商和共同投资者组成。 PI拥有出色的临床培训，并在Channing实验室完成了为期两年的呼吸流行病学研究金。 此外，她获得了硕士学位哈佛公共卫生学院的临床流行病学。 该奖项与PI的背景相结合，为开发成功的独立研究职业提供了极大的潜力。 该提案的总体科学目标是确定具有与国家哮喘教育和预防计划（NAEPP）诊断和管理哮喘的指南中发表的建议相符的哮喘管理人员是否会导致临床结果的改善，并且具有与个人不符合管理不符的个人相对有效的成本。 我们建议使用有关在回顾性队列研究设计中在哈佛朝圣者卫生保健（HPHC）组装的成人和儿科哮喘患者队列的广泛信息。 我们假设患有哮喘药物疗法和非药理管理（门诊后续行动和专业转诊，哮喘教育，峰值流动利用，环境测量）的人将符合NAEPP指南的情况，将降低医疗保健的利用率，改善与个人相比的健康相关质量（HRQL）以及与其管理的人相比的成本有效。 该提议对于美国超过1400万次哮喘患者至关重要。 NAEPP敦促对准则进行评估“高优先级”，并且评估不仅应考虑有效性的证据，而且还应考虑提出的治疗建议的有效性，成本和成本效益。

项目成果

Concurrent use of metered dose inhalers without spacer and dry powder inhalers by asthmatic children adversely affect proper inhalation technique.

哮喘儿童同时使用不带储雾器的定量吸入器和干粉吸入器会对正确的吸入技术产生不利影响。

• DOI: 10.5580/2546
• 发表时间: 2011
• 期刊: The Internet journal of pediatrics and neonatology
• 作者: Alotaibi,Saad;Hassan,WalidM;Alhashimi,Hashim
• 通讯作者: Alhashimi,Hashim

The effect of treatment of allergic rhinitis on asthma morbidity, including emergency department visits.

过敏性鼻炎治疗对哮喘发病率的影响，包括急诊就诊。

• DOI: 10.1097/00130832-200302000-00005
• 发表时间: 2003
• 期刊: Current opinion in allergy and clinical immunology
• 影响因子: 2.8
• 作者: Fuhlbrigge,AnneL;Adams,RobertJ
• 通讯作者: Adams,RobertJ

Modeling the potential impact of a prescription drug copayment increase on the adult asthmatic medicaid population.

模拟处方药共付额增加对成人哮喘医疗补助人群的潜在影响。

• DOI: 10.1111/j.1524-4733.2007.00219.x
• 发表时间: 2008
• 期刊: Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research
• 作者: Bae,SeungJin;Paltiel,ADavid;Fuhlbrigge,AnneL;Weiss,ScottT;Kuntz,KarenM
• 通讯作者: Kuntz,KarenM