Maximizing Exercise for Persons with Fibromyalgia

为纤维肌痛患者提供最大程度的锻炼

• 批准号: 6660770
• 负责人: DANIEL S ROOKS
• 金额: $ 8.5万
• 依托单位: BETH ISRAEL DEACONESS MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-09-20 至 2005-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/6660770
• 关键词: aerobic exercise; behavioral /social science research tag; clinical research; clinical trials; exercise; female; fibromyalgia; functional ability; human subject; human therapy evaluation; longitudinal human study; muscle strength; outcomes research; physical fitness; psychological tests; quality of life; questionnaires; self care; sign /symptom; social support network; therapy compliance; women's health

DESCRIPTION (provided by applicant): Fibromyalgia (FMS) is a common, chronic musculoskeletal disorder and a growing cause of disability and medical care costs. With a poorly understood etiology and no known cure, current pharmacological treatment is mostly ineffective. Cardiovascular and flexibility forms of exercise have been reported to be beneficial and are often recommended However, there is a high rate of injury from exercise in the FMS population, and consequently, a very poor compliance rate with long-term exercise. Therefore, the long-term objective of this project is to optimize the exercise recommendations for persons with FMS and to identify factors to facilitate long-term compliance. The study aims to determine the efficacy of adding strength training to current exercise recommendations and to identify variables that potentially predict long-term exercise compliance in persons with FMS. This proposed project is a randomized controlled, intervention study comparing a program of strength training, cardiovascular and flexibility exercise (experimental) to a program of cardiovascular and flexibility exercise (current recommendation). Each program will include three group exercise sessions per week for 20 weeks. Upon completion of the group intervention, all subject will be given a copy of their exercise program, a diary/calendar for recording their exercise activities and will be followed for 6 months to examine exercise adherence and long-term effects. Subjects will be 150 women, 25 to 60 year old with a diagnosis of FMS, plus any men wishing to participate. Recruitment will be accomplished through direct referral from primary care physicians and rheumatologists, and through newspaper advertisements. Testing will occur a baseline, completion of the 20-week intervention and at 3 and 6 month follow up. Testing will assess health and functional status (FIQ SF36), symptom severity (FIQ SF36, Beck Depression Inventory), muscle strength (IRM) cardiovascular fitness (modified Bruce protocol), flexibility (Sit-and-Reach), and self-efficacy (Arthritis Self-Efficacy Scale). The expected outcomes of this study will advance the treatment paradigm for FMS by establishing an evidence based exercise prescription that can be integrated into a standard treatment plan and by identifying modifiable variable that may be used to facilitate long-term exercise maintenance in this population.

描述（由申请人提供）：纤维肌痛（FMS）是一种常见的慢性肌肉骨骼疾病，是残疾和医疗费用的日益增长的原因。目前的药理治疗尚无知识的病因，尚无已知的治愈方法，主要是无效的。据报道，心血管和柔韧性运动形式是有益的，通常建议使用FMS人群的运动率很高，因此长期运动的合规率很差。因此，该项目的长期目标是优化FMS患者的锻炼建议，并确定促进长期合规性的因素。该研究旨在确定将力量训练添加到当前的运动建议中的功效，并确定可能预测FMS患者长期运动依从性的变量。该提出的项目是一项随机对照的干预研究，将力量训练，心血管和灵活性运动（实验）与心血管和灵活性运动程序进行比较（当前建议）。每个程序将包括每周三个小组练习20周。小组干预完成后，所有受试者都将获得其锻炼计划的副本，记录其运动活动的日记/日历，并将在6个月内遵循练习遵守和长期影响。受试者将是150名女性，25至60岁，并诊断为FMS，以及任何希望参加的男性。招聘将通过初级保健医师和风湿病学家的直接转诊以及报纸广告来完成。测试将进行基线，完成20周的干预以及3个月的随访。测试将评估健康和功能状况（FIQ SF36），症状严重程度（FIQ SF36，BECK抑郁量清单），肌肉力量（IRM）心血管健身（修饰的Bruce方案），灵活性（坐姿）和自我效能感（关节炎自我效能低下）。这项研究的预期结果将通过建立基于证据的锻炼处方来推动FMS的治疗范式，该处方可以整合到标准治疗计划中，并通过识别可修改的变量，该变量可用于促进该人群的长期锻炼。